Publikationen im NUM
Hier finden Sie eine Liste der Publikationen, die im Zusammenhang mit dem Netzwerk Universitätsmedizin in der ersten und zweiten Förderphase entstanden sind.
N. Kreuzberger and
et al,
"Persistence of immunoglobulin G after natural infection with SARS-CoV-2",
Cochrane Database of Systematic Reviews,
2021.
| DOI: | 10.1002/14651858.CD014946 |
L. Michalick,
S. Weidenfeld,
B. Grimmer,
D. Fatykhova,
P. D. Solymosi,
F. Behrens,
M. Dohmen,
M. Brack,
S. Schulz,
E. Thomasch,
S. Simmons,
H. Müller-Redetzky,
N. Suttorp,
F. Kurth,
J. Neudecker,
M. Toennies,
T. T. Bauer,
S. Eggeling,
V. Corman,
A. Hocke,
M. Witzenrath,
S. Hippenstiel and
W. M. Kuebler,
"Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure",
Eur Respir J,
vol. 57,
no. 3,
pp. 2002384,
2021.
| DOI: | 10.1183/13993003.02384-2020 |
L. Michalick,
S. Weidenfeld,
B. Grimmer,
D. Fatykhova,
P. Solymosi,
F. Behrens,
M. Dohmen,
M. Brack,
S. Schulz,
E. Thomasch and
D. Stahl,
"Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure",
Eur Respir J,
vol. 57,
no. 3,
2021.
| DOI: | 10.1183/13993003.02384-2020 |
A. Joachim,
F. Dewald,
I. Suárez and
et al,
"Pooled RT-qPCR testing for SARS-CoV-2 surveillance in schools: A cluster randomised trial",
EClinicalMedicine,
vol. 39,
2021.
| DOI: | 10.1016/j.eclinm.2021.101082 |
M. Roessler,
F. Tesch,
M. Batram,
J. Jacob,
F. Loser,
O. Weidinger,
D. Wende,
A. Vivirito,
N. Toepfner,
M. Seifert,
O. Nagel,
C. König,
R. Jucknewitz,
J. P. Armann,
R. Berner,
M. Treskova-Schwarzbach,
D. Hertle,
S. Scholz,
S. Stern,
J. Schmitt and
D. Stahl,
"Post COVID-19 in children, adolescents, and adults: Results of a matched cohort study including more than 150,000 individuals with COVID-19",
2021.
| DOI: | 10.1101/2021.10.21.21265133 |
M. Augustin and
et al,
"Post-COVID syndrome in non-hospitalised patients with COVID-19: a longitudinal prospective cohort study",
The Lancet Regional Health. Europe,
vol. 6,
pp. 100122,
2021.
| DOI: | 10.1016/j.lanepe.2021.100122 |
D. Niemeyer,
S. Schroeder and
K. Friedmann,
"Post-entry, spike-dependent replication advantage of B.1.1.7 and B.1.617.2 over B.1 SARS-CoV-2 in an ACE2-deficient human lung cell line",
BioRxiv,
2021.
| DOI: | 10.1101/2021.10.20.465121 |
D. Niemeyer,
S. Schroeder,
K. Friedmann,
F. Weege,
J. Trimpert,
A. Richter,
S. Stenzel,
J. Jansen,
J. Emanuel,
J. Kazmierski,
F. Pott,
L. Jeworowski,
R. Olmer,
M. Jaboreck,
B. Tenner,
J. Papies,
J. Heinze,
F. Walper,
M. Schmidt,
N. Heinemann,
E. Möncke-Buchner,
T. Veith,
M. Baumgardt,
K. Hoffmann,
M. Widera,
T. Thao,
A. Balázs,
J. Schulze,
C. Mache,
M. Morkel,
S. Ciesek,
L. Hanitsch,
M. Mall,
A. Hocke,
V. Thiel,
K. Osterrieder,
T. Wolff,
U. Martin,
V. Corman,
M. Müller,
C. Goffinet and
C. Drosten,
"Post-entry, spike-dependent replication advantage of B.1.1.7 and B.1.617.2 over B.1 SARS-CoV-2 in an ACE2-deficient human lung cell line",
bioRxiv,
2021.
| DOI: | 10.1101/2021.10.20.465121 |
D. Niemeyer,
S. Schroeder,
K. Friedmann,
F. Weege,
J. Trimpert,
A. Richter,
S. Stenzel,
J. Jansen,
J. Emanuel,
J. Kazmierski,
F. Pott,
L. Jeworowski,
R. Olmer,
M. Jaboreck,
B. Tenner,
J. Papies,
J. Heinze,
F. Walper,
M. L. Schmidt,
N. Heinemann,
E. Möncke-Buchner,
T. Veith,
M. Baumgardt,
K. Hoffmann,
M. Widera,
T. Thao,
A. Balázs,
J. Schulze,
C. Mache,
M. Morkel,
S. Ciesek,
L. Hanitsch,
M. Mall,
A. Hocke,
V. Thiel,
K. Osterrieder,
T. Wolff,
U. Martin,
V. Corman,
M. Müller,
C. Goffinet and
C. Drosten,
"Post-entry, spike-dependent replication advantage of B.1.1.7 and B.1.617.2 over B.1 SARS-CoV-2 in an ACE2-deficient human lung cell line",
2021.
| DOI: | 10.1101/2021.10.20.465121 |
D. Niemeyer,
S. Schroeder,
K. Friedmann,
F. Weege,
J. Trimpert,
A. Richter,
S. Stenzel,
J. Jansen,
J. Emanuel,
J. Kazmierski,
F. Pott,
L. Jeworowski,
R. Olmer,
M. Jaboreck,
B. Tenner,
J. Papies,
J. Heinze,
F. Walper,
M. Schmidt,
N. Heinemann,
E. Möncke-Buchner,
T. Veith,
M. Baumgardt,
K. Hoffmann,
M. Widera,
T. Thao,
A. Balázs,
J. Schulze,
C. Mache,
M. Morkel,
S. Ciesek,
L. Hanitsch,
M. Mall,
A. Hocke,
V. Thiel,
K. Osterrieder,
T. Wolff,
U. Martin,
V. Corman,
M. Müller,
C. Goffinet and
C. Drosten,
"Post-entry, spike-dependent replication advantage of B.1.1.7 and B.1.617.2 over B.1 SARS-CoV-2 in an ACE2-deficient human lung cell line",
bioRxiv,
2021.
| DOI: | 10.1101/2021.10.20.465121 |
D. Niemeyer,
S. Schroeder,
K. Friedmann,
F. Weege,
J. Trimpert,
A. Richter,
S. Stenzel,
J. Jansen,
J. Emanuel,
J. Kazmierski,
F. Pott,
L. M. Jeworowski,
R. Olmer,
M. Jaboreck,
B. Tenner,
J. Papies,
J. Heinze,
F. Walper,
M. L. Schmidt,
N. Heinemann,
E. Möncke-Buchner,
T. Veith,
M. Baumgardt,
K. Hoffmann,
M. Widera,
T. T. N. Thao,
A. Balázs,
J. Schulze,
C. Mache,
M. Morkel,
S. Ciesek,
L. G. Hanitsch,
M. A. Mall,
A. C. Hocke,
V. Thiel,
K. Osterrieder,
T. Wolff,
U. Martin,
V. M. Corman,
M. A. Mueller,
C. Goffinet and
C. Drosten,
"Post-entry, spike-dependent replication advantage of B.1.1.7 and B.1.617.2 over B.1 SARS-CoV-2 in an ACE2-deficient human lung cell line",
BioRxiv,
2021.
| DOI: | 10.1101/2021.10.20.465121 |
| Datei: | https://doi.org/10.1101/2021.10.20.465121 |
[en]
M. Fuest,
P. Boor,
R. Knuechel,
For The DeRegCOVID,
P. Walter and
S. Salla,
"Postmortem conjunctival and nasopharyngeal swabs in SARS-CoV-2 infected and uninfected patients",
Acta Ophthalmologica,
vol. 99,
no. 4,
pp. e615—e617,
Jun.
2021.
| DOI: | 10.1111/aos.14559 |
| Datei: | https://onlinelibrary.wiley.com/doi/abs/10.1111/aos.14559 |
F. Heinrich,
K. Meißner,
F. Langenwalder,
K. Püschel,
D. Nörz,
A. Hoffmann,
M. Lütgehetmann,
E. Bibiza-Freiwald,
S. Pfefferle and
A. Heinemann,
"Postmortem stability of SARS-CoV-2 in nasopharyngeal mucosa",
Emerg Infect Dis,
vol. 27,
no. 1,
pp. 329-331,
2021.
| DOI: | 10.3201/eid2701.203112 |
[en-us]
F. Heinrich,
K. Meißner,
F. Langenwalder,
K. Püschel,
D. Nörz,
A. Hoffmann,
M. Lütgehetmann,
M. Aepfelbacher,
E. Bibiza-Freiwald,
S. Pfefferle and
A. Heinemann,
"Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa - Volume 27, Number 1—January 2021 - Emerging Infectious Diseases journal - CDC",
Emerging Infectious Diseases,
vol. 27,
no. 1,
pp. 329–31,
Jan.
2021.
| DOI: | 10.3201/eid2701.203112 |
| Datei: | https://wwwnc.cdc.gov/eid/article/27/1/20-3112_article |
[de]
P. Boor,
P. Eichhorn,
A. Hartmann,
S. F. Lax,
B. Märkl,
T. Menter,
K. Skok,
J. Slotta-Huspenina,
S. Stillfried,
A. Tzankov and
G. Weirich,
"Praktische Aspekte von COVID-19-Obduktionen",
Der Pathologe,
vol. 42,
no. 2,
pp. 197—207,
Mä.
2021.
| DOI: | 10.1007/s00292-021-00925-w |
| Datei: | https://doi.org/10.1007/s00292-021-00925-w |
P. Boor,
P. Eichhorn,
A. Hartmann,
S. F. Lax,
B. Märkl,
T. Menter,
K. Skok,
J. Slotta-Huspenina,
S. Stillfried,
A. Tzankov and
G. Weirich,
"Praktische Aspekte von COVID-19-Obduktionen [Practical aspects of COVID-19 autopsies]",
Pathologe,
vol. 42,
no. 2,
pp. 197-207,
2021.
M. Casagrande,
A. Fitzek,
M. S. Spitzer,
K. Püschel,
M. Glatzel,
S. Krasemann,
D. Nörz,
M. Lütgehetmann,
S. Pfefferle and
M. Schultheiss,
"Presence of SARS-CoV-2 RNA in the cornea of viremic patients with COVID-19",
JAMA Ophthalmol,
2021.
| DOI: | 10.1001/jamaophthalmol.2020.6339 |
M. Casagrande,
A. Fitzek,
M. S. Spitzer,
K. Püschel,
M. Glatzel,
S. Krasemann,
D. Nörz,
M. Lütgehetmann,
S. Pfefferle and
M. Schultheiss,
"Presence of SARS-CoV-2 RNA in the Cornea of Viremic Patients With COVID-19",
JAMA Ophthalmology,
vol. 139,
no. 4,
pp. 383—388,
Apr.
2021.
| DOI: | 10.1001/jamaophthalmol.2020.6339 |
| Datei: | https://doi.org/10.1001/jamaophthalmol.2020.6339 |
M. Oestreich,
D. Chen,
J. L. Schultze,
M. Fritz and
M. Becker,
"Privacy considerations for sharing genomics data",
EXCLI journal,
vol. 20,
pp. 1243–1260,
2021.
| DOI: | 10.17179/excli2021-4002 |
T. Weinberger,
J. Steffen,
A. Osterman and
et al,
"Prospective longitudinal serosurvey of healthcare workers in the first wave of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic in a quaternary care hospital in Munich, Germany",
Clin Infect Dis,
vol. 73,
no. 9,
2021.
| DOI: | 10.1093/cid/ciaa1935 |
[en]
A. Fitzek,
J. Schädler,
E. Dietz,
A. Ron,
M. Gerling,
A. L. Kammal,
L. Lohner,
C. Falck,
D. Möbius,
H. Goebels,
A. Gerberding,
A. S. Schröder,
J. Sperhake,
A. Klein,
D. Fröb,
H. Mushumba,
S. Wilmes,
S. Anders,
I. Kniep,
F. Heinrich,
F. Langenwalder,
K. Meißner,
P. Lange,
A. Zapf,
K. Püschel,
A. Heinemann,
M. Glatzel,
J. Matschke,
M. Aepfelbacher,
M. Lütgehetmann,
S. Steurer,
C. Thorns,
C. Edler and
B. Ondruschka,
"Prospective postmortem evaluation of 735 consecutive SARS-CoV-2-associated death cases",
Scientific Reports,
vol. 11,
no. 1,
pp. 19342,
Sep.
2021.
Nature Publishing Group.
Abstract:
Coronavirus disease 19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic with significant mortality. Accurate information on the specific circumstances of death and whether patients died from or with SARS-CoV-2 is scarce. To distinguish COVID-19 from non-COVID-19 deaths, we performed a systematic review of 735 SARS-CoV-2-associated deaths in Hamburg, Germany, from March to December 2020, using conventional autopsy, ultrasound-guided minimally invasive autopsy, postmortem computed tomography and medical records. Statistical analyses including multiple logistic regression were used to compare both cohorts. 84.1% (n = 618) were classified as COVID-19 deaths, 6.4% (n = 47) as non-COVID-19 deaths, 9.5% (n = 70) remained unclear. Median age of COVID-19 deaths was 83.0 years, 54.4% were male. In the autopsy group (n = 283), the majority died of pneumonia and/or diffuse alveolar damage (73.6%; n = 187). Thromboses were found in 39.2% (n = 62/158 cases), pulmonary embolism in 22.1% (n = 56/253 cases). In 2020, annual mortality in Hamburg was about 5.5% higher than in the previous 20 years, of which 3.4% (n = 618) represented COVID-19 deaths. Our study highlights the need for mortality surveillance and postmortem examinations. The vast majority of individuals who died directly from SARS-CoV-2 infection were of advanced age and had multiple comorbidities.
| DOI: | 10.1038/s41598-021-98499-3 |
| Datei: | https://www.nature.com/articles/s41598-021-98499-3 |
Abstract:
Coronavirus disease 19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic with significant mortality. Accurate information on the specific circumstances of death and whether patients died from or with SARS-CoV-2 is scarce. To distinguish COVID-19 from non-COVID-19 deaths, we performed a systematic review of 735 SARS-CoV-2-associated deaths in Hamburg, Germany, from March to December 2020, using conventional autopsy, ultrasound-guided minimally invasive autopsy, postmortem computed tomography and medical records. Statistical analyses including multiple logistic regression were used to compare both cohorts. 84.1% (n = 618) were classified as COVID-19 deaths, 6.4% (n = 47) as non-COVID-19 deaths, 9.5% (n = 70) remained unclear. Median age of COVID-19 deaths was 83.0 years, 54.4% were male. In the autopsy group (n = 283), the majority died of pneumonia and/or diffuse alveolar damage (73.6%; n = 187). Thromboses were found in 39.2% (n = 62/158 cases), pulmonary embolism in 22.1% (n = 56/253 cases). In 2020, annual mortality in Hamburg was about 5.5% higher than in the previous 20 years, of which 3.4% (n = 618) represented COVID-19 deaths. Our study highlights the need for mortality surveillance and postmortem examinations. The vast majority of individuals who died directly from SARS-CoV-2 infection were of advanced age and had multiple comorbidities.
A. Fitzek,
J. Schädler,
E. Dietz,
A. Ron,
M. Gerling,
A. Kammal,
L. Lohner,
C. Falck,
D. Möbius,
H. Goebels,
A. Gerberding,
A. Schröder,
J. Sperhake,
A. Klein,
D. Fröb,
H. Mushumba,
S. Wilmes,
I. Kniep,
F. Heinrich,
F. Langenwalder,
K. Meißner,
P. Lange,
A. Zapf,
K. Püschel,
A. Heinemann,
M. Glatzel,
J. Matschke,
M. Lütgehetmann,
S. Steurer,
C. Thorns,
C. Edler and
B. Ondruschka,
"Prospective postmortem evaluation of 735 consecutive SARS-CoV-2-associated death cases",
Sci Rep,
vol. 11,
no. 1,
pp. 19342,
Sep.
2021.
| DOI: | 10.1038/s41598-021-98499-3 |
D. Lapuente,
J. Fuchs,
J. Willar and
et al,
"Protective mucosal immunity against SARS-CoV-2 after heterologous systemic prime-mucosal boost immunization",
Nat Commun,
vol. 12,
no. 1,
2021.
| DOI: | 10.1038/s41467-021-27063-4 |
| Datei: | https://doi.org/10.1038/s41467-021-27063-4 |
M. Oberste,
L. M. Pusch,
R. Roth and
et al,
"Protocol of the Cologne Corona Surveillance (CoCoS) study: A prospective population-based cohort study",
BMC Public Health,
vol. 21,
no. 1,
2021.
| DOI: | 10.1186/s12889-021-11206-9 |
J. Schwartz and
D. Stahl,
"Psychische Belastung des Intensivpersonals: Kommunikationsseminare helfen",
Deutsches Ärzteblatt,
vol. 118,
no. 50,
2021.
N. Röthke,
D. Wollschläger,
A. Kunzler,
A. Rohde,
S. Molter,
M. Bodenstein,
A. Reif,
H. Walter,
K. Lieb and
O. Tüscher,
"Psychische Belastung, Resilienz und Absentismusneigung bei Gesundheitspersonal in Deutschland während der ersten COVID-19-Pandemiewelle im Frühjahr 2020",
Der Nervenarzt,
vol. 92,
no. 6,
pp. 579—590,
2021.
| DOI: | 10.1007/s00115-021-01132-x |
I. M. Veer,
A. Riepenhausen,
M. Zerban,
C. Wackerhagen,
L. Puhlmann,
H. Engen,
G. Köber,
S. A. Bögemann,
J. Weermeijer,
A. Uściłko,
N. Mor,
M. A. Marciniak,
A. D. Askelund,
S. Ayash,
G. Barsuola,
V. Bartkute-Norkuniene,
S. Battaglia,
Y. Bobko and
D. Stahl,
"Psycho-social factors associated with mental resilience in the Corona lockdown",
Translational Psychiatry,
vol. 11,
no. 1,
pp. 1—11,
2021.
| DOI: | 10.1038/s41398-020-01150-4 |
| Datei: | https://doi.org/10.1038/s41398-020-01150-4 |
E. Morawa,
C. Schug,
F. Geiser,
P. Beschoner,
L. Jerg-Bretzke,
K. Weidner,
N. Hiebel,
A. Borho and
Y. Erim,
"Psychosocial burden and working conditions during the COVID-19 pandemic in Germany: The VOICE survey among 3678 health care workers in hospitals",
Journal of Psychosomatic Research,
vol. 144,
pp. 110415,
2021.
| DOI: | 10.1016/j.jpsychores.2021.110415 |
L. Jerg-Bretzke,
M. Kempf,
M. N. Jarczok,
K. Weimer,
C. Hirning,
H. Gündel,
Y. Erim,
E. Morawa,
F. Geiser,
N. Hiebel,
K. Weidner and
P. Beschoner,
"Psychosocial Impact of the COVID-19 Pandemic on Healthcare Workers and Initial Areas of Action for Intervention and Prevention—The egePan/VOICE Study",
International Journal of Environmental Research and Public Health,
vol. 18,
no. 19,
pp. 10531,
2021.
| DOI: | 10.3390/ijerph181910531 |
G. Anton,
A. Kuehn-Steven,
M. K. Taucher,
I. Bernemann and
T. Illig,
"Quality management in times of COVID-19: Remote audits as tool to assess sample quality for NAPKON.",
European Biobank Week 2021,
2021.
A. Denzler,
M. L. Jacobs,
V. Witte and
et al,
"Rapid comparative evaluation of SARS-CoV-2 rapid point-of-care antigen tests",
MedRxiv,
2021.
| DOI: | 10.1101/2021.07.29.21261314 |
| Datei: | https://doi.org/10.1101/2021.07.29.21261314 |
S. Kluge,
J. J. Malin,
F. Fichtner,
O. J. Müller,
N. Skoetz and
C. Karagiannidis,
"Recommendations on the In-Hospital Treatment of Patients With COVID-19",
Dtsch Arztebl Int,
2021.
| DOI: | 10.3238/arztebl.m2021.0374 |
K. I. Wagner and
et al,
"Recruitment of highly cytotoxic CD8+ T cell receptors in mild SARS-CoV-2 infection",
Cell reports,
vol. 35,
pp. 110214,
2021.
| DOI: | 10.1016/j.celrep.2021.110214 |
S. Bauer,
S. Contreras,
J. Dehning,
M. Linden,
E. Iftekhar,
S. B. Mohr,
A. Olivera-Nappa and
V. Priesemann,
"Relaxing restrictions at the pace of vaccination increases freedom and guards against further COVID-19 waves",
PLOS Computational Biology,
vol. 17,
no. 9,
pp. e1009288,
2021.
| DOI: | 10.1371/journal.pcbi.1009288 |
D. Thole,
T. Ole Diesterhöft,
S. Vogel,
M. Greve,
E. Bauer,
S. Strathmann,
C. Elsner,
N. Kolbe and
D. Krefting,
"Relevant Aspects for Sustainable Open Source Pandemic Apps and Platform Deployment with Focus on Community Building",
Stud Health Technol Inform,
vol. 283,
pp. 186—193,
2021.
| DOI: | 10.3233/SHTI210580 |
K. Ansems,
F. Grundeis,
K. Dahms,
A. Mikolajewska,
V. Thieme,
V. Piechotta,
M. Metzendorf,
M. Stegemann,
C. Benstoem and
F. Fichtner,
"Remdesivir for the treatment of COVID‐19",
Cochrane Database of Systematic Reviews,
vol. 2021,
no. 8,
pp. CD014962,
2021.
| DOI: | 10.1002/14651858.CD014962 |
D. Wurzer,
P. Spielhagen,
A. Siegmann,
A. Gercekcioglu,
J. Gorgass,
S. Henze,
Y. Kolar,
F. Koneberg,
S. Kukkonen,
H. McGowan,
S. Schmid-Eisinger,
A. Steger,
M. Dommasch,
H. U. Haase,
A. Müller,
E. Martens,
B. Haller,
K. M. Huster and
G. Schmidt,
"Remote monitoring of COVID-19 positive high-risk patients in domestic isolation: A feasibility study",
PLOS ONE,
vol. 16,
no. 9,
pp. e0257095,
2021.
| DOI: | 10.1371/journal.pone.0257095 |
| Datei: | https://doi.org/10.1371/journal.pone.0257095 |
S. Graf,
L. Engelmann,
O. Wölfler and
D. Stahl,
"Reopening the Bavarian State Opera Safely: Hygiene Strategies and Incidence of COVID-19 in Artistic Staff During Theater Season 2020/2021",
Journal of Voice,
2021.
| DOI: | 10.1016/j.jvoice.2021.11.012 |
| Datei: | https://doi.org/10.1016/j.jvoice.2021.11.012 |
M. Salholz-Hillel,
P. Grabitz,
M. Pugh-Jones,
D. Strech and
N. J. DeVito,
"Results availability and timeliness of registered COVID-19 clinical trials: interim cross-sectional results from the DIRECCT study",
BMJ Open,
vol. 11,
no. 11,
pp. e053096,
2021.
| DOI: | 10.1136/bmjopen-2021-053096 |
F. Nordsiek,
E. Bodenschatz,
G. Bagheri and
et al,
"Risk assessment for airborne disease transmission by poly-pathogen aerosols",
PLOS ONE,
2021.
| DOI: | 10.1371/journal.pone.0248004 |
M. Wunsch,
D. Aschemeier,
E. Hegera and
et al,
"Safe and effective pool testing for SARS-CoV-2 detection",
J Clin Virol,
vol. 145,
2021.
| DOI: | 10.1016/j.jcv.2021.105018 |
S. Reis,
M. Popp,
B. Schmid,
M. Stegemann,
M. Metzendorf,
P. Kranke,
P. Meybohm and
S. Weibel,
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