Publikationen im NUM

Hier finden Sie eine Liste der Publikationen, die im Zusammenhang mit dem Netzwerk Universitätsmedizin in der ersten und zweiten Förderphase entstanden sind.

T. Hempel and et al, "Synergistic inhibition of SARS-CoV-2 cell entry by otamixaban and covalent protease inhibitors: pre-clinical assessment of pharmacological and molecular properties", Chemical Science, vol. 12, pp. 12600–12609, 2021.
DOI:10.1039/D1SC01494C
C. Wagner, M. Griesel, A. Mikolajewska, A. Mueller, M. Nothacker, K. Kley, M. Metzendorf, A. Fischer, M. Kopp, M. Stegemann, N. Skoetz and F. Fichtner, "Systemic corticosteroids for the treatment of COVID-19", Cochrane Database of Systematic Reviews, vol. 2021, pp. CD014963, 2021.
DOI:10.1002/14651858.CD014963
[en] M. O'Hare, D. Amarnani, H. A. B. Whitmore, M. An, C. Marino, L. Ramos, S. Delgado-Tirado, X. Hu, N. Chmielewska, A. Chandrahas, A. Fitzek, F. Heinrich, S. Steurer, B. Ondruschka, M. Glatzel, S. Krasemann, D. Sepulveda-Falla, D. Lagares, J. Pedron, J. H. Bushweller, P. Liu, J. F. Arboleda-Velasquez and L. A. Kim, "Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators", The American Journal of Pathology, vol. 191, no. 7, pp. 1193—1208, Jul. 2021.
DOI:10.1016/j.ajpath.2021.04.006
Datei:https://www.sciencedirect.com/science/article/pii/S0002944021001619
M. O'Hare, H. A. B. Whitmore, C. Marino, L. Ramos, S. Delgado-Tirado, X. Hu, N. Chmielewska, A. Chandrahas and D. Stahl, "Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators", Am J Pathol, vol. 191, no. 7, pp. 1193-1208, 2021.
DOI:10.1016/j.ajpath.2021.04.006
M. Baldinger, A. Heinrich, E. Martens, M. Dommasch, A. Muller, A. Siegmann, G. Schmidt and K. V. Laerhoven, "TELECOVID: Remote Vital Signs Monitoring of COVID-19 Risk Patients in Home Isolation With an In-Ear Wearable", IEEE Pervasive Computing, vol. 20, no. 2, pp. 58—62, 2021.
DOI:10.1109/MPRV.2021.3066825
G. Nouailles, E. Wyler, P. Pennitz, D. Postmus, D. Vladimirova and e. a. Kazmierski, "Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19", Nat Commun, vol. 12, pp. 4869, 2021.
DOI:10.1038/s41467-021-25030-7
G. Nouailles, E. Wyler, P. Pennitz, D. Postmus, D. Vladimirova, J. Kazmierski, F. Pott, K. Dietert, M. Muelleder, V. Farztdinov and D. Stahl, "Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19", Nat Commun, vol. 12, no. 1, pp. 4869, 2021.
DOI:10.1038/s41467-021-25030-7
G. Nouailles, E. Wyler, P. Pennitz, D. Postmus, D. Vladimirova, J. Kazmierski, F. Pott, K. Dietert, M. Muelleder, V. Farztdinov, B. Obermayer, B. Sawitzki, C. Drosten, L. E. Sander, N. Suttorp, M. Ralser, D. Beule, A. Gruber, C. Goffinet, M. Landthaler, J. Trimpert, M. Witzenrath, S. Wienhold and T. Hoefler, "Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19", Nat Commun.2021;12(1):4869, 2021.
L. Krüger, M. Gaeddert, F. Tobian and D. Stahl, "The Abbott PanBio WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test for SARS-CoV-2—Evaluation of the accuracy and ease-of-use", PLOS ONE, vol. 16, no. 5, 2021.
DOI:10.1371/journal.pone.0247918
Datei:https://doi.org/10.1371/journal.pone.0247918
M. Witzenrath and W. Kuebler, "The CypA-netics of Ventilator-induced Lung Injury", Am J Respir Crit Care Med, vol. 204, no. 4, pp. 385—387, 2021.
DOI:10.1164/rccm.202104-0919ED
M. Witzenrath and W. Kuebler, "The CypA-netics of Ventilator-induced Lung Injury. Am J Respir Crit Care Med", 204(4):385-387, 2021.
C. Ramirez Alvarez, C. Kee, A. K. Sharma, L. Thomas, F. I. Schmidt and e. a. Stanifer, "The endogenous cellular protease inhibitor SPINT2 controls SARS-CoV-2 viral infection and is associated with disease severity", PLOS Pathogens, vol. 17, no. 5, pp. e1009687, 2021.
DOI:10.1371/journal.ppat.1009687
[en] A. S. Schröder, C. Edler, B. Ondruschka, K. Püschel, J. Schädler, A. Heinemann, F. Heinrich, M. Lütgehetmann, S. Pfefferle, M. Aepfelbacher, A. Fitzek and J. Sperhake, "The handling of SARS-CoV-2 associated deaths - infectivity of the body", Forensic Science, Medicine and Pathology, vol. 17, no. 3, pp. 411—418, Sep. 2021.
DOI:10.1007/s12024-021-00379-9
Datei:https://doi.org/10.1007/s12024-021-00379-9
F. Hornung, J. Rogal, P. Loskill, B. Löffler and S. Deinhardt-Emmer, "The Inflammatory Profile of Obesity and the Role on Pulmonary Bacterial and Viral Infections", Int J Mol Sci, vol. 22, 2021.
V. Clemens, P. Beschoner, M. Jarczok, K. Weimer, M. Kempf, E. Morawa, F. Geiser, S. Steudte-Schmiedgen, H. Gündel, J. Fegert and L. Jerg-Bretzke, "The mediating role of COVID-19-related burden in the association between adverse childhood experiences and emotional exhaustion: Results of the egePan–VOICE study", European Journal of Psychotraumatology, vol. 12, no. 1, pp. 1976441, 2021.
DOI:10.1080/20008198.2021.1976441
M. Hoffmann and et al, "The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic", Cell, 2021.
DOI:10.1016/j.cell.2021.12.032
J. Wachinger, I. D. Olaru, S. Horner and et al, "The potential of SARS-CoV-2 antigen-detection tests in the screening of asymptomatic persons", Clin Microbiol Infect, vol. 27, no. 11, 2021.
DOI:10.1016/j.cmi.2021.07.020
Datei:https://doi.org/10.1016/j.cmi.2021.07.020
[en] H. Bösmüller, M. Matter, F. Fend and A. Tzankov, "The pulmonary pathology of COVID-19", Virchows Archiv, vol. 478, no. 1, pp. 137—150, Jan. 2021.
DOI:10.1007/s00428-021-03053-1
Datei:https://doi.org/10.1007/s00428-021-03053-1
I. Panchyrz, S. Pohl, J. Hoffmann, C. Gatermann, F. Walther, L. Harst, H. Held, C. Kleber and J. Schmitt, "The role of university hospitals in regional health care management for coping with the COVID-19 pandemic", Zeitschrift Für Evidenz, Fortbildung Und Qualität Im Gesundheitswesen, vol. 167, pp. 68—77, 2021.
DOI:10.1016/j.zefq.2021.09.004
[en] J. Wenzel, J. Lampe, H. Müller-Fielitz, R. Schuster, M. Zille, K. Müller, M. Krohn, J. Körbelin, L. Zhang, Ü. Özorhan, V. Neve, J. U. G. Wagner, D. Bojkova, M. Shumliakivska, Y. Jiang, A. Fähnrich, F. Ott, V. Sencio, C. Robil, S. Pfefferle, F. Sauve, C. F. F. Coêlho, J. Franz, F. Spiecker, B. Lembrich, S. Binder, N. Feller, P. König, H. Busch, L. Collin, R. Villaseñor, O. Jöhren, H. C. Altmeppen, M. Pasparakis, S. Dimmeler, J. Cinatl, K. Püschel, M. Zelic, D. Ofengeim, C. Stadelmann, F. Trottein, R. Nogueiras, R. Hilgenfeld, M. Glatzel, V. Prevot and M. Schwaninger, "The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells", Nature Neuroscience, vol. 24, no. 11, pp. 1522—1533, Nov. 2021.
DOI:10.1038/s41593-021-00926-1
Datei:https://www.nature.com/articles/s41593-021-00926-1
J. Wenzel, J. Lampe, H. Müller-Fielitz and et al, "The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells", Nat Neurosci, vol. 24, no. 11, pp. 1522-1533, 2021.
DOI:10.1038/s41593-021-00926-1
K. Kitazawa, S. Deinhardt-Emmer, T. Inomata, S. Deshpande and C. Sotozono, "The Transmission of SARS-CoV-2 Infection on the Ocular Surface and Prevention Strategies", Cells, vol. 10, 2021.
M. R. Muzoora and et al, "Towards FAIR Patient Reported Outcome: Application of the Interoperability Principle for Mobile Pandemic Apps", Stud Health Technol Inform, vol. 287, pp. 85—86, 2021.
DOI:10.3233/SHTI210315
A. Wulff, P. Biermann, T. Landesberger, T. Baumgartl, C. Schmidt, A. Y. Alhaji, K. Schick, P. Waldstein, Y. Zhu, H. I. C. S. Group, D. Krefting, S. Scheithauer and M. Marschollek, "Tracing COVID-19 Infection Chains Within Healthcare Institutions – Another Brick in the Wall Against SARS-CoV-2", Studies in Health Technology and Informatics, 2021.
DOI:10.3233/SHTI220168
Datei:https://doi.org/10.3233/SHTI220168
A. Wulff, P. Biermann, T. von Landesberger, T. Baumgartl, C. Schmidt, A. Alhaji, K. Schick, P. Waldstein, Y. Zhu, HiGHmed Infection Control Study Group, D. Krefting, S. Scheithauer and M. Marschollek, "Tracing COVID-19 infection chains within healthcare institutions: Another brick in the wall against SARS-CoV-2", Studies in Health Technology and Informatics, vol. 290: MEDINFO 2021: One World, One Health – Global, pp. 699 - 703, 2021.
DOI:10.3233/SHTI220168
A. Wulff, P. Biermann, T. von Landesberger, T. Baumgartl, C. Schmidt, A. Alhaji, K. Schick, P. Waldstein, Y. Zhu, HiGHmed Infection Control Study Group, D. Krefting, S. Scheithauer and M. Marschollek, "Tracing COVID-19 infection chains within healthcare institutions: Another brick in the wall against SARS-CoV-2", Studies in Health Technology and Informatics, vol. 290: MEDINFO 2021: One World, One Health – Global, pp. 699 - 703, 2021.
DOI:10.3233/SHTI220168
Datei:https://imia-medinfo.org/medinfo21/
E. Wyler, K. Mosbauer, V. Franke, A. Diag, L. T. Gottula and e. a. Arsie, "Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy", iScience, vol. 24, pp. 102151, 2021.
DOI:10.1016/j.isci.2021.102151
[Deutsch] M. Verhoff, K. Püschel and B. Ondruschka, "Über die Ansteckungsgefahr beim Umgang mit SARS-CoV-2-positiven Leichen", Bestattungskultur, no. 5, pp. 24—28, 2021.
Datei:https://fis-uke.de/portal/de/publications/uber-die-ansteckungsgefahr-beim-umgang-mit-sarscov2positiven-leichen(a5affc27-e329-4aa4-8a39-566dbe2728c7).html
I. Backhaus, D. Hermsen, J. Timm, F. Boege, N. Lübke, K. Göbels, D. Lieth and N. Dragano, "Under-ascertainment of COVID-19 cases among first responders: a seroepidemiological study", Occupational Medicine, pp. kqab164, 2021.
DOI:10.1093/occmed/kqab164
S. Schuster, J. Lisack, I. Subota, H. Zimmermann, C. Reuter and e. a. Mueller, "Unexpected plasticity in the life cycle of Trypanosoma brucei", Elife, vol. 10, 2021.
DOI:10.7554/eLife.62090
C. Klinger, J. Burns, A. Movsisyan, R. Biallas, S. L. Norris, J. E. Rabe, J. M. Stratil, S. Voss, K. Wabnitz, E. Rehfuess and B. Verboom, "Unintended health and societal consequences of international travel measures during the COVID-19 pandemic: A scoping review", J Travel Med, 2021.
DOI:10.1093/jtm/taab123
M. Witkowski, C. Tizian, M. Ferreira-Gomes, D. Niemeyer, T. C. Jones and e. a. Heinrich, "Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells", Nature, 2021.
DOI:10.1038/s41586-021-03859-9
M. Witkowski, C. Tizian, M. Ferreira-Gomes and et al, "Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells", Nature, vol. 600, no. 7888, pp. 295-301, 2021.
DOI:10.1038/s41586-021-04142-6
M. Witkowski and et al, "Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells", Nature, 2021.
DOI:10.1038/s41586-021-04142-6
[en] M. Witkowski, C. Tizian, M. Ferreira-Gomes, D. Niemeyer, T. C. Jones, F. Heinrich, S. Frischbutter, S. Angermair, T. Hohnstein, I. Mattiola, P. Nawrath, S. McEwen, S. Zocche, E. Viviano, G. A. Heinz, M. Maurer, U. Kölsch, R. L. Chua, T. Aschman, C. Meisel, J. Radke, B. Sawitzki, J. Roehmel, K. Allers, V. Moos, T. Schneider, L. Hanitsch, M. A. Mall, C. Conrad, H. Radbruch, C. U. Duerr, J. A. Trapani, E. Marcenaro, T. Kallinich, V. M. Corman, F. Kurth, L. E. Sander, C. Drosten, S. Treskatsch, P. Durek, A. Kruglov, A. Radbruch, M. Mashreghi and A. Diefenbach, "Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells", Nature, vol. 600, no. 7888, pp. 295—301, Dez. 2021.
DOI:10.1038/s41586-021-04142-6
Datei:https://www.nature.com/articles/s41586-021-04142-6
[German] S. Berezowska, P. Boor, D. Jonigk and V. Tischler, "Update on thoracic pathology 2021-report of the working group thoracic pathology of the German Society of Pathology", Pathologe, pp. 1-4, 2021.
DOI:10.1007/s00292-021-00991-0
[de] S. Berezowska, P. Boor, D. Jonigk and V. Tischler, "Update Thoraxpathologie 2021 – Bericht der Arbeitsgemeinschaft", Der Pathologe, vol. 42, no. 2, pp. 199—202, Dez. 2021.
DOI:10.1007/s00292-021-00991-0
Datei:https://doi.org/10.1007/s00292-021-00991-0
D. Tampe, S. Hakroush, M. Bösherz, J. Franz, H. Hofmann-Winkler, S. Pöhlmann, S. Kluge, O. Moerer, C. Stadelmann, P. Ströbel, M. S. Winkler and B. Tampe, "Urinary Levels of SARS-CoV-2 Nucleocapsid Protein Associate With Risk of AKI and COVID-19 Severity: A Single-Center Observational Study", Frontiers in Medicine, vol. 8, pp. 644715, Mai 2021.
DOI:10.3389/fmed.2021.644715
Datei:https://www.frontiersin.org/articles/10.3389/fmed.2021.644715
[en] C. Dittmayer, J. Meinhardt, H. Radbruch, J. Radke, B. I. Heppner, F. L. Heppner, W. Stenzel, G. Holland and M. Laue, "Using EM data to understand COVID-19 pathophysiology – Authors' reply", The Lancet, vol. 397, no. 10270, pp. 197—198, Jan. 2021.
DOI:10.1016/S0140-6736(21)00032-5
Datei:https://www.sciencedirect.com/science/article/pii/S0140673621000325
T. S. Boender, W. Cai, M. Schranz and D. Stahl, "Using routine emergency department data for syndromic surveillance of acute respiratory illness before and during the COVID-19 pandemic in Germany, week 10-2017 and 10-2021", medRxiv, Aug. 2021.
DOI:10.1101/2021.08.19.21262303
O. Gross, O. Moerer, T. Rauen and et al, "Validation of a Prospective Urinalysis-Based Prediction Model for ICU Resources and Outcome of COVID-19 Disease: A Multicenter Cohort Study", J Clin Med, vol. 10, no. 14, 2021.
DOI:10.3390/jcm10143049
L. Nicolai, A. Leunig, S. Brambs, R. Kaiser, M. Joppich, M. Hoffknecht, C. Gold, A. Engel, V. Polewka, M. Muenchhoff and D. Stahl, "Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID-19 from influenza pneumonia", J Thromb Haemost, vol. 19, no. 2, pp. 574-581, 2021.
DOI:10.1111/jth.15179
[en] L. Nicolai, A. Leunig, S. Brambs, R. Kaiser, M. Joppich, M. Hoffknecht, C. Gold, A. Engel, V. Polewka, M. Muenchhoff, J. C. Hellmuth, A. Ruhle, S. Ledderose, T. Weinberger, H. Schulz, C. Scherer, M. Rudelius, M. Zoller, O. T. Keppler, B. Zwißler, M. Bergwelt‐Baildon, S. Kääb, R. Zimmer, R. D. Bülow, S. Stillfried, P. Boor, S. Massberg, K. Pekayvaz and K. Stark, "Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID‐19 from influenza pneumonia", Journal of Thrombosis and Haemostasis, vol. 19, no. 2, pp. 574—581, Feb. 2021.
DOI:10.1111/jth.15179
Datei:https://www.sciencedirect.com/science/article/pii/S1538783622006626
K. Roedl, S. Heidenreich, S. Pfefferle, D. Jarczak, T. T. Urbanowicz, D. Nörz, M. Aepfelbacher, N. Kröger, S. Kluge, M. Lütgehetmann, M. Christopeit and D. Wichmann, "Viral Dynamics of SARS-CoV-2 in Critically Ill Allogeneic Hematopoietic Stem Cell Transplant Recipients and Immunocompetent Patients with COVID-19", American Journal of Respiratory and Critical Care Medicine, vol. 203, no. 2, pp. 242—245, Jan. 2021.
DOI:10.1164/rccm.202009-3386LE
Datei:https://www.atsjournals.org/doi/10.1164/rccm.202009-3386LE
K. Roedl, S. Heidenreich, S. Pfefferle, D. Jarczak, T. T. Urbanowicz, D. Nörz, N. Kröger, S. Kluge, M. Lütgehetmann, M. Christopeit and D. Wichmann, "Viral Dynamics of SARS-CoV-2 in Critically Ill Allogeneic Hematopoietic Stem Cell Transplant Recipients and Immunocompetent Patients with COVID-19", Am J Respir Crit Care Med, vol. 203, no. 2, pp. 242-245, 2021.
J. K. Stroehlein, J. Wallqvist, C. Iannizzi, A. Mikolajewska, M. Metzendorf, C. Benstoem, P. Meybohm, M. Becker, N. Skoetz, M. Stegemann and V. Piechotta, "Vitamin D supplementation for the treatment of COVID-19: a living systematic review", Cochrane Database of Systematic Reviews, vol. 2021, pp. CD015043, 2021.
DOI:10.1002/14651858.CD015043
S. Weigang, J. Fuchs, G. Zimmer and et al, "Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants", Nat Commun, vol. 12, no. 1, 2021.
DOI:10.1038/s41467-021-26602-3
Datei:https://doi.org/10.1038/s41467-021-26602-3
D. Eggers, "Best practice models for nursing care in the COVID-19-pandemic: a web-based survey. Joint Scientific Summer Conference DGP/EANS. Lessons learned from the pandemic in different nursing settings. 02.07.2021. Vortrag.", 2021.
M. Metzendorf, J. Hildebrandt, T. Jakob and R. M. Featherstone, "Das Cochrane COVID-19 Studienregister – eine studienbasierte, strukturierte Datenbank zur effizienten Identifizierung wissenschaftlicher Evidenz" in Vortrag. 22. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin, 2021.
M. Winter and et al, "Exploring the Usability of the German COVID-19 Contact Tracing App in a Combined Eye Tracking and Retrospective Think Aloud Study" in 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society, 2021, pp. 2215—2221.
DOI:10.1109/EMBC48546.2021.9630667