Methodological consulting
NUM-MB supports the application and utilisation of data and biosamples collected in NUM studies and offers methodological, regulatory and logistical support.
Data & Biosamples
NUKLEUS manages a wide range of data collected as part of multicentre clinical and epidemiological studies or obtained from external data providers: clinical, biosample, analysis, care and metadata, currently from the three NAPKON cohorts, with further studies underway. As of 2025, over 50,000 reusable study visits, over 250,000 biosamples and over 275,000 DICOM documents (image and biosignal data) are available. In NUM 3.0, NUKLEUS will be expanded to include the linking and management of external healthcare-related data, in particular health insurance and cancer registry data.
Application procedure
Applications are submitted via the NUKLEUS coordination unit Dynamic Use & Access.
Data & biosamples
A baseline cohort is continuously being established, which includes data and biosamples from adult, hospitalised patients on respiratory, bloodstream, gastrointestinal and CNS infections as well as emerging infectious diseases. The data collected includes Medical history, diagnoses, laboratory, medication, vital signs, EQ-5D as well as blood and module-specific biosamples. A linkage to data from routine care and other care data (health insurance companies, cancer register) is being systematically established.
Application procedure
The data and biosamples obtained as part of the basic cohort can be used for individual research projects after a positive review by the NUKLEUS Use & Access Committee, also in conjunction with routine data from the Data Integration Centres (see also entry "NUM-DIZ").
Contact:
UAC: uac@nukleus.netzwerk-universitaetsmedizin.de
SNID: snid@sn.netzwerk-universitaetsmedizin.de
The "Sample Locator" enables a comprehensive search for human biosamples and associated data in GBN biobanks. Researchers can start a feasibility enquiry and, after authentication, see how many samples from how many donors are available at which locations. As of 2025, samples from over 120,000 donors can be found in the Sample Locator.
After a search query in the Sample Locator or in the directory, contact is made via a connected chat tool.
Contact: germanbiobanknetwork@charite.de
Data
RACOON offers quality-assured, pseudonymised image data (CT, MRI, X-ray, etc.) with standardised findings according to FAIR principles.
Application procedure
After review and approval by the responsible committees, the data can be used for research projects, multi-centre studies and AI analyses via the NUM infrastructure.
Contact: office@racoon.network
Data & biosamples
The NUM-DIZ provide data from university patient care. Core data sets based on the international standard 'FHIR' (Fast Healthcare Interoperability Resources) and terminologies serve as the basis for cross-site research. As of 2025, 21 million patient, 2 billion laboratory, 250 million diagnostic, 100 million procedure, 250 million medication, 1.6 million biospecimen and 700k consent resources are available. Researchers can use the Research Data Portal for Health (FDPG) to get an overview of the available data, carry out targeted feasibility queries and apply for data.
Application procedure
If interested, an application is submitted, which is decided on by the local Use and Access Committees (UAC). A nationally harmonised usage agreement is then concluded. Researchers can be provided with pseudonymised data (usually under the legal basis of broad consent) or they can develop scripts that are evaluated locally and receive aggregated results. Tools for federated analyses and machine learning are also being developed.
Contact: mii-num-diz-koordination@fau.de
Data & biosamples
Pseudonymised routine data from 8.5 million cases from the electronic emergency admission documentation has been available since 2019, including patient characteristics, diagnoses, triage and whereabouts. For some of the cases that were admitted as inpatients from the Emergency Departments, inpatient treatment data is also available in accordance with Section 21 KHEntgG. The number of available data records increases by around 1.5 million cases every year. This is based on the DIVI emergency documentation dataset. In future, the infrastructure is to be expanded to include data from intensive care medicine (NUM project RAPID).
Application procedure
The AKTIN data can be applied for scientific projects, quality assurance and care analyses. An application for data analysis is submitted to the AKTIN Data Use and Access Committee.
Contact: office@aktin.org
Data & biosamples
NATON supports researchers with a central data platform that operates the National Autopsy Registry (NAREG). It provides structured, annotated and curated autopsy data and coordinates the exchange between autopsy centres and researchers. The data collected by the individual post-mortem centres can be made available for further studies. NATON provides 2,780 autopsy datasets with information on more than 67,000 post-mortem tissue samples.
Application procedure
If you are interested, please contact the NATON Office directly.
Contact: info@naton.network