Publications in the NUM

Borsche M, Balck A, et al . Spreading of SARS-CoV-2 Among Adult Asylum Seekers in Refugee Shelters in Germany. Lancet. 2021;      [DOI] 

Geraedts M, Eberlein-Gonska M, Hecker R, Schneider K, Schroeder-Printzen I, Zeuner M. Stationäre Versorgung: Empfehlungen für ein künftiges Pandemiemanagement. Dtsch Arztebl International. 2021; 118(19—20):A-991.

Torres Reyes CR, Steinmann E, Timmesfeld N, et al . Students in Dormitories were not major drivers of the pandemic during winter term 2020/2021: A cohort study with RT-PCR and antibody surveillance in a German university city. COVID. 2021; 1(1):      [DOI] 

Warnat-Herresthal S, et al . Swarm Learning for decentralized and confidential clinical machine learning. Nature. 2021;      [DOI] 

Hempel T, et al . Synergistic inhibition of SARS-CoV-2 cell entry by otamixaban and covalent protease inhibitors: pre-clinical assessment of pharmacological and molecular properties. Chemical Science. 2021; 1212600–12609.      [DOI] 

Wagner C, Griesel M, Mikolajewska A, Mueller A, Nothacker M, Kley K, Metzendorf M, Fischer A, Kopp M, Stegemann M, Skoetz N, Fichtner F. Systemic corticosteroids for the treatment of COVID-19. Cochrane Database of Systematic Reviews. 2021; 2021CD014963.      [DOI] 

O'Hare M, Amarnani D, Whitmore HAB, An M, Marino C, Ramos L, Delgado-Tirado S, Hu X, Chmielewska N, Chandrahas A, Fitzek A, Heinrich F, Steurer S, Ondruschka B, Glatzel M, Krasemann S, Sepulveda-Falla D, Lagares D, Pedron J, Bushweller JH, Liu P, Arboleda-Velasquez JF, Kim LA. Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators. The American Journal of Pathology. 2021 Jul.; 191(7):1193—1208.      [DOI]      [File] 

O'Hare M, Whitmore HAB, Marino C, Ramos L, Delgado-Tirado S, Hu X, Chmielewska N, Chandrahas A, Stahl D. Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators. Am J Pathol. 2021; 191(7):1193-1208.      [DOI] 

Baldinger M, Heinrich A, Martens E, Dommasch M, Muller A, Siegmann A, Schmidt G, Laerhoven KV. TELECOVID: Remote Vital Signs Monitoring of COVID-19 Risk Patients in Home Isolation With an In-Ear Wearable. IEEE Pervasive Computing. 2021; 20(2):58—62.      [DOI] 

Nouailles G, Wyler E, Pennitz P, Postmus D, Vladimirova D, Kazmierski ea. Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19. Nat Commun. 2021; 124869.      [DOI] 

Nouailles G, Wyler E, Pennitz P, Postmus D, Vladimirova D, Kazmierski J, Pott F, Dietert K, Muelleder M, Farztdinov V, Stahl D. Temporal omics analysis in Syrian hamsters unravel cellular effector responses to moderate COVID-19. Nat Commun. 2021; 12(1):4869.      [DOI] 

Krüger L, Gaeddert M, Tobian F, Stahl D. The Abbott PanBio WHO emergency use listed, rapid, antigen-detecting point-of-care diagnostic test for SARS-CoV-2—Evaluation of the accuracy and ease-of-use. PLOS ONE. 2021; 16(5):      [DOI]      [File] 

Witzenrath M, Kuebler W. The CypA-netics of Ventilator-induced Lung Injury. Am J Respir Crit Care Med. 2021; 204(4):385—387.      [DOI] 

Ramirez Alvarez C, Kee C, Sharma AK, Thomas L, Schmidt FI, Stanifer ea. The endogenous cellular protease inhibitor SPINT2 controls SARS-CoV-2 viral infection and is associated with disease severity. PLOS Pathogens. 2021; 17(5):e1009687.      [DOI] 

Schröder AS, Edler C, Ondruschka B, Püschel K, Schädler J, Heinemann A, Heinrich F, Lütgehetmann M, Pfefferle S, Aepfelbacher M, Fitzek A, Sperhake J. The handling of SARS-CoV-2 associated deaths - infectivity of the body. Forensic Science, Medicine and Pathology. 2021 Sep.; 17(3):411—418.      [DOI]      [File] 

Hornung F, Rogal J, Loskill P, Löffler B, Deinhardt-Emmer S. The Inflammatory Profile of Obesity and the Role on Pulmonary Bacterial and Viral Infections. Int J Mol Sci. 2021; 22

Clemens V, Beschoner P, Jarczok M, Weimer K, Kempf M, Morawa E, Geiser F, Steudte-Schmiedgen S, Gündel H, Fegert J, Jerg-Bretzke L. The mediating role of COVID-19-related burden in the association between adverse childhood experiences and emotional exhaustion: Results of the egePan–VOICE study. European Journal of Psychotraumatology. 2021; 12(1):1976441.      [DOI] 

Hoffmann M, et al . The Omicron variant is highly resistant against antibody-mediated neutralization: Implications for control of the COVID-19 pandemic. Cell. 2021;      [DOI] 

Wachinger J, Olaru ID, Horner S, et al . The potential of SARS-CoV-2 antigen-detection tests in the screening of asymptomatic persons. Clin Microbiol Infect. 2021; 27(11):      [DOI]      [File] 

Bösmüller H, Matter M, Fend F, Tzankov A. The pulmonary pathology of COVID-19. Virchows Archiv. 2021 Jan.; 478(1):137—150.      [DOI]      [File] 

Panchyrz I, Pohl S, Hoffmann J, Gatermann C, Walther F, Harst L, Held H, Kleber C, Schmitt J. The role of university hospitals in regional health care management for coping with the COVID-19 pandemic. Zeitschrift Für Evidenz, Fortbildung Und Qualität Im Gesundheitswesen. 2021; 16768—77.      [DOI] 

Wenzel J, Lampe J, Müller-Fielitz H, et al . The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells. Nat Neurosci. 2021; 24(11):1522-1533.      [DOI] 

Wenzel J, Lampe J, Müller-Fielitz H, Schuster R, Zille M, Müller K, Krohn M, Körbelin J, Zhang L, Özorhan Ü, Neve V, Wagner JUG, Bojkova D, Shumliakivska M, Jiang Y, Fähnrich A, Ott F, Sencio V, Robil C, Pfefferle S, Sauve F, Coêlho CFF, Franz J, Spiecker F, Lembrich B, Binder S, Feller N, König P, Busch H, Collin L, Villaseñor R, Jöhren O, Altmeppen HC, Pasparakis M, Dimmeler S, Cinatl J, Püschel K, Zelic M, Ofengeim D, Stadelmann C, Trottein F, Nogueiras R, Hilgenfeld R, Glatzel M, Prevot V, Schwaninger M. The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells. Nature Neuroscience. 2021 Nov.; 24(11):1522—1533.      [DOI]      [File] 

Kitazawa K, Deinhardt-Emmer S, Inomata T, Deshpande S, Sotozono C. The Transmission of SARS-CoV-2 Infection on the Ocular Surface and Prevention Strategies. Cells. 2021; 10

Muzoora MR, et al . Towards FAIR Patient Reported Outcome: Application of the Interoperability Principle for Mobile Pandemic Apps. Stud Health Technol Inform. 2021; 28785—86.      [DOI] 

Wulff A, Biermann P, Landesberger T, Baumgartl T, Schmidt C, Alhaji AY, Schick K, Waldstein P, Zhu Y, Group HICS, Krefting D, Scheithauer S, Marschollek M. Tracing COVID-19 Infection Chains Within Healthcare Institutions – Another Brick in the Wall Against SARS-CoV-2. Studies in Health Technology and Informatics. 2021;      [DOI]      [File] 

Wulff A, Biermann P, von Landesberger T, Baumgartl T, Schmidt C, Alhaji A, Schick K, Waldstein P, Zhu Y, HiGHmed Infection Control Study Group , Krefting D, Scheithauer S, Marschollek M. Tracing COVID-19 infection chains within healthcare institutions: Another brick in the wall against SARS-CoV-2. Studies in Health Technology and Informatics. 2021; 290: MEDINFO 2021: One World, One Health – Global699 - 703.      [DOI]      [File] 

Wyler E, Mosbauer K, Franke V, Diag A, Gottula LT, Arsie ea. Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy. iScience. 2021; 24102151.      [DOI] 

Verhoff M, Püschel K, Ondruschka B. Über die Ansteckungsgefahr beim Umgang mit SARS-CoV-2-positiven Leichen. Bestattungskultur. 2021; (5):24—28.     [File] 

Backhaus I, Hermsen D, Timm J, Boege F, Lübke N, Göbels K, Lieth D, Dragano N. Under-ascertainment of COVID-19 cases among first responders: a seroepidemiological study. Occupational Medicine. 2021; kqab164.      [DOI] 

Schuster S, Lisack J, Subota I, Zimmermann H, Reuter C, Mueller ea. Unexpected plasticity in the life cycle of Trypanosoma brucei. Elife. 2021; 10      [DOI] 

Klinger C, Burns J, Movsisyan A, Biallas R, Norris SL, Rabe JE, Stratil JM, Voss S, Wabnitz K, Rehfuess E, Verboom B. Unintended health and societal consequences of international travel measures during the COVID-19 pandemic: A scoping review. J Travel Med. 2021;      [DOI] 

Witkowski M, Tizian C, Ferreira-Gomes M, Niemeyer D, Jones TC, Heinrich F, Frischbutter S, Angermair S, Hohnstein T, Mattiola I, Nawrath P, McEwen S, Zocche S, Viviano E, Heinz GA, Maurer M, Kölsch U, Chua RL, Aschman T, Meisel C, Radke J, Sawitzki B, Roehmel J, Allers K, Moos V, Schneider T, Hanitsch L, Mall MA, Conrad C, Radbruch H, Duerr CU, Trapani JA, Marcenaro E, Kallinich T, Corman VM, Kurth F, Sander LE, Drosten C, Treskatsch S, Durek P, Kruglov A, Radbruch A, Mashreghi M, Diefenbach A. Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells. Nature. 2021 Dec.; 600(7888):295—301.      [DOI]      [File] 

Witkowski M, Tizian C, Ferreira-Gomes M, Niemeyer D, Jones TC, Heinrich ea. Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells. Nature. 2021;      [DOI] 

Witkowski M, Tizian C, Ferreira-Gomes M, et al . Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells. Nature. 2021; 600(7888):295-301.      [DOI] 

Witkowski M, et al . Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells. Nature. 2021;      [DOI] 

Berezowska S, Boor P, Jonigk D, Tischler V. Update on thoracic pathology 2021-report of the working group thoracic pathology of the German Society of Pathology. Pathologe. 2021; 1-4.      [DOI] 

Berezowska S, Boor P, Jonigk D, Tischler V. Update Thoraxpathologie 2021 – Bericht der Arbeitsgemeinschaft. Der Pathologe. 2021 Dec.; 42(2):199—202.      [DOI]      [File] 

Tampe D, Hakroush S, Bösherz M, Franz J, Hofmann-Winkler H, Pöhlmann S, Kluge S, Moerer O, Stadelmann C, Ströbel P, Winkler MS, Tampe B. Urinary Levels of SARS-CoV-2 Nucleocapsid Protein Associate With Risk of AKI and COVID-19 Severity: A Single-Center Observational Study. Frontiers in Medicine. 2021 May; 8644715.      [DOI]      [File] 

Dittmayer C, Meinhardt J, Radbruch H, Radke J, Heppner BI, Heppner FL, Stenzel W, Holland G, Laue M. Using EM data to understand COVID-19 pathophysiology – Authors' reply. The Lancet. 2021 Jan.; 397(10270):197—198.      [DOI]      [File] 

Boender TS, Cai W, Schranz M, Stahl D. Using routine emergency department data for syndromic surveillance of acute respiratory illness before and during the COVID-19 pandemic in Germany, week 10-2017 and 10-2021. medRxiv. 2021 Aug.;      [DOI] 

Gross O, Moerer O, Rauen T, et al . Validation of a Prospective Urinalysis-Based Prediction Model for ICU Resources and Outcome of COVID-19 Disease: A Multicenter Cohort Study. J Clin Med. 2021; 10(14):      [DOI] 

Nicolai L, Leunig A, Brambs S, Kaiser R, Joppich M, Hoffknecht M, Gold C, Engel A, Polewka V, Muenchhoff M, Stahl D. Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID-19 from influenza pneumonia. J Thromb Haemost. 2021; 19(2):574-581.      [DOI] 

Nicolai L, Leunig A, Brambs S, Kaiser R, Joppich M, Hoffknecht M, Gold C, Engel A, Polewka V, Muenchhoff M, Hellmuth JC, Ruhle A, Ledderose S, Weinberger T, Schulz H, Scherer C, Rudelius M, Zoller M, Keppler OT, Zwißler B, Bergwelt‐Baildon M, Kääb S, Zimmer R, Bülow RD, Stillfried S, Boor P, Massberg S, Pekayvaz K, Stark K. Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID‐19 from influenza pneumonia. Journal of Thrombosis and Haemostasis. 2021 Feb.; 19(2):574—581.      [DOI]      [File] 

Roedl K, Heidenreich S, Pfefferle S, Jarczak D, Urbanowicz TT, Nörz D, Aepfelbacher M, Kröger N, Kluge S, Lütgehetmann M, Christopeit M, Wichmann D. Viral Dynamics of SARS-CoV-2 in Critically Ill Allogeneic Hematopoietic Stem Cell Transplant Recipients and Immunocompetent Patients with COVID-19. American Journal of Respiratory and Critical Care Medicine. 2021 Jan.; 203(2):242—245.      [DOI]      [File] 

Roedl K, Heidenreich S, Pfefferle S, Jarczak D, Urbanowicz TT, Nörz D, Kröger N, Kluge S, Lütgehetmann M, Christopeit M, Wichmann D. Viral Dynamics of SARS-CoV-2 in Critically Ill Allogeneic Hematopoietic Stem Cell Transplant Recipients and Immunocompetent Patients with COVID-19. Am J Respir Crit Care Med. 2021; 203(2):242-245.

Stroehlein JK, Wallqvist J, Iannizzi C, Mikolajewska A, Metzendorf M, Benstoem C, Meybohm P, Becker M, Skoetz N, Stegemann M, Piechotta V. Vitamin D supplementation for the treatment of COVID-19: a living systematic review. Cochrane Database of Systematic Reviews. 2021; 2021CD015043.      [DOI] 

Weigang S, Fuchs J, Zimmer G, et al . Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants. Nat Commun. 2021; 12(1):      [DOI]      [File] 

Eggers D. Best practice models for nursing care in the COVID-19-pandemic: a web-based survey. Joint Scientific Summer Conference DGP/EANS. Lessons learned from the pandemic in different nursing settings. 02.07.2021. Vortrag.. In: 2021.

Metzendorf M, Hildebrandt J, Jakob T, Featherstone RM. Das Cochrane COVID-19 Studienregister – eine studienbasierte, strukturierte Datenbank zur effizienten Identifizierung wissenschaftlicher Evidenz. In: Vortrag. 22. Jahrestagung des Deutschen Netzwerks Evidenzbasierte Medizin. 2021.