Publikationen im NUM

Fiedler-Lacombe L, Heim E, Valentin H, Rau H, Blumentritt A, Stahl D, Kraus M, Lorenz-Depiereux B. Herausforderungen des Einwilligungsmanagements von Minderjährigen bei Kohortenstudien. 16. DVMD-Fachtagung. 2022 05 12.

Rau H, Blumentritt A, Stahl D. Unabhängige Treuhandstelle der Universitätsmedizin Greifswald K.d.ö.R. Qualitätsgesichertes Management von Einwilligungserklärungen – Ein Appell zur Nutzung elektronischer Einwilligungserhebungen für zeitkritische klinische Forschung. 16. DVMD-Fachtagung. 2022 05 12.

Heim E, Valentin H, Rau H, Blumentritt A, Stahl D, Stecher M, Kraus M, Lorenz-Depiereux B. Widerrufs- und Ausschlussmanagement unter Berücksichtigung komplexer Konstellationen in der COVID-19-Forschung am Beispiel NUM. 16. DVMD-Fachtagung. 2022 05 12.

Hopff S, Tilch K, Kraus M, Lorenz-Depiereux B, Anton G, Appel K, Bahmer T, Bartschke A, Bellinghausen C, Bernemann I, Brechtel M, Brünn C, Fiessler C, Geisler R, Hansch S, Hanses F, Hanß S, Heyder R, Hoffmann A, Horn A, Jakob C, Jiru-Hillmann S, Keil T, Khodamoradi Y, Kohls M, Krefting D, Kunze S, Kurth F, Lieb W, Lippert LJ, Lorbeer R, Lysyakova L, Maetzler C, Miljukov O, Nauck M, Pilgram L, Püntmann V, Reese J, Reinke L, Rudolph S, Sass J, Schäfer C, Schaller J, Schattschneider M, Scheer C, Scherer M, Schmidt J, Schmidt S, Schons M, Seibel K, Stahl D, Stecher M, Steinbeis F, Störk S, Tauchert M, Thibeault C, Töpfner N, Ungethüm K, Valentin H, Wiedmann S, Zoller T, Berner R, Krawczak M, Nagel E, Illig T, Schreiber S, Witzenrath M, Heuschmann P, Vehreschild JJ. Ethical and coordinative challenges in setting up a national cohort study exemplified by the German National Pandemic Cohort Network (NAPKON). Oral presentation Kongress ECCMID 04/2022. 2022 04.

Stahl D. Vollelektronische Erfassung von Einwilligungen (Informed Consents) mittels Tablets. Lohfert – Preis.. 2022 02 28. (https://www.christophlohfert-stiftung.de/panorama/ausschreibung-fuer-den-lohfert-preis-2022-beendet/):

Triefenbach L, Otto R, Bienzeisler J, Kombeiz A, Saskia E, Röhrig R, Majeed RW, Aktin Research Group . Establishing a data quality baseline in the AKTIN Emergency Department Data Registry – A secondary use perspective. Stud Health Technol Inform.. 2022 Mai 25; 294(25):209-213.      [DOI]  [Pubmed] 

Scheer C, Fiedler-Lacombe L, Stahl D, Nauck M, Hoffmann W, Schäfer E, Saljé K, Fritz A, Kohlmann T, Hübner N, Napp M, Rauch B, Völker U, Felix S, Lucchese G, Flöel A, Engeli S, Hahnenkamp K, Tzvetkov M. Course of disease and risk factors for hospitalization in outpatients with a SARS‑CoV‑2 infection.. SCIENTIFIC REPORTS. (open access) 2022; 12(1):7249. 2022.

Schäfer E, Scheer C, Saljé K, Fritz A, Kohlmann T, Hübner N, Napp M, Fiedler-Lacombe L, Stahl D, Rauch B, Nauck M, Völker U, Felix S, Lucchese G, Flöel A, Engeli S, Hoffmann W, Hahnenkamp K, Tzvetkov M. Course of disease and risk factors for hospitalization in outpatients with a SARS‑CoV‑2 infection.. SCIENTIFIC REPORTS. (open access) 2022; 12(1):7249. 2022.

Tauchert M, Bernemann I, Kühn-Steven A, Kopfnagel V, Kunze S, Illig T, Anton G. Digital knowledge management within the NAPKON study.. Nationales Biobanken Symposium Abstract 11. 2022.

Kühnapfel A, Horn K, Klotz U, Kiehntopf M, Rosolowski M, Loeffler M, Ahnert P, Suttorp N, Witzenrath M, Scholz M. Genetic Regulation of Cytokine Response in Patients with Acute Community-Acquired Pneumonia. Genes (Basel).. 2022.

Dannebaum R, Suwalski P, Asgharian H, Du ZG, Weiner J, Holtgrewe M, Thibeault C, Müller M, Wang X, Saccomanno J, Doehn J, Hübner R, Suttorp N, Witzenrath M, Hippenstiel S, Sander LE, Kurth F, Group P, Lin H, Karadeniz Z, Hinzmann B, Blüher A, Siemann S, Telman D, Skurk C, Poller W, Beule D, Guettouche T, Landmesser U, Berka J, Luong K, Rubelt F, Heidecker B. Highly multiplexed immune repertoire sequencing links multiple lymphocyte classes with severity of response to COVID-19.. EClinicalMedicine.2022;48:101438. 2022.

Illig T. NAPKON- Eine Erfolgsgeschichte. Plenarvortrag, Nationales Biobanken Symposium. 2022.

Steinbeis F, Thibeault C, Doellinger F, Ring R, Mittermaier M, Ruwwe-Glösenkamp C, Alius F, Knape P, Meyer H, Lippert L, Helbig E, Temmesfeld B, Suttorp N, Sander LE, Kurth F, Penzkofer T, Witzenrath M, Zoller T, Grund D. Severity of respiratory failure and computed chest tomography in acute COVID-19 correlates with pulmonary function and respiratory symptoms after infection with SARS-CoV-2: An observational longitudinal study over 12 months.. Respir Med. 2022;191:106709.. 2022.

Koll C, Hopff S, Meurers T. Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients.. Sci Data 9, 776. 2022.      [DOI] 

Wang Z, Cryar A, Lemke O, Tober-Lau P, Ludwig D, Helbig E, Hippenstiel S, Sander L, Blake D, Lane C, others . A multiplex protein panel assay for severity prediction and outcome prognosis in patients with COVID-19: An observational multi-cohort study. EClinicalMedicine. 2022; 49101495.      [DOI] 

Demichev V, et al . A proteomic survival predictor for COVID-19 patients in intensive care. PLOS Digital Health. 2022; 1e0000007.      [DOI] 

Würstle S, Erber J, Hanselmann M, others . A telemedicine-guided self-collection approach for PCR-based SARS-CoV-2 testing: Comparative study. JMIR Formative Research. 2022; 6(1):      [DOI]      [Datei] 

Meng F, Kottlors J, Shahzad R, Liu H, Fervers P, Jin Y, Rinneburger M, Le D, Weisthoff M, Liu W, Ni M, Sun Y, An L, Huai X, Móré D, Giannakis A, Kaltenborn I, Bucher A, Maintz D, Zhang L, Thiele F, Li M, Perkuhn M, Zhang H, Persigehl T. AI support for accurate and fast radiological diagnosis of COVID-19: an international multicenter, multivendor CT study. Eur Radiol. 2022;      [DOI] 

Wygrecka M, Birnhuber A, Seeliger B, Michalick L, Pak O, Schultz A, Schramm F, Zacharias M, Gorkiewicz G, David S, Welte T, Schmidt J, Weissmann N, Schermuly R, Barreto G, Schaefer L, Markart P, Brack M, Hippenstiel S, Kurth F, Sander L, Witzenrath M, Kuebler W, Kwapiszewska G, Preissner K. Altered fibrin clot structure and dysregulated fibrinolysis contribute to thrombosis risk in severe COVID-19. Blood Adv. 2022; 6(3):1074—1087.      [DOI] 

Buhr L, Schicktanz S, Nordmeyer E. Attitudes Toward Mobile Apps for Pandemic Research Among Smartphone Users in Germany: National Survey. JMIR Mhealth Uhealth. 2022; 10(1):e31857.      [DOI] 

Schulz SR, et al . Augmented Neutralization of SARS-CoV-2 Omicron Variant by Boost Vaccination and Monoclonal Antibodies. European journal of immunology. 2022;      [DOI] 

Schmid B, Griesel M, Fischer A, Romero CS, Metzendorf M, Weibel S, Fichtner F. Awake Prone Positioning, High-Flow Nasal Oxygen and Non-Invasive Ventilation as Non-Invasive Respiratory Strategies in COVID-19 Acute Respiratory Failure: A Systematic Review and Meta-Analysis. J Clin Med. 2022; 11(2):391.      [DOI] 

Demleitner AF, Wolff A, Erber J, et al . Best practice approaches to outpatient management of people living with Parkinson's disease during the COVID-19 pandemic. J Neural Transm (Vienna). 2022; 129(11):1377-1385.      [DOI] 

Lingscheid T, Lippert L, Hillus D, Kruis T, Thibeault C, Helbig E, Tober-Lau P, Pfäfflin F, Müller-Redetzky H, Witzenrath M, Zoller T, Uhrig A, Opitz B, Suttorp N, Kramer T, Sander L, Stegemann M, Kurth F. Characterization of antimicrobial use and co-infections among hospitalized patients with COVID-19: a prospective observational cohort study. Infection. 2022; 50(6):1441—1452.      [DOI] 

Walker A, Houwaart T, Finzer P, Ehlkes L, Tyshaieva A, Damagnez M, Strelow D, Duplessis A, Nicolai J, Wienemann T, Tamayo T, Kohns Vasconcelos M, Hülse L, Hoffmann K, Lübke N, Hauka S, Andree M, Däumer MP, Thielen A, Kolbe-Busch S, Göbels K, Zotz R, Pfeffer K, Timm J, Dilthey AT. Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Clusters Based on Integrated Genomic Surveillance, Outbreak Analysis and Contact Tracing in an Urban Setting. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2022; 74(6):1039—1046.      [DOI] 

Schmidt M, Gebauer S, Bartholmes A, Kadioglu D, Kleesiek J, Hamm B, Vogl T, Penzkofer T, Bucher A, Storf H. CODEX Meets RACOON - A Concept for Collaborative Documentation of Clinical and Radiological COVID-19 Data. Stud Health Technol Inform. 2022;      [DOI] 

Dulovic A, et al . Comparative Magnitude and Persistence of Humoral SARS-CoV-2 Vaccination Responses in the Adult Population in Germany. Frontiers in Immunology. 2022; 13828053.      [DOI] 

Georg P, Astaburuaga-García R, Bonaguro L, Brumhard S, Michalick L, Lippert ea. Complement activation induces excessive T cell cytotoxicity in severe COVID-19. Cell. 2022; 185493—512.e425.

Brandner J, Boor P, Borcherding L, et al . Contamination of personal protective equipment during COVID-19 autopsies. Virchows Arch. 2022; 1-10.      [DOI] 

Mardiko AA, Heinemann S, Bludau A, Kaba HEJ, Leha A, Maltzahn N, Mutters NT, Leistner R, Mattner F, Scheithauer S. COVID-19 vaccination strategy for hospital staff in Germany: a cross-sectional study in March-April 2021. The Journal of hospital infection. 2022; 12687—92.      [DOI] 

Scheithauer S, Bludau A, Heinemann S, Anton M, Knolle P. COVID-19-Impfstrategien für Beschäftigte deutscher Kliniken: Ergebnisse einer Befragung von Leitungen der (Krankenhaus\hbox-)Hygiene im Rahmen des B-FAST-Projektes. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 2022; 65(12):1299—1306.      [DOI] 

Radbruch L, Bausewein C. Covid-19: Was die Palliativmedizin leisten kann. Rheinisches Ärzteblatt. 2022; (6):

Tober-Lau P, et al . Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections. Emerging infectious diseases. 2022; 28      [DOI] 

Meyer-Arndt L, et al . Cutting Edge: Serum but Not Mucosal Antibody Responses Are Associated with Pre-Existing SARS-CoV-2 Spike Cross-Reactive CD4+ T Cells following BNT162b2 Vaccination in the Elderly. Journal of immunology. 2022; 2081001–1005.      [DOI] 

Chen H, et al . Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel. EMBO Mol Med. 2022; 14e14182.      [DOI] 

Chen H, Maul‐Pavicic A, Holzer M, et al . Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel. EMBO Mol Med. 2022; 14(1):      [DOI]      [Datei] 

Tauchert M, Bernemann I, Kühn-Steven A, Kopfnagel V, Kunze S, Illig T, Anton G. Digital knowledge management within the NAPKON study. Abstract. 11. Nationales Biobanken Symposium. 2022. Not available. 2022;

Vanshylla K, et al . Durability of omicron-neutralising serum activity after mRNA booster immunisation in older adults. The Lancet Infectious Diseases. 2022; 22445–446.      [DOI] 

Koerber N, Priller A, Yazici S, et al . Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescents. Nat Commun. 2022; 13(1):      [DOI] 

Akbil B, Meyer T, Stubbemann P, Thibeault C, Staudacher O, Niemeyer D, Jansen J, Mühlemann B, Doehn J, Tabeling C, Nusshag C, Hirzel C, Sanchez DS, Nieters A, Lother A, Duerschmied D, Schallner N, Lieberum JN, August D, Rieg S, Falcone V, Hengel H, Kölsch U, Unterwalder N, Hübner R, Jones TC, Suttorp N, Drosten C, Warnatz K, Spinetti T, Schefold JC, Dörner T, Sander LE, Corman VM, Merle U, Group P, Kurth F, Bernuth H, Meisel C, Goffinet C. Early and rapid identification of COVID-19 patients with neutralizing type I interferon auto-antibodies. J. Clin. Immunol.. 2022 Aug.; 42(6):1111—1129.      [DOI]  [Pubmed] 

Akbil B, et al . Early and Rapid Identification of COVID-19 Patients with Neutralizing Type I Interferon Auto-antibodies. Journal of Clinical Immunology. 2022;      [DOI] 

Pietzner M, Chua RL, Wheeler E, Jechow K, Radbruch H, Trump ea. ELF5 is a respiratory epithelial cell-specific risk gene for severe COVID-19. medRxiv. 2022;      [DOI] 

Hopff S, Tilch K, Kraus M, Lorenz-Depiereux L, Anton G, Appel K, Bahmer T, Bartschke A, Bellinghausen C, Bernemann I, others . Ethical and coordinative challenges in setting up a national cohort study exemplified by the German National Pandemic Cohort Network (NAPKON). Abstract ECCMID 2022. 2022;

Antoniou K, Vasarmidi E, Russell A, Andrejak C, Crestani B, Delcroix M, Dinh-Xuan A, Poletti V, Sverzellati N, Vitacca M, Witzenrath M, Tonia T, Spanevello A. European Respiratory Society statement on long COVID follow-up. Eur Respir J. 2022; 60(2):2102174.      [DOI] 

Krüger L, Klein J, Tobian F, others . Evaluation of accuracy, exclusivity, limit-of-detection and ease-of-use of LumiraDx™: An antigen-detecting point-of-care device for SARS-CoV-2. Infection. 2022; 50      [DOI]      [Datei] 

Hoffmann M, et al . Evidence for an ACE2-Independent Entry Pathway That Can Protect from Neutralization by an Antibody Used for COVID-19 Therapy. mBio. 2022;      [DOI] 

Hartung TJ, Neumann C, Bahmer T, Chaplinskaya-Sobol I, Endres M, Geritz J, Haeusler KG, Heuschmann PU, Hildesheim H, Hinz A, Hopff S, Horn A, Krawczak M, Krist L, Kudelka J, Lieb W, Maetzler C, Mehnert-Theuerkauf A, Montellano FA, Morbach C, Schmidt S, Schreiber S, Steigerwald F, Störk S, Maetzler W, Finke C. Fatigue and cognitive impairment after COVID-19: A prospective multicentre study. EClinicalMedicine. 2022 Nov.; 53(101651):101651.      [DOI]  [Pubmed] 

Ameratunga R, Woon S, Sheppard M, et al . First Identified Case of Fatal Fulminant Necrotizing Eosinophilic Myocarditis Following the Initial Dose of the Pfizer-BioNTech mRNA COVID-19 Vaccine (BNT162b2, Comirnaty): an Extremely Rare Idiosyncratic Hypersensitivity Reaction. J Clin Immunol. 2022;      [DOI] 

Von Stillfried S, Bülow R, Röhrig R, Boor P, Collaborators D. First report from the German COVID-19 autopsy registry. The Lancet Regional Health - Europe. 2022; 100330.      [DOI] 

Steinbeis F, Knape P, Mittermaier M, Helbig E, Tober-Lau P, Thibeault C, Lippert L, Xiang W, Müller-Plathe M, Steinbrecher S, others . Functional limitations 12 months after SARS-CoV-2 infection correlate with initial disease severity: An observational study of cardiopulmonary exercise capacity testing in COVID-19 convalescents. Respir Med. 2022; 202106968.      [DOI]