Publikationen im NUM
Hier finden Sie eine Liste der Publikationen, die im Zusammenhang mit dem Netzwerk Universitätsmedizin in der ersten und zweiten Förderphase entstanden sind.
F. Heinrich,
C. Romich,
T. Zimmermann,
I. Kniep,
A. Fitzek,
S. Steurer,
M. Glatzel,
D. Nörz,
T. Günther,
M. Czech-Sioli,
N. Fischer,
A. Grundhoff,
M. Lütgehetmann and
B. Ondruschka,
"Dying of VOC-202012/01 - multimodal investigations in a death case of the SARS-CoV-2 variant",
Int J Legal Med,
pp. 1-10,
2021.
| DOI: | 10.1007/s00414-021-02618-8 |
S. Deinhardt-Emmer,
D. Wittschieber,
J. Sanft,
S. Kleemann,
S. Elschner and
e. a. Haupt,
"Early postmortem mapping of SARS-CoV-2 RNA in patients with COVID-19 and the correlation with tissue damage",
Elife,
vol. 10,
2021.
L. Gieselmann and
et al,
"Effective high-throughput isolation of fully human antibodies targeting infectious pathogens",
Nature Protocols,
2021.
| DOI: | 10.1038/s41596-021-00554-w |
A. Deckert and
D. Stahl,
"Effectiveness and cost-effectiveness of four different strategies for SARS-CoV-2 surveillance in the general population (CoV-Surv Study): a structured summary of a study protocol for a cluster-randomised, two-factorial controlled trial",
Trials,
vol. 22,
no. 1,
2021.
| DOI: | 10.1186/s13063-020-04982-z |
| Datei: | https://doi.org/10.1186/s13063-020-04982-z |
A. Deckert and
et al,
"Effectiveness and cost-effectiveness of four different strategies for SARS-CoV-2 surveillance in the general population (CoV-Surv Study): a structured summary of a study protocol for a cluster-randomised, two-factorial controlled trial",
Trials,
vol. 22,
no. 1,
2021.
| DOI: | 10.1186/s13063-020-04982-z |
A. Deckert and
D. Stahl,
"Effectiveness and cost-effectiveness of four different strategies for SARS-CoV-2 surveillance in the general population (CoV-Surv Study): study protocol for a two-factorial randomized controlled multi-arm trial with cluster sampling",
Trials,
vol. 22,
no. 1,
2021.
| DOI: | 10.1186/s13063-021-05619-5 |
| Datei: | https://doi.org/10.1186/s13063-021-05619-5 |
A. Deckert,
M. De Allegri and
et al,
"Effectiveness and cost-effectiveness of four different strategies for SARS-CoV-2 surveillance in the general population (CoV-Surv Study): study protocol for a two-factorial randomized controlled multi-arm trial with cluster sampling",
Trials,
vol. 22,
no. 1,
2021.
| DOI: | 10.1186/s13063-021-05619-5 |
P. Beschoner,
M. Jarczok,
M. Kempf,
K. Weimer,
F. Geiser,
N. Hiebel,
Y. Erim,
E. Morawa,
S. Steudte-Schmiedgen and
L. Jerg-Bretzke,
"egePan-VOICE study on the psychosocial burden of the Covid-19 pandemic among medical technical assistants",
Z Psychosom Med Psychother,
2021.
S. Zellmer,
M. Kahn,
A. Ebigbo and
et al,
"Ein Jahr Covid-19: Testung, Verwendung von Schutzausrüstung und Auswirkungen auf die Gastrointestinale Endoskopie in Deutschland",
Z Gastroenterol,
vol. 59,
no. 8,
2021.
| DOI: | 10.1055/s-0041-1734140 |
M. Kahn,
S. Zellmer,
A. Ebigbo and
et al,
"Ein Jahr Covid-19: Testung, Verwendung von Schutzausrüstung und Auswirkungen auf die Gastrointestinale Endoskopie in Deutschland",
Z Gastroenterol,
vol. 59,
no. 12,
2021.
| DOI: | 10.1055/a-1649-8184 |
B. Jensen,
N. Luebke,
T. Feldt,
V. Keitel,
T. Brandenburger,
D. Kindgen-Milles,
M. Lutterbeck,
N. F. Freise,
D. Schoeler,
R. Haas,
A. Dilthey,
O. Adams,
A. Walker,
J. Timm and
T. Luedde,
"Emergence of the E484K mutation in SARS-COV-2-infected immunocompromised patients treated with bamlanivimab in Germany",
The Lancet Regional Health- Europe,
2021.
| DOI: | 10.1016/j.lanepe.2021.100164 |
| Datei: | https://doi.org/10.1016/j.lanepe.2021.100164 |
B. Jensen,
N. Luebke,
T. Feldt,
V. Keitel,
T. Brandenburger,
D. Kindgen-Milles,
M. Lutterbeck,
N. Freise,
D. Schoeler,
R. Haas,
A. Dilthey,
A. Walker,
J. Timm and
T. Luedde,
"Emergence of the E484K mutation in SARS-COV-2-infected immunocompromised patients treated with bamlanivimab in Germany",
The Lancet regional health. Europe,
vol. 8,
pp. 100164,
2021.
| DOI: | 10.1016/j.lanepe.2021.100164 |
B. Jensen,
N. Luebke,
T. Feldt and
et al,
"Emergence of the E484K mutation in SARS-COV-2-infected immunocompromised patients treated with bamlanivimab in Germany",
Lancet Reg Health Eur,
vol. 8,
2021.
| DOI: | 10.1016/j.lanepe.2021.100164 |
L. Ruhl and
et al,
"Endothelial dysfunction contributes to severe COVID-19 in combination with dysregulated lymphocyte responses and cytokine networks",
Signal transduction and targeted therapy,
vol. 6,
pp. 418,
2021.
| DOI: | 10.1038/s41392-021-00819-6 |
[German]
S. Stillfried,
P. Boor and
D. PANDEMIcs,
"Entwicklung eines kooperativen Obduktionsnetzwerks aus Pathologie, Neuropathologie und Rechtsmedizin",
Pathologe,
pp. 1-5,
2021.
| DOI: | 10.1007/s00292-021-01004-w |
[de]
S. Stillfried,
P. Boor and
D. PANDEMIcs,
"Entwicklung eines kooperativen Obduktionsnetzwerks aus Pathologie, Neuropathologie und Rechtsmedizin",
Der Pathologe,
vol. 42,
no. 2,
pp. 129—134,
Dez.
2021.
| DOI: | 10.1007/s00292-021-01004-w |
| Datei: | https://doi.org/10.1007/s00292-021-01004-w |
[German]
F. Zack,
S. Nigbur,
H. Derani,
D. Boy,
A. Port and
A. Büttner,
"Erste Ergebnisse der Obduktionen der im Zusammenhang mit den SARS-CoV-2-Infektionen Verstorbenen aus der Unimedizin Rostock",
Ärzteblatt Mecklenburg-Vorpommern,
vol. 31,
pp. 125—128,
2021.
| Datei: |  https://aerzteblatt-mvp.de/pdf/mv2104_125.pdf |
F. Zack,
S. Nigbur,
J. Manhart,
H. Derani,
D. Boy,
V. Kolbe and
A. Büttner,
"Erste Ergebnisse der Obduktionen der im Zusammenhang mit den SARS-CoV-2-Infektionen Verstorbenen aus der Unimedizin Rostock",
Ärztebl Meckl-Vorpom,
vol. 31,
pp. 125-128,
2021.
A. Revet,
J. Hebebrand,
L. Kehoe,
C. Child,
S. Bender and
P. Klauser,
"ESCAP CovCAP survey of heads of academic departments to assess the perceived initial (April/May 2020) impact of the COVID-19 pandemic on child and adolescent psychiatry services",
European Child & Adolescent Psychiatry,
2021.
| DOI: | 10.1007/s00787-020-01699-x |
R. Wagner,
D. Peterhoff,
S. Beileke and
et al,
"Estimates and determinants of SARS-Cov-2 seroprevalence and infection fatality ratio using latent class analysis: The population-based Tirschenreuth study in the hardest-hit German county in spring 2020",
Viruses,
vol. 13,
no. 6,
2021.
| DOI: | 10.3390/v13061118 |
| Datei: | https://doi.org/10.3390/v13061118 |
T. C. Jones and
et al,
"Estimating infectiousness throughout SARS-CoV-2 infection course",
Science (New York, N.Y.),
2021.
| DOI: | 10.1126/science.abi5273 |
[en]
D. Nörz,
M. Grunwald,
F. Olearo,
N. Fischer,
M. Aepfelbacher,
S. Pfefferle and
M. Lütgehetmann,
"Evaluation of a fully automated high-throughput SARS-CoV-2 multiplex qPCR assay with built-in screening functionality for del-HV69/70- and N501Y variants such as B.1.1.7",
Journal of Clinical Virology,
vol. 141,
pp. 104894,
Aug.
2021.
Abstract:
.
| DOI: | 10.1016/j.jcv.2021.104894 |
| Datei: | https://www.sciencedirect.com/science/article/pii/S138665322100161X |
Abstract:
.
K. A. Eberhardt and
et al,
"Evaluation of a New Spike (S)-Protein-Based Commercial Immunoassay for the Detection of Anti-SARS-CoV-2 IgG",
Microorganisms,
vol. 9,
2021.
| DOI: | 10.3390/microorganisms9040733 |
M. Korenkov,
N. Poopalasingam,
M. Madler and
et al,
"Evaluation of a Rapid Antigen Test To Detect SARS-CoV-2 Infection and Identify Potentially Infectious Individuals",
J Clin Microbiol,
vol. 59,
no. 9,
2021.
| DOI: | 10.1128/JCM.00896-21 |
T. Toptana,
L. Eckermann,
A. E. Pfeiffer and
et al,
"Evaluation of a SARS-CoV-2 rapid antigen test: Potential to help reduce community spread?",
J Clin Virol,
vol. 135,
2021.
| DOI: | 10.1016/j.jcv.2020.104713 |
M. Metzendorf and
R. M. Featherstone,
"Evaluation of the comprehensiveness, accuracy and currency of the Cochrane COVID-19 Study Register for supporting rapid evidence synthesis production",
Res Synth Methods,
Jun.
2021.
| DOI: | 10.1002/jrsm.1501 |
J. Hildebrandt,
M. I. Metzendorf and
T. Jakob,
"Evaluierung der deutschen Datenbank Current Contents Medizin (CC MED) als potenzielle Datenquelle für das Cochrane COVID-19-Studienregister",
GMS Med Inform Biom Epidemiol,
vol. 17,
no. 3,
pp. Doc12,
2021.
| DOI: | 10.3205/mibe000226 |
| Datei: |
[en]
J. M. Kruse,
D. Zickler,
W. M. Lüdemann,
S. K. Piper,
I. Gotthardt,
J. Ihlow,
S. Greuel,
D. Horst,
A. Kahl,
K. Eckardt and
S. Elezkurtaj,
"Evidence for a thromboembolic pathogenesis of lung cavitations in severely ill COVID-19 patients",
Scientific Reports,
vol. 11,
no. 1,
pp. 16039,
Aug.
2021.
| DOI: | 10.1038/s41598-021-95694-0 |
| Datei: | https://www.nature.com/articles/s41598-021-95694-0 |
M. Popp,
P. Kranke,
P. Meybohm,
M. Metzendorf,
N. Skoetz,
M. S. Stegemann and
S. Weibel,
"Evidence on the efficacy of ivermectin for COVID-19: another story of apples and oranges",
BMJ Evid Based Med,
vol. 2021,
pp. bmjebm-2021-111791,
2021.
| DOI: | 10.1136/bmjebm-2021-111791 |
J. Wachinger,
M. Schirmer,
N. Täuber and
et al,
"Experiences with opt-in, at-home screening for SARS-CoV-2 at a primary school in Germany: an implementation study",
BMJ Paediatr Open,
vol. 5,
no. 1,
2021.
| DOI: | 10.1136/bmjpo-2021-001262 |
| Datei: | https://doi.org/10.1136/bmjpo-2021-001262 |
[en]
J. M. Tielker,
J. P. Weber,
S. T. Simon,
C. Bausewein,
S. Stiel and
N. Schneider,
"Experiences, challenges and perspectives for ensuring end-of-life patient care: A national online survey with general practitioners in Germany",
PLOS ONE,
vol. 16,
no. 7,
pp. e0254056,
Jul.
2021.
Abstract:
Background The SARS-CoV-2 (COVID-19) pandemic is posing major challenges for health care systems. In Germany, one such challenge has been that adequate palliative care for the severely ill and dying (with and without COVID-19), as well as their loved ones, has not been available at all times and in all settings., the pandemic has underlined the significance of the contribution of general practitioners (GPs) to the care of severely ill and dying patients. Objectives To describe GPs’ experiences, challenges and perspectives with respect to end-of-life care during the first peak of the pandemic (spring 2020) in Germany. Materials and methods In November and December 2020, a link to an Unipark online survey was sent to GPs registered on nationwide distribution lists. Results In total, 410 GPs responded; 61.5% indicated that the quality of their patients’ end-of-life care was maintained throughout the pandemic, 36.8% reported a decrease in quality compared to pre-pandemic times. Of the GPs who made home visits to severely ill and dying patients, 61.4% reported a stable number of visits, 28.5% reported fewer visits. 62.7% of the GPs reported increased telephone contact and reduced personal contact with patients; 36.1% offered video consultations in lieu of face-to-face contact. The GPs reported that relatives were restricted (48.5%) or prohibited from visiting (33.4%) patients in nursing homes. They observed a fear of loneliness among patients in nursing homes (91.9%), private homes (87.3%) and hospitals (86.1%). Conclusions The present work provides insights into the pandemic management of GPs and supports the development of a national strategy for palliative care during a pandemic. To effectively address end-of-life care, GPs and palliative care specialists should be involved in COVID-19 task forces on micro, meso and macro levels of health care.
| DOI: | 10.1371/journal.pone.0254056 |
| Datei: | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0254056 |
Abstract:
Background The SARS-CoV-2 (COVID-19) pandemic is posing major challenges for health care systems. In Germany, one such challenge has been that adequate palliative care for the severely ill and dying (with and without COVID-19), as well as their loved ones, has not been available at all times and in all settings., the pandemic has underlined the significance of the contribution of general practitioners (GPs) to the care of severely ill and dying patients. Objectives To describe GPs’ experiences, challenges and perspectives with respect to end-of-life care during the first peak of the pandemic (spring 2020) in Germany. Materials and methods In November and December 2020, a link to an Unipark online survey was sent to GPs registered on nationwide distribution lists. Results In total, 410 GPs responded; 61.5% indicated that the quality of their patients’ end-of-life care was maintained throughout the pandemic, 36.8% reported a decrease in quality compared to pre-pandemic times. Of the GPs who made home visits to severely ill and dying patients, 61.4% reported a stable number of visits, 28.5% reported fewer visits. 62.7% of the GPs reported increased telephone contact and reduced personal contact with patients; 36.1% offered video consultations in lieu of face-to-face contact. The GPs reported that relatives were restricted (48.5%) or prohibited from visiting (33.4%) patients in nursing homes. They observed a fear of loneliness among patients in nursing homes (91.9%), private homes (87.3%) and hospitals (86.1%). Conclusions The present work provides insights into the pandemic management of GPs and supports the development of a national strategy for palliative care during a pandemic. To effectively address end-of-life care, GPs and palliative care specialists should be involved in COVID-19 task forces on micro, meso and macro levels of health care.
J. M. Tielker,
J. Weber,
S. T. Simon,
C. Bausewein,
S. Stiel and
N. Schneider,
"Experiences, challenges and perspectives for ensuring end-of-life patient care: A national online survey with general practitioners in Germany",
PLoS ONE,
vol. 16,
no. 7,
pp. e0254056,
2021.
| DOI: | 10.1371/journal.pone.0254056 |
K. Subbarayan,
K. Ulagappan,
C. Wickenhauser and
B. Seliger,
"Expression and Clinical Significance of SARS-CoV-2 Human Targets in Neoplastic and Non-Neoplastic Lung Tissues",
Current Cancer Drug Targets,
vol. 21,
no. 5,
pp. 428—442,
Jul.
2021.
| DOI: | 10.2174/1568009620666201207145019 |
| Datei: | https://www.eurekaselect.com/article/112117 |
[en]
T. Hansen,
U. Titze,
N. S. A. Kulamadayil-Heidenreich,
S. Glombitza,
J. J. Tebbe,
C. Röcken,
B. Schulz,
M. Weise and
L. Wilkens,
"First case of postmortem study in a patient vaccinated against SARS-CoV-2",
International Journal of Infectious Diseases,
vol. 107,
pp. 172—175,
Jun.
2021.
| DOI: | 10.1016/j.ijid.2021.04.053 |
| Datei: | https://www.sciencedirect.com/science/article/pii/S1201971221003647 |
[Deutsch]
P. Michel,
G. Savinsky,
B. Ondruschka and
I. Czinczoll,
"Folgen einer Reanimation in Zeiten der Pandemie",
Hamburger Ärzteblatt,
vol. 2021,
no. 11,
pp. 28—30,
2021.
| Datei: | https://fis-uke.de/portal/de/publications/folgen-einer-reanimation-in-zeiten-der-pandemie(943a98ca-7e65-4bc3-abeb-f520157640a7).html |
M. Muenchhoff,
A. Graf,
S. Krebs and
et al,
"Genomic epidemiology reveals multiple introductions of SARS-CoV-2 followed by community and nosocomial spread, Germany, February to May 2020",
Euro Surveill,
vol. 26,
no. 43,
2021.
| DOI: | 10.2807/1560-7917.ES.2021.26.43.2002066 |
| Datei: | https://doi.org/10.2807/1560-7917.ES.2021.26.43.2002066 |
S. Thun,
J. Sass and
A. Bartschke,
"German Corona Consensus Datensatz (GECCO): Verbesserter Austausch von COVID-19-Forschungsdaten",
kma - Klinik Management aktuell,
vol. 26,
no. 06,
pp. 55—56,
2021.
| DOI: | 10.1055/s-0041-1731187 |
A. Gruber,
T. Firsching,
J. Trimpert and
K. Dietert,
"Hamster models of COVID-19 pneumonia reviewed: How human can they be?",
Vet Pathol,
2021.
[en]
F. Olearo,
D. Nörz,
F. Heinrich,
J. P. Sutter,
K. Roedl,
A. Schultze,
J. Wiesch,
P. Braun,
L. Oestereich,
B. Kreuels,
D. Wichmann,
M. Aepfelbacher,
S. Pfefferle and
M. Lütgehetmann,
"Handling and accuracy of four rapid antigen tests for the diagnosis of SARS-CoV-2 compared to RT-qPCR",
Journal of Clinical Virology,
vol. 137,
pp. 104782,
Apr.
2021.
| DOI: | 10.1016/j.jcv.2021.104782 |
| Datei: | https://www.sciencedirect.com/science/article/pii/S1386653221000494 |
M. Schmidt,
S. Kugai and
B. Weltermann,
"Handlungsfähigkeit von Hausärzt*innen während der COVID-19-Pandemie",
DocV-15-05,
2021.
| DOI: | 10.3205/21degam086 |
J. A. F. Klein,
L. J. Krüger,
F. Tobian and
et al,
"Head-to-head performance comparison of self-collected nasal versus professional-collected nasopharyngeal swab for a WHO-listed SARS-CoV-2 antigen-detecting rapid diagnostic test",
Med Microbiol Immunol,
vol. 210,
no. 4,
2021.
| DOI: | 10.1007/s00430-021-00710-9 |
| Datei: | https://doi.org/10.1007/s00430-021-00710-9 |
S. Hadzibegovic,
A. Lena,
T. Churchill,
J. Ho,
S. Potthoff,
C. Denecke,
L. Rösnick,
K. Heim,
M. Kleinschmidt,
L. Sander and
D. Stahl,
"Heart failure with preserved ejection fraction according to the HFA-PEFF score in COVID-19 patients: clinical correlates and echocardiographic findings",
Eur J Heart Fail,
vol. 23,
no. 11,
pp. 1891—1902,
2021.
| DOI: | 10.1002/ejhf.2210 |
[en]
B. Kaltschmidt,
A. D. E. Fitzek,
J. Schaedler,
C. Förster,
C. Kaltschmidt,
T. Hansen,
F. Steinfurth,
B. A. Windmöller,
C. Pilger,
C. Kong,
K. Singh,
A. Nierhaus,
D. Wichmann,
J. Sperhake,
K. Püschel,
T. Huser,
M. Krüger,
S. C. Robson,
L. Wilkens and
J. Esch,
"Hepatic Vasculopathy and Regenerative Responses of the Liver in Fatal Cases of COVID-19",
Clinical Gastroenterology and Hepatology,
vol. 19,
no. 8,
pp. 1726—1729.e3,
Aug.
2021.
| DOI: | 10.1016/j.cgh.2021.01.044 |
| Datei: | https://www.sciencedirect.com/science/article/pii/S154235652100094X |
R. Groß and
et al,
"Heterologous ChAdOx1 nCoV-19 and BNT162b2 prime-boost vaccination elicits potent neutralizing antibody responses and T cell reactivity against prevalent SARS-CoV-2 variants",
EBioMedicine,
vol. 75,
pp. 103761,
2021.
| DOI: | 10.1016/j.ebiom.2021.103761 |
M. Tenbusch,
S. Schumacher,
E. Vogel and
et al,
"Heterologous prime–boost vaccination with ChAdOx1 nCoV-19 and BNT162b2",
Lancet Infect Dis,
vol. 21,
no. 9,
2021.
| DOI: | 10.1016/S1473-3099(21)00420-5 |
M. Rössler,
J. Jacob,
L. Risch,
F. Tesch,
D. Enders,
D. Wende,
R. Jucknewitz,
O. Weidinger,
M. Batram,
P. Ballesteros,
S. Baßler,
D. Hertle,
U. Repschläger,
N. Richter,
C. Schulte,
A. Schramm,
F. Sobik,
M. Treskova-Schwarzbach,
S. Scholz,
J. Walker and
D. Stahl,
"Hierarchisierung von Risikofaktoren für schwere COVID-19-Erkrankungsverläufe im Kontext der COVID-19-Schutzimpfungen",
2021.
| DOI: | 10.25646/8405.2 |
M. Lehmann,
C. Heldt,
J. Meinhardt,
F. Schmidt and
e. a. Rodriguez-Sillke,
"Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8(+) T cells",
Mucosal Immunol,
vol. 14,
pp. 1381—1392,
2021.
M. Lehmann,
C. Heldt and
et al,
"Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8+ T cells",
Mucosal Immunol,
pp. 1-12,
2021.
| DOI: | 10.1038/s41385-021-00437-z |
[en]
M. Lehmann,
K. Allers,
C. Heldt,
J. Meinhardt,
F. Schmidt,
Y. Rodriguez-Sillke,
D. Kunkel,
M. Schumann,
C. Böttcher,
C. Stahl-Hennig,
S. Elezkurtaj,
C. Bojarski,
H. Radbruch,
V. M. Corman,
T. Schneider,
C. Loddenkemper,
V. Moos,
C. Weidinger,
A. A. Kühl and
B. Siegmund,
"Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8+ T cells",
Mucosal Immunology,
vol. 14,
no. 6,
pp. 1381—1392,
Nov.
2021.
| DOI: | 10.1038/s41385-021-00437-z |
| Datei: | https://www.sciencedirect.com/science/article/pii/S1933021922002318 |
J. Barros-Martins,
S. I. Hammerschmidt and
A. Cossmann,
"Humoral and cellular immune response against SARS-CoV-2 variants following heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination",
MedRxiv,
2021.
| DOI: | 10.1101/2021.06.01.21258172 |
| Datei: | https://doi.org/10.1101/2021.06.01.21258172 |