Publications in the NUM

Bräuninger H, Stoffers B, Fitzek ADE, Meißner K, Aleshcheva G, Schweizer M, Weimann J, Rotter B, Warnke S, Edler C, Braun F, Roedl K, Scherschel K, Escher F, Kluge S, Huber TB, Ondruschka B, Schultheiss H, Kirchhof P, Blankenberg S, Püschel K, Westermann D, Lindner D. Cardiac SARS-CoV-2 infection is associated with pro-inflammatory transcriptomic alterations within the heart. Cardiovascular Research. 2022 Jan.; 118(2):542—555.      [DOI] 

Lingscheid T, Lippert L, Hillus D, Kruis T, Thibeault C, Helbig E, Tober-Lau P, Pfäfflin F, Müller-Redetzky H, Witzenrath M, Zoller T, Uhrig A, Opitz B, Suttorp N, Kramer T, Sander L, Stegemann M, Kurth F. Characterization of antimicrobial use and co-infections among hospitalized patients with COVID-19: a prospective observational cohort study. Infection. 2022; 50(6):1441—1452.      [DOI] 

Walker A, Houwaart T, Finzer P, Ehlkes L, Tyshaieva A, Damagnez M, Strelow D, Duplessis A, Nicolai J, Wienemann T, Tamayo T, Kohns Vasconcelos M, Hülse L, Hoffmann K, Lübke N, Hauka S, Däumer M, Thielen A, Kolbe-Busch S, Göbels K, Zotz R, Pfeffer K, Timm J, Dilthey A. Characterization of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Clusters Based on Integrated Genomic Surveillance, Outbreak Analysis and Contact Tracing in an Urban Setting. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2022; 74(6):1039—1046.      [DOI] 

Dulovic A, et al . Comparative Magnitude and Persistence of Humoral SARS-CoV-2 Vaccination Responses in the Adult Population in Germany. Frontiers in Immunology. 2022; 13828053.      [DOI] 

Georg P, Astaburuaga-García R, Bonaguro L, Brumhard S, Michalick L, Lippert ea. Complement activation induces excessive T cell cytotoxicity in severe COVID-19. Cell. 2022; 185493—512.e425.

Brandner JM, Boor P, Borcherding L, Edler C, Gerber S, Heinemann A, Hilsenbeck J, Kasajima A, Lohner L, Märkl B, Pablik J, Schröder AS, Slotta-Huspenina J, Sommer L, Sperhake J, Stillfried S, Dintner S. Contamination of personal protective equipment during COVID-19 autopsies. Virchows Archiv. 2022 Mar.; 480(3):519—528.      [DOI]      [File] 

Brandner J, Boor P, Borcherding L, et al . Contamination of personal protective equipment during COVID-19 autopsies. Virchows Arch. 2022; 1-10.      [DOI] 

Mardiko A, Heinemann S, Bludau A, Kaba H, Leha A, von Maltzahn N, Mutters N, Leistner R, Mattner F, Scheithauer S. COVID-19 vaccination strategy for hospital staff in Germany: a cross-sectional study in March-April 2021. The Journal of hospital infection. 2022; 12687—92.      [DOI] 

Mardiko AA, Heinemann S, Bludau A, Kaba HEJ, Leha A, Maltzahn N, Mutters NT, Leistner R, Mattner F, Scheithauer S. COVID-19 vaccination strategy for hospital staff in Germany: a cross-sectional study in March–April 2021. Journal of Hospital Infection. 2022;      [DOI]      [File] 

Scheithauer S, Bludau A, Heinemann S, Anton M, Knolle P. COVID-19-Impfstrategien für Beschäftigte deutscher Kliniken: Ergebnisse einer Befragung von Leitungen der (Krankenhaus‑)Hygiene im Rahmen des B-FAST-Projektes [COVID-19 vaccination strategy for employees of German hospitals: results of a survey of infection control practitioners within the B-FAST project]. Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz. 2022;      [DOI]      [File] 

Scheithauer S, Bludau A, Heinemann S, Anton M, Knolle P. COVID-19-Impfstrategien für Beschäftigte deutscher Kliniken: Ergebnisse einer Befragung von Leitungen der (Krankenhaus‑)Hygiene im Rahmen des B-FAST-Projektes [COVID-19 vaccination strategy for employees of German hospitals: results of a survey of infection control practitioners within the B-FAST project]. Bundesgesundheitsbl. 2022 Dec.; 651299–1306.      [DOI]      [File] 

Scheithauer S, Bludau A, Heinemann S, Anton M, Knolle P. COVID-19-Impfstrategien für Beschäftigte deutscher Kliniken: Ergebnisse einer Befragung von Leitungen der (Krankenhaus\hbox-)Hygiene im Rahmen des B-FAST-Projektes. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 2022; 65(12):1299—1306.      [DOI] 

Radbruch L, Bausewein C. Covid-19: Was die Palliativmedizin leisten kann. Rheinisches Ärzteblatt. 2022; (6):

Tober-Lau P, et al . Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections. Emerging infectious diseases. 2022; 28      [DOI] 

Meyer-Arndt L, et al . Cutting Edge: Serum but Not Mucosal Antibody Responses Are Associated with Pre-Existing SARS-CoV-2 Spike Cross-Reactive CD4+ T Cells following BNT162b2 Vaccination in the Elderly. Journal of immunology. 2022; 2081001–1005.      [DOI] 

Chen H, et al . Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel. EMBO Mol Med. 2022; 14e14182.      [DOI] 

Chen H, Maul‐Pavicic A, Holzer M, et al . Detection and functional resolution of soluble immune complexes by an FcγR reporter cell panel. EMBO Mol Med. 2022; 14(1):      [DOI]      [File] 

Casagrande M, Fitzek A, Spitzer M, Püschel K, Glatzel M, Krasemann S, Aepfelbacher M, Nörz D, Lütgehetmann M, Pfefferle S, Schultheiss M. Detection of SARS-CoV-2 genomic and subgenomic RNA in retina and optic nerve of patients with COVID-19. The British Journal of Ophthalmology. 2022 Sep.; 106(9):1313—1317.      [DOI] 

H A, S E, F M, F S, H C, LH V, E V, A DO, D D, MFH B, BH A, PB S, T P, U H, A M, J N. Diagnostic Accuracy and Reliability of Noncontrast Computed Tomography Markers for Acute Hematoma Expansion among Radiologists.. Tomography (Ann Arbor, Mich.). 2022 Dec.;      [DOI] 

Tauchert M, Bernemann I, Kühn-Steven A, Kopfnagel V, Kunze S, Illig T, Anton G. Digital knowledge management within the NAPKON study. Abstract. 11. Nationales Biobanken Symposium. 2022. Not available. 2022;

C G, K G, M F, A B, A D, R F, IJ K, A M. Distance-based detection of out-of-distribution silent failures for Covid-19 lung lesion segmentation.. Medical image analysis. 2022 Nov.;      [DOI] 

Vanshylla K, et al . Durability of omicron-neutralising serum activity after mRNA booster immunisation in older adults. The Lancet Infectious Diseases. 2022; 22445–446.      [DOI] 

Heinrich F, Romich C, Zimmermann T, Kniep I, Fitzek A, Steurer S, Glatzel M, Nörz D, Günther T, Czech-Sioli M, Fischer N, Grundhoff A, Lütgehetmann M, Ondruschka B. Dying of VOC-202012/01 — multimodal investigations in a death case of the SARS-CoV-2 variant. International Journal of Legal Medicine. 2022 Jan.; 136(1):193—202.      [DOI]      [File] 

Koerber N, Priller A, Yazici S, et al . Dynamics of spike-and nucleocapsid specific immunity during long-term follow-up and vaccination of SARS-CoV-2 convalescents. Nat Commun. 2022; 13(1):      [DOI] 

Meyer T, Stubbemann P, Thibeault C, Staudacher O, Niemeyer D, Jansen J, Mühlemann B, Doehn J, Tabeling C, Nusshag C, Hirzel C, Sanchez DS, Nieters A, Lother A, Duerschmied D, Schallner N, Lieberum J, August D, Rieg S, Falcone V, Hengel H, Kölsch U, Unterwalder N, Hübner R, Jones TC, Suttorp N, Drosten C, Warnatz K, Spinetti T, Schefold JC, Dörner T, Sander LE, Corman V, Merle U, Group P, Kurth F, Bernuth H, Meisel C, Goffinet C. Early and rapid identification of COVID-19 patients with neutralizing type I interferon auto-antibodies. J. Clin. Immunol.. 2022 Aug.; 42(6):1111—1129.      [DOI]  [Pubmed] 

et al . Early and Rapid Identification of COVID-19 Patients with Neutralizing Type I Interferon Auto-antibodies. Journal of Clinical Immunology. 2022;      [DOI] 

Guarino M, Cossiga V, Esposito I, Furno A, Morisco F. Effectiveness of SARS-CoV-2 vaccination in liver transplanted patients: The debate is open!. Journal of Hepatology. 2022 Jan.; 76(1):237—239.      [DOI]      [File] 

Pietzner M, Chua RL, Wheeler E, Jechow K, Radbruch H, Trump ea. ELF5 is a respiratory epithelial cell-specific risk gene for severe COVID-19. medRxiv. 2022;      [DOI] 

Hopff S, Tilch K, Kraus M, Lorenz-Depiereux L, Anton G, Appel K, Bahmer T, Bartschke A, Bellinghausen C, Bernemann I, Stahl D. Ethical and coordinative challenges in setting up a national cohort study exemplified by the German National Pandemic Cohort Network (NAPKON). Abstract ECCMID 2022. 2022;

Antoniou K, Vasarmidi E, Russell A, Crestani B, Delcroix M, Dinh-Xuan A, Poletti V, Sverzellati N, Vitacca M, Witzenrath M, Tonia T, Spanevello A. European Respiratory Society statement on long COVID follow-up. Eur Respir J. 2022; 60(2):2102174.      [DOI] 

Krüger L, Klein J, Tobian F, Stahl D. Evaluation of accuracy, exclusivity, limit-of-detection and ease-of-use of LumiraDx™: An antigen-detecting point-of-care device for SARS-CoV-2. Infection. 2022; 50      [DOI]      [File] 

Hoffmann M, et al . Evidence for an ACE2-Independent Entry Pathway That Can Protect from Neutralization by an Antibody Used for COVID-19 Therapy. mBio. 2022;      [DOI] 

Menger J, Apostolidou S, Edler C, Kniep I, Kobbe R, Singer D, Sperhake J. Fatal outcome of SARS-CoV-2 infection (B1.1.7) in a 4-year-old child. International Journal of Legal Medicine. 2022 Jan.; 136(1):189—192.      [DOI]      [File] 

Hartung TJ, Neumann C, Bahmer T, Chaplinskaya-Sobol I, Endres M, Geritz J, Haeusler KG, Heuschmann PU, Hildesheim H, Hinz A, Hopff S, Horn A, Krawczak M, Krist L, Kudelka J, Lieb W, Maetzler C, Mehnert-Theuerkauf A, Montellano FA, Morbach C, Schmidt S, Schreiber S, Steigerwald F, Störk S, Maetzler W, Finke C. Fatigue and cognitive impairment after COVID-19: A prospective multicentre study. EClinicalMedicine. 2022 Nov.; 53(101651):101651.      [DOI]  [Pubmed] 

Woon S, Sheppard M, et al . First Identified Case of Fatal Fulminant Necrotizing Eosinophilic Myocarditis Following the Initial Dose of the Pfizer-BioNTech mRNA COVID-19 Vaccine (BNT162b2, Comirnaty): an Extremely Rare Idiosyncratic Hypersensitivity Reaction. J Clin Immunol. 2022;      [DOI] 

Von Stillfried S, Bülow R, Röhrig R, Boor P, Collaborators D. First report from the German COVID-19 autopsy registry. The Lancet Regional Health - Europe. 2022; 100330.      [DOI] 

Stillfried S, Bülow RD, Röhrig R, Boor P, COVID-19 Autopsies (DeRegCOVID) DC. First report from the German COVID-19 autopsy registry. The Lancet Regional Health. Europe. 2022 Apr.; 15100330.      [DOI] 

Steinbeis F, Knape P, Mittermaier M, Helbig E, Tober-Lau P, Thibeault C, Lippert L, Xiang W, Müller-Plathe M, Steinbrecher S, Stahl D. Functional limitations 12 months after SARS-CoV-2 infection correlate with initial disease severity: An observational study of cardiopulmonary exercise capacity testing in COVID-19 convalescents. Respir Med. 2022; 202106968.      [DOI] 

Rosenau L, Majeed RW, Ingenerf J, Kiel A, Kroll B, Köhler T, Prokosch H, Gruendner J. Generation of a Fast Healthcare Interoperability Resources (FHIR)-based Ontology for federated Feasibility Queries in the context of COVID-19: An automated approach. JMIR Med Inform. 2022 Apr.; 10(4):e35789.      [DOI] 

Kühnapfel A, Horn K, Klotz U, Kiehntopf M, Rosolowski M, Loeffler M, Suttorp N, Witzenrath M, Scholz M. Genetic Regulation of Cytokine Response in Patients with Acute Community-Acquired Pneumonia. Genes (Basel). 2022; 13(1):111.      [DOI] 

Hirschbühl K, Schaller T, Märkl B, Claus R, Sipos E, Rentschler L, Maccagno A, Grosser B, Kling E, Neidig M, Kröncke T, Spring O, Braun G, Bösmüller H, Seidl M, Esposito I, Pablik J, Hilsenbeck J, Boor P, Beer M, Dintner S, Wylezich C. High viral loads: what drives fatal cases of COVID-19 in vaccinees? – an autopsy study. Modern Pathology. 2022 Aug.; 35(8):1013—1021.      [DOI]      [File] 

Dannebaum R, Suwalski P, Asgharian H, Du ZG, Lin H, Weiner J, Holtgrewe M, Thibeault C, Müller M, Wang X, Stahl D. Highly multiplexed immune repertoire sequencing links multiple lymphocyte classes with severity of response to COVID-19. EClinicalMedicine. 2022; 48101438.      [DOI] 

Hönzke K, Obermayer B, Mache C, Fathykova D, Kessler M, Dökel S, Wyler E, Baumgardt M, Löwa A, Hoffmann K, Stahl D. Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages. Eur Respir J. 2022; 60(6):2102725.      [DOI] 

Hönzke K, Obermayer B, Mache C, Fathykova D, Kessler M, Dökel ea. Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages. Eur Respir J. 2022; 60(6):2102725.      [DOI] 

Wolff AW, Haller B, Demleitner AF, Westenberg E, Lingor P. Impact of the COVID-19 pandemic on patients with Parkinson's Disease from the perspective of treating physicians-A nationwide cross-sectional study. Brain Sci.. 2022 Mar.; 12(3):353.

Sedlmayr B, Sedlmayr M, Schüttler C, et al . Improving collaborative COVID-19 research of University Hospitals in Germany: Formative usability evaluation of the CODEX-Feasibility Portal. Appl Clin Inform. 2022; 13400—409.      [DOI] 

Wratil PR, Schmacke NA, Osterman A, et al . In-depth profiling of COVID-19 risk factors and preventive measures in healthcare workers. Infection. 2022; 50      [DOI] 

Dragano N, Reuter M, Peters A, Engels M, Schmidt B, Greiser K, Bohn B, Riedel-Heller S, Karch A, Mikolajczyk R, Krause G, Lang O, Panreck L, Rietschel M, Brenner H, Fischer B, Franzke C, Gastell S, Holleczek B, Jöckel K, Kaaks R, Keil T, Kluttig A, Kuß O, Legath N, Leitzmann M, Lieb W, Meinke-Franze C, Michels K, Obi N, Pischon T, Feinkohl I, Rospleszcz S, Schikowski T, Schulze M, Stang A, Völzke H, Willlich S, Wirkner K, Zeeb H, Berger K. Increase in mental disorders during the COVID-19 pandemic - the role of occupational and financial strains. An analysis of the German National Cohort (NAKO) Study. Deutsches Ärzteblatt International. 2022; 119179–187.      [DOI] 

Bludau A, Heinemann S, Mardiko A, Kaba H, Leha A, von Maltzahn N, Mutters N, Leistner R, Mattner F, Scheithauer S. Infection control strategies for patients and accompanying persons during the COVID-19 pandemic in German hospitals: a cross-sectional study in March-April 2021. The Journal of hospital infection. 2022; 12528—36.      [DOI] 

Bludau A, Heinemann S, Mardiko AA, Kaba HEJ, Leha A, Maltzahn N, Mutters NT, Leistner R, Mattner F, Scheithauer S. Infection control strategies for patients and accompanying persons during the COVID-19 pandemic in German hospitals: a cross-sectional study in March–April 2021. Journal of Hospital Infection. 2022;      [DOI]      [File]