Publikationen im NUM
Hier finden Sie eine Liste der Publikationen, die im Zusammenhang mit dem Netzwerk Universitätsmedizin in der ersten und zweiten Förderphase entstanden sind.
S. Einhauser,
D. Peterhoff,
H. H. Niller and
et al,
"Spectrum bias and individual strengths of SARS-CoV-2 serological tests—A population-based evaluation",
Diagnostics,
vol. 11,
no. 10,
2021.
| DOI: | 10.3390/diagnostics11101843 |
| Datei: | https://doi.org/10.3390/diagnostics11101843 |
M. Borsche,
A. Balck and
et al,
"Spreading of SARS-CoV-2 Among Adult Asylum Seekers in Refugee Shelters in Germany",
Lancet,
2021.
| DOI: | 10.2139/ssrn.3889435 |
M. Geraedts,
M. Eberlein-Gonska,
R. Hecker,
K. Schneider,
I. Schroeder-Printzen and
M. Zeuner,
"Stationäre Versorgung: Empfehlungen für ein künftiges Pandemiemanagement",
Dtsch Arztebl International,
vol. 118,
no. 19—20,
pp. A-991,
2021.
C. R. Torres Reyes,
E. Steinmann,
N. Timmesfeld and
et al,
"Students in Dormitories were not major drivers of the pandemic during winter term 2020/2021: A cohort study with RT-PCR and antibody surveillance in a German university city",
COVID,
vol. 1,
no. 1,
2021.
| DOI: | 10.3390/covid1010029 |
S. Warnat-Herresthal and
et al,
"Swarm Learning for decentralized and confidential clinical machine learning",
Nature,
2021.
| DOI: | 10.1038/s41586-021-03583-3 |
T. Hempel and
et al,
"Synergistic inhibition of SARS-CoV-2 cell entry by otamixaban and covalent protease inhibitors: pre-clinical assessment of pharmacological and molecular properties",
Chemical Science,
vol. 12,
pp. 12600–12609,
2021.
| DOI: | 10.1039/D1SC01494C |
C. Wagner,
M. Griesel,
A. Mikolajewska,
A. Mueller,
M. Nothacker,
K. Kley,
M. Metzendorf,
A. Fischer,
M. Kopp,
M. Stegemann,
N. Skoetz and
F. Fichtner,
"Systemic corticosteroids for the treatment of COVID-19",
Cochrane Database of Systematic Reviews,
vol. 2021,
pp. CD014963,
2021.
| DOI: | 10.1002/14651858.CD014963 |
M. O'Hare,
H. A. B. Whitmore,
C. Marino,
L. Ramos,
S. Delgado-Tirado,
X. Hu,
N. Chmielewska,
A. Chandrahas and
D. Stahl,
"Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators",
Am J Pathol,
vol. 191,
no. 7,
pp. 1193-1208,
2021.
| DOI: | 10.1016/j.ajpath.2021.04.006 |
M. Baldinger,
A. Heinrich,
E. Martens,
M. Dommasch,
A. Muller,
A. Siegmann,
G. Schmidt and
K. V. Laerhoven,
"TELECOVID: Remote Vital Signs Monitoring of COVID-19 Risk Patients in Home Isolation With an In-Ear Wearable",
IEEE Pervasive Computing,
vol. 20,
no. 2,
pp. 58—62,
2021.
| DOI: | 10.1109/MPRV.2021.3066825 |
G. Nouailles,
E. Wyler,
P. Pennitz,
D. Postmus,
D. Vladimirova,
J. Kazmierski,
F. Pott,
K. Dietert,
M. Muelleder,
V. Farztdinov and
D. Stahl,
"Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19",
Nat Commun,
vol. 12,
no. 1,
pp. 4869,
2021.
| DOI: | 10.1038/s41467-021-25030-7 |
G. Nouailles,
E. Wyler,
P. Pennitz,
D. Postmus,
D. Vladimirova and
e. a. Kazmierski,
"Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19",
Nat Commun,
vol. 12,
pp. 4869,
2021.
| DOI: | 10.1038/s41467-021-25030-7 |
G. Nouailles,
E. Wyler,
P. Pennitz,
D. Postmus,
D. Vladimirova,
J. Kazmierski,
F. Pott,
K. Dietert,
M. Muelleder,
V. Farztdinov,
B. Obermayer,
B. Sawitzki,
C. Drosten,
L. E. Sander,
N. Suttorp,
M. Ralser,
D. Beule,
A. Gruber,
C. Goffinet,
M. Landthaler,
J. Trimpert,
M. Witzenrath,
S. Wienhold and
T. Hoefler,
"Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19",
Nat Commun.2021;12(1):4869,
2021.
L. Krüger,
M. Gaeddert,
F. Tobian and
D. Stahl,
"The Abbott PanBio WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test for SARS-CoV-2—Evaluation of the accuracy and ease-of-use",
PLOS ONE,
vol. 16,
no. 5,
2021.
| DOI: | 10.1371/journal.pone.0247918 |
| Datei: | https://doi.org/10.1371/journal.pone.0247918 |
M. Witzenrath and
W. Kuebler,
"The CypA-netics of Ventilator-induced Lung Injury",
Am J Respir Crit Care Med,
vol. 204,
no. 4,
pp. 385—387,
2021.
| DOI: | 10.1164/rccm.202104-0919ED |
M. Witzenrath and
W. Kuebler,
"The CypA-netics of Ventilator-induced Lung Injury. Am J Respir Crit Care Med",
204(4):385-387,
2021.
C. Ramirez Alvarez,
C. Kee,
A. K. Sharma,
L. Thomas,
F. I. Schmidt and
e. a. Stanifer,
"The endogenous cellular protease inhibitor SPINT2 controls SARS-CoV-2 viral infection and is associated with disease severity",
PLOS Pathogens,
vol. 17,
no. 5,
pp. e1009687,
2021.
| DOI: | 10.1371/journal.ppat.1009687 |
F. Hornung,
J. Rogal,
P. Loskill,
B. Löffler and
S. Deinhardt-Emmer,
"The Inflammatory Profile of Obesity and the Role on Pulmonary Bacterial and Viral Infections",
Int J Mol Sci,
vol. 22,
2021.
V. Clemens,
P. Beschoner,
M. Jarczok,
K. Weimer,
M. Kempf,
E. Morawa,
F. Geiser,
S. Steudte-Schmiedgen,
H. Gündel,
J. Fegert and
L. Jerg-Bretzke,
"The mediating role of COVID-19-related burden in the association between adverse childhood experiences and emotional exhaustion: Results of the egePan–VOICE study",
European Journal of Psychotraumatology,
vol. 12,
no. 1,
pp. 1976441,
2021.
| DOI: | 10.1080/20008198.2021.1976441 |
M. Hoffmann and
et al,
"The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic",
Cell,
2021.
| DOI: | 10.1016/j.cell.2021.12.032 |
J. Wachinger,
I. D. Olaru,
S. Horner and
et al,
"The potential of SARS-CoV-2 antigen-detection tests in the screening of asymptomatic persons",
Clin Microbiol Infect,
vol. 27,
no. 11,
2021.
| DOI: | 10.1016/j.cmi.2021.07.020 |
| Datei: | https://doi.org/10.1016/j.cmi.2021.07.020 |
[en]
H. Bösmüller,
M. Matter,
F. Fend and
A. Tzankov,
"The pulmonary pathology of COVID-19",
Virchows Archiv,
vol. 478,
no. 1,
pp. 137—150,
Jan.
2021.
| DOI: | 10.1007/s00428-021-03053-1 |
| Datei: | https://doi.org/10.1007/s00428-021-03053-1 |
I. Panchyrz,
S. Pohl,
J. Hoffmann,
C. Gatermann,
F. Walther,
L. Harst,
H. Held,
C. Kleber and
J. Schmitt,
"The role of university hospitals in regional health care management for coping with the COVID-19 pandemic",
Zeitschrift Für Evidenz, Fortbildung Und Qualität Im Gesundheitswesen,
vol. 167,
pp. 68—77,
2021.
| DOI: | 10.1016/j.zefq.2021.09.004 |
J. Wenzel,
J. Lampe,
H. Müller-Fielitz and
et al,
"The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells",
Nat Neurosci,
vol. 24,
no. 11,
pp. 1522-1533,
2021.
| DOI: | 10.1038/s41593-021-00926-1 |
K. Kitazawa,
S. Deinhardt-Emmer,
T. Inomata,
S. Deshpande and
C. Sotozono,
"The Transmission of SARS-CoV-2 Infection on the Ocular Surface and Prevention Strategies",
Cells,
vol. 10,
2021.
H. Meyer,
N. Bailis and
A. Surov,
"Time efficiency and reliability of established computed tomographic obstruction scores in patients with acute pulmonary embolism",
PloS one,
vol. 16,
no. 12,
pp. e0260802,
2021.
Abstract:
Acute pulmonary embolism (PE) is a life-threatening disease with a high mortality. Computed tomographic pulmonary angiography (CTPA) is used in clinical routine for diagnosis of PE. Many pulmonary obstruction scores were proposed to aid in stratifying clinical course of PE. The purpose of the present study was to compare common pulmonary obstruction scores in PE in regard of time efficiency and interreader agreement based upon a representative patient sample. Overall, 50 patients with acute PE were included in this single center, retrospective analysis. Two readers scored the CT images blinded to each other and assessed the scores proposed by Mastora et al., Qanadli et al., Ghanima et al. and Kirchner et al. The required time was assessed of each reading for scoring. For reader 1, Mastora score took the longest time duration, followed by Kirchner score, Qanadli score and finally Ghanima score (every test, p<0.0001). The interreader variability was excellent for all scores with no significant differences between them. In the Spearman's correlation analysis strong correlations were identified between the scores of Mastora, Qanadli and Kirchner, whereas Ghanima score was only moderately correlated with the other scores. There was a weak correlation between time duration and Mastora score (r = 0.35, p = 0.014). For the Ghanima score, a significant inverse correlation was found (r = -0.67, p<0.0001). For the investigated obstruction scores, there are significant differences in regard of time consumption with no relevant differences in regard of interreader variability in patients with acute pulmonary embolism. Mastora score requires the most time effort, whereas the score by Ghanima the least time.
| DOI: | 10.1371/journal.pone.0260802 |
| Datei: | https://pubmed.ncbi.nlm.nih.gov/34860827/ |
Abstract:
Acute pulmonary embolism (PE) is a life-threatening disease with a high mortality. Computed tomographic pulmonary angiography (CTPA) is used in clinical routine for diagnosis of PE. Many pulmonary obstruction scores were proposed to aid in stratifying clinical course of PE. The purpose of the present study was to compare common pulmonary obstruction scores in PE in regard of time efficiency and interreader agreement based upon a representative patient sample. Overall, 50 patients with acute PE were included in this single center, retrospective analysis. Two readers scored the CT images blinded to each other and assessed the scores proposed by Mastora et al., Qanadli et al., Ghanima et al. and Kirchner et al. The required time was assessed of each reading for scoring. For reader 1, Mastora score took the longest time duration, followed by Kirchner score, Qanadli score and finally Ghanima score (every test, p<0.0001). The interreader variability was excellent for all scores with no significant differences between them. In the Spearman's correlation analysis strong correlations were identified between the scores of Mastora, Qanadli and Kirchner, whereas Ghanima score was only moderately correlated with the other scores. There was a weak correlation between time duration and Mastora score (r = 0.35, p = 0.014). For the Ghanima score, a significant inverse correlation was found (r = -0.67, p<0.0001). For the investigated obstruction scores, there are significant differences in regard of time consumption with no relevant differences in regard of interreader variability in patients with acute pulmonary embolism. Mastora score requires the most time effort, whereas the score by Ghanima the least time.
M. R. Muzoora and
et al,
"Towards FAIR Patient Reported Outcome: Application of the Interoperability Principle for Mobile Pandemic Apps",
Stud Health Technol Inform,
vol. 287,
pp. 85—86,
2021.
| DOI: | 10.3233/SHTI210315 |
A. Wulff,
P. Biermann,
T. Landesberger,
T. Baumgartl,
C. Schmidt,
A. Y. Alhaji,
K. Schick,
P. Waldstein,
Y. Zhu,
H. I. C. S. Group,
D. Krefting,
S. Scheithauer and
M. Marschollek,
"Tracing COVID-19 Infection Chains Within Healthcare Institutions – Another Brick in the Wall Against SARS-CoV-2",
Studies in Health Technology and Informatics,
2021.
| DOI: | 10.3233/SHTI220168 |
| Datei: | https://doi.org/10.3233/SHTI220168 |
A. Wulff,
P. Biermann,
T. von Landesberger,
T. Baumgartl,
C. Schmidt,
A. Alhaji,
K. Schick,
P. Waldstein,
Y. Zhu,
HiGHmed Infection Control Study Group,
D. Krefting,
S. Scheithauer and
M. Marschollek,
"Tracing COVID-19 infection chains within healthcare institutions: Another brick in the wall against SARS-CoV-2",
Studies in Health Technology and Informatics,
vol. 290: MEDINFO 2021: One World, One Health – Global,
pp. 699 - 703,
2021.
| DOI: | 10.3233/SHTI220168 |
| Datei: | https://imia-medinfo.org/medinfo21/ |
A. Wulff,
P. Biermann,
T. von Landesberger,
T. Baumgartl,
C. Schmidt,
A. Alhaji,
K. Schick,
P. Waldstein,
Y. Zhu,
HiGHmed Infection Control Study Group,
D. Krefting,
S. Scheithauer and
M. Marschollek,
"Tracing COVID-19 infection chains within healthcare institutions: Another brick in the wall against SARS-CoV-2",
Studies in Health Technology and Informatics,
vol. 290: MEDINFO 2021: One World, One Health – Global,
pp. 699 - 703,
2021.
| DOI: | 10.3233/SHTI220168 |
E. Wyler,
K. Mosbauer,
V. Franke,
A. Diag,
L. T. Gottula and
e. a. Arsie,
"Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy",
iScience,
vol. 24,
pp. 102151,
2021.
| DOI: | 10.1016/j.isci.2021.102151 |
[Deutsch]
M. Verhoff,
K. Püschel and
B. Ondruschka,
"Über die Ansteckungsgefahr beim Umgang mit SARS-CoV-2-positiven Leichen",
Bestattungskultur,
no. 5,
pp. 24—28,
2021.
| Datei: | https://fis-uke.de/portal/de/publications/uber-die-ansteckungsgefahr-beim-umgang-mit-sarscov2positiven-leichen(a5affc27-e329-4aa4-8a39-566dbe2728c7).html |
I. Backhaus,
D. Hermsen,
J. Timm,
F. Boege,
N. Lübke,
K. Göbels,
D. Lieth and
N. Dragano,
"Under-ascertainment of COVID-19 cases among first responders: a seroepidemiological study",
Occupational Medicine,
pp. kqab164,
2021.
| DOI: | 10.1093/occmed/kqab164 |
S. Schuster,
J. Lisack,
I. Subota,
H. Zimmermann,
C. Reuter and
e. a. Mueller,
"Unexpected plasticity in the life cycle of Trypanosoma brucei",
Elife,
vol. 10,
2021.
| DOI: | 10.7554/eLife.62090 |
C. Klinger,
J. Burns,
A. Movsisyan,
R. Biallas,
S. L. Norris,
J. E. Rabe,
J. M. Stratil,
S. Voss,
K. Wabnitz,
E. Rehfuess and
B. Verboom,
"Unintended health and societal consequences of international travel measures during the COVID-19 pandemic: A scoping review",
J Travel Med,
2021.
| DOI: | 10.1093/jtm/taab123 |
M. Witkowski and
et al,
"Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells",
Nature,
2021.
| DOI: | 10.1038/s41586-021-04142-6 |
M. Witkowski,
C. Tizian,
M. Ferreira-Gomes and
et al,
"Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells",
Nature,
vol. 600,
no. 7888,
pp. 295-301,
2021.
| DOI: | 10.1038/s41586-021-04142-6 |
M. Witkowski,
C. Tizian,
M. Ferreira-Gomes,
D. Niemeyer,
T. C. Jones and
e. a. Heinrich,
"Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells",
Nature,
2021.
| DOI: | 10.1038/s41586-021-03859-9 |
[German]
S. Berezowska,
P. Boor,
D. Jonigk and
V. Tischler,
"Update on thoracic pathology 2021-report of the working group thoracic pathology of the German Society of Pathology",
Pathologe,
pp. 1-4,
2021.
| DOI: | 10.1007/s00292-021-00991-0 |
[en]
C. Dittmayer,
J. Meinhardt,
H. Radbruch,
J. Radke,
B. I. Heppner,
F. L. Heppner,
W. Stenzel,
G. Holland and
M. Laue,
"Using EM data to understand COVID-19 pathophysiology – Authors' reply",
The Lancet,
vol. 397,
no. 10270,
pp. 197—198,
Jan.
2021.
| DOI: | 10.1016/S0140-6736(21)00032-5 |
| Datei: | https://www.sciencedirect.com/science/article/pii/S0140673621000325 |
O. Gross,
O. Moerer,
T. Rauen and
et al,
"Validation of a Prospective Urinalysis-Based Prediction Model for ICU Resources and Outcome of COVID-19 Disease: A Multicenter Cohort Study",
J Clin Med,
vol. 10,
no. 14,
2021.
| DOI: | 10.3390/jcm10143049 |
L. Nicolai,
A. Leunig,
S. Brambs,
R. Kaiser,
M. Joppich,
M. Hoffknecht,
C. Gold,
A. Engel,
V. Polewka,
M. Muenchhoff and
D. Stahl,
"Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID-19 from influenza pneumonia",
J Thromb Haemost,
vol. 19,
no. 2,
pp. 574-581,
2021.
| DOI: | 10.1111/jth.15179 |
K. Roedl,
S. Heidenreich,
S. Pfefferle,
D. Jarczak,
T. T. Urbanowicz,
D. Nörz,
N. Kröger,
S. Kluge,
M. Lütgehetmann,
M. Christopeit and
D. Wichmann,
"Viral Dynamics of SARS-CoV-2 in Critically Ill Allogeneic Hematopoietic Stem Cell Transplant Recipients and Immunocompetent Patients with COVID-19",
Am J Respir Crit Care Med,
vol. 203,
no. 2,
pp. 242-245,
2021.
K. Roedl,
S. Heidenreich,
S. Pfefferle,
D. Jarczak,
T. T. Urbanowicz,
D. Nörz,
M. Aepfelbacher,
N. Kröger,
S. Kluge,
M. Lütgehetmann,
M. Christopeit and
D. Wichmann,
"Viral Dynamics of SARS-CoV-2 in Critically Ill Allogeneic Hematopoietic Stem Cell Transplant Recipients and Immunocompetent Patients with COVID-19",
American Journal of Respiratory and Critical Care Medicine,
vol. 203,
no. 2,
pp. 242—245,
Jan.
2021.
| DOI: | 10.1164/rccm.202009-3386LE |
| Datei: | https://www.atsjournals.org/doi/10.1164/rccm.202009-3386LE |
J. K. Stroehlein,
J. Wallqvist,
C. Iannizzi,
A. Mikolajewska,
M. Metzendorf,
C. Benstoem,
P. Meybohm,
M. Becker,
N. Skoetz,
M. Stegemann and
V. Piechotta,
"Vitamin D supplementation for the treatment of COVID-19: a living systematic review",
Cochrane Database of Systematic Reviews,
vol. 2021,
pp. CD015043,
2021.
| DOI: | 10.1002/14651858.CD015043 |
S. Weigang,
J. Fuchs,
G. Zimmer and
et al,
"Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants",
Nat Commun,
vol. 12,
no. 1,
2021.
| DOI: | 10.1038/s41467-021-26602-3 |
| Datei: | https://doi.org/10.1038/s41467-021-26602-3 |
D. Eggers,
"Best practice models for nursing care in the COVID-19-pandemic: a web-based survey. Joint Scientific Summer Conference DGP/EANS. Lessons learned from the pandemic in different nursing settings. 02.07.2021. Vortrag.",
2021.
M. Metzendorf,
J. Hildebrandt,
T. Jakob and
R. M. Featherstone,
"Das Cochrane COVID-19 Studienregister – eine studienbasierte, strukturierte Datenbank zur effizienten Identifizierung wissenschaftlicher Evidenz"
in Vortrag. 22. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin,
2021.
M. Winter and
et al,
"Exploring the Usability of the German COVID-19 Contact Tracing App in a Combined Eye Tracking and Retrospective Think Aloud Study"
in 2021 43rd Annual International Conference of the IEEE Engineering in Medicine & Biology Society,
2021,
pp. 2215—2221.
| DOI: | 10.1109/EMBC48546.2021.9630667 |
M. Lowin and
D. Kellner,
"From Twitter to COVID-19: Using NLP to Predict COVID-19 Infections"
in PACIS 2021 Proceedings,
2021.
F. Beierle and
et al,
"Public Perception of the German COVID-19 Contact-Tracing App Corona-Warn-App"
in 2021 IEEE 34th International Symposium on Computer-Based Medical Systems,
2021,
pp. 342—347.
| DOI: | 10.1109/CBMS52030.2021.00120 |