Publications in the NUM

Here you will find a list of publications that were written in connection with the Network of University Medicine in the first and second funding phases.

Ankerhold J, Giese S, Kolb P, et al . Circulating multimeric immune complexes drive immunopathology in COVID-19. Immunology. 2021;      [DOI] 
Hofman P, Ilié M, Chamorey E, Brest P, Schiappa R, Nakache V, Antoine M, Barberis M, Begueret H, Bibeau F, Bonnetaud C, Boström P, Brousset P, Bubendorf L, Carvalho L, Cathomas G, Cazes A, Chalabreysse L, Chenard M-, Copin M-, Côté J-, Damotte D, Leval L, Delongova P, Montpreville V, Muret A, Dema A, Dietmaier W, Evert M, Fabre A, Forest F, Foulet A, Garcia S, Garcia-Martos M, Gibault L, Gorkiewicz G, Jonigk D, Gosney J, Hofman A, Kern I, Kerr K, Kossai M, Kriegsmann M, Lassalle S, Long-Mira E, Lupo A, Mamilos A, Matěj R, Meilleroux J, Ortiz-Villalón C, Panico L, Panizo A, Papotti M, Pauwels P, Pelosi G, Penault-Llorca F, Pop O, Poté N, Cajal SRY, Sabourin J-, Salmon I, Sajin M, Savic-Prince S, Schildhaus H-, Schirmacher P, Serre I, Shaw E, Sizaret D, Stenzinger A, Stojsic J, Thunnissen E, Timens W, Troncone G, Werlein C, Wolff H, Berthet J-, Benzaquen J, Marquette C-, Hofman V, Calabrese F. Clinical and molecular practice of European thoracic pathology laboratories during the COVID-19 pandemic. The past and the near future. ESMO Open. 2021 Feb.; 6(1):100024.      [DOI]      [File] 
Thibeault C, Mühlemann B, Helbig E, Mittermaier M, Lingscheid T, Tober-Lau P, Meyer-Arndt L, Meiners L, Stubbemann P, Haenel S, Stahl D. Clinical and virological characteristics of hospitalised COVID-19 patients in a German tertiary care centre during the first wave of the SARS-CoV-2 pandemic: a prospective observational study. Infection. 2021; 49(4):703—714.      [DOI] 
Thibeault C, et al . Clinical and virological characteristics of hospitalised COVID-19 patients in a German tertiary care centre during the first wave of the SARS-CoV-2 pandemic: a prospective observational study. Infection. 2021;      [DOI] 
Nörz D, Hoffmann A, Aepfelbacher M, Pfefferle S, Lütgehetmann M. Clinical evaluation of a fully automated, laboratory-developed multiplex RT-PCR assay integrating dual-target SARS-CoV-2 and influenza A/B detection on a high-throughput platform. Journal of Medical Microbiology. 2021 Feb.; 70(2):001295.      [DOI]      [File] 
Zhao Y, Kilian C, Turner J, Bosurgi L, Roedl K, Bartsch P, Gnirck A, Cortesi F, Schultheiß C, Hellmig M, Enk LUB, Hausmann F, Borchers A, Wong MN, Paust H, Siracusa F, Scheibel N, Herrmann M, Rosati E, Bacher P, Kylies D, Jarczak D, Lütgehetmann M, Pfefferle S, Steurer S, Zur-Wiesch JS, Puelles VG, Sperhake J, Addo MM, Lohse AW, Binder M, Huber S, Huber TB, Kluge S, Bonn S, Panzer U, Gagliani N, Krebs CF. Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients. Science Immunology. 2021 Feb.; 6(56):eabf6692.      [DOI] 
Mikolajewska A, Fischer A, Piechotta V, Mueller A, Metzendorf M, Becker M, Dorando E, Pacheco R, Martimbianco ALC, Riera R, Skoetz N, Stegemann M. Colchicine for the treatment of COVID‐19. Cochrane Database of Systematic Reviews. 2021; 2021CD015045.      [DOI] 
Ochs M, Timm S, Elezkurtaj S, Horst D, Meinhardt J, Heppner ea. Collapse induration of alveoli is an ultrastructural finding in a COVID-19 patient. Eur Respir J. 2021; 57      [DOI] 
Herbst K, Meurer M, Kirrmaier D, Stahl D. Colorimetric RT-LAMP and LAMP-sequencing for Detecting SARS-CoV-2 RNA in Clinical Samples. BIO-Protocols. 2021; 11(6):      [DOI]      [File] 
Brunotte L, Zheng S, Mecate-Zambrano A, Tang J, Ludwig S, Rescher ea. Combination Therapy with Fluoxetine and the Nucleoside Analog GS-441524 Exerts Synergistic Antiviral Effects against Different SARS-CoV-2 Variants In Vitro. Pharmaceutics. 2021; 13
Müller A, Engler F, Schütze D, Nohl-Deryk P, Güthlin C. Communication experience by secure instant messaging during the Covid-19 pandemic for general practitioners and public health workers – a qualitative analysis. Doc21dkvf051. 2021;      [DOI] 
Osterman A, Iglhaut M, Lehner A, et al . Comparison of four commercial, automated antigen tests to detect SARS-CoV-2 variants of concern. Med Microbiol Immunol. 2021; 210      [DOI] 
Osterman A, Iglhaut M, Lehner A, Spaeth P, Stern M, Autenrieth H, Muenchhoff M, Graf A, Krebs S, Blum H, Baiker A, Grzimek-Koschewa N, Protzer U, Kaderali L, Baldauf H, Keppler OT. Comparison of four commercial, automated antigen tests to detect SARS-CoV-2 variants of concern. Medical Microbiology and Immunology. 2021;      [DOI]      [File] 
Osterman A, Iglhaut M, Lehner A, Späth P, Stern M, Autenrieth H, Muenchhoff M, Graf A, Krebs S, Blum H, Baiker A, Grzimek-Koschewa N, Protzer U, Kaderali L, Baldauf H, Keppler O. Comparison of four commercial, automated antigen tests to detect SARS-CoV-2 variants of concern. Medical microbiology and immunology. 2021; 210(5-6):263—275.      [DOI] 
Georg P, et al . Complement activation induces excessive T cell cytotoxicity in severe COVID-19. Cell. 2021;      [DOI] 
Georg P, Astaburuaga-García R, Bonaguro L, et al . Complement activation induces excessive T cell cytotoxicity in severe COVID-19. Cell. 2021;      [DOI] 
Föh B, Borsche M, Balck A, et al . Complications of nasal and pharyngeal swabs – a relevant challenge of the COVID-19 pandemic?. Eur Respir J. 2021;      [DOI] 
Piechotta V, Iannizzi C, Chai KL, Valk SJ, Kimber C, Dorando E, Monsef I, Wood EM, Lamikanra AA, Roberts DJ, McQuilten Z, So-Osman C, Estcourt LJ, Skoetz N. Convalescent plasma or hyperimmune immunoglobulin for people with COVID‐19: a living systematic review. Cochrane Database of Systematic Reviews. 2021; 2021CD013600.      [DOI] 
Beierle F, et al . Corona Health—A Study- and Sensor-Based Mobile App Platform Exploring Aspects of the COVID-19 Pandemic. Int J Environ Res Public Health. 2021; 187395.      [DOI] 
Steudte-Schmiedgen S, Stieler L, Erim Y, Morawa E, Geiser F, Beschoner P, Jerg-Bretzke L, Hiebel N, Weidner K. Correlates and Predictors of PTSD Symptoms Among Healthcare Workers During the COVID-19 Pandemic: Results of the egePan-VOICE Study. Frontiers in Psychiatry. 2021; 12      [DOI]      [File] 
Ebigbo A, Römmele C, Bartenschlager C, et al . Cost-effectiveness analysis of SARS-CoV-2 infection prevention strategies including pre-endoscopic virus testing and use of high risk personal protective equipment. Endoscopy. 2021; 53(2):      [DOI] 
Baumann M. COVID-19 and mental health in children and adolescents: a diagnostic panel to map psycho-social consequences in the pandemic context. Discov Ment Health. 2021; 1(1):2.      [DOI] 
Ritschel N, Radbruch H, Herden C, Schneider N, Dittmayer C, Franz ea. COVID-19 and the central and peripheral nervous system. Pathologe. 2021; 42172—182.      [DOI] 
Ul Ain Q, Hocke A, Hedtrich S. COVID-19 highlights the model dilemma in biomedical research. Nat Rev Mater. 2021; 1—3.
Roth W, Boor P. COVID-19 im Spiegel der Pathologie. Der Pathologe. 2021 Mar.; 42(2):147—148.      [DOI]      [File] 
Roth W, Boor P. COVID-19 im Spiegel der Pathologie [COVID-19 in the mirror of pathology]. Pathologe. 2021; 42(2):147-148.
Gaitzsch E, et al . COVID-19 in Patients Receiving CD20-depleting Immunochemotherapy for B-cell Lymphoma. HemaSphere. 2021; 5e603.      [DOI] 
Gaitzsch E, Passerini V, Khatamzas E, et al . COVID-19 in Patients Receiving CD20-depleting Immunochemotherapy for B-cell Lymphoma. Hemasphere. 2021; 5(7):      [DOI] 
Smadja DM, Mentzer SJ, Fontenay M, Laffan MA, Ackermann M, Helms J, Jonigk D, Chocron R, Pier GB, Gendron N, Pons S, Diehl J, Margadant C, Guerin C, Huijbers EJM, Philippe A, Chapuis N, Nowak-Sliwinska P, Karagiannidis C, Sanchez O, Kümpers P, Skurnik D, Randi AM, Griffioen AW. COVID-19 is a systemic vascular hemopathy: insight for mechanistic and clinical aspects. Angiogenesis. 2021 Nov.; 24(4):755—788.      [DOI]      [File] 
Kniep I, Heinemann A, Edler C, Sperhake JP, Püschel K, Ondruschka B, Schröder AS. COVID-19 lungs in post-mortem computed tomography. Rechtsmedizin. 2021 Apr.; 31(2):145—147.      [DOI]      [File] 
Heinemann S, Bludau A, Kaba H, et al . COVID-19 surveillance and testing strategies für patiens in German hospitals – results from a cross-sectional study. DGHM. 2021;     [File] 
Tanacli R, Doeblin P, Götze C, Zieschang V, Faragli A, Stehning C, Korosoglou G, Erley J, Weiss J, Berger A, Stahl D. COVID-19 vs. Classical Myocarditis Associated Myocardial Injury Evaluated by Cardiac Magnetic Resonance and Endomyocardial Biopsy. Front Cardiovasc Med. 2021; 8737257.      [DOI] 
Amann K, Boor P, Wiech T, Singh J, Vonbrunn E, Knöll A, Hermann M, Büttner-Herold M, Daniel C, Hartmann A. COVID-19-Auswirkungen auf die Niere. Der Pathologe. 2021 Mar.; 42(2):183—187.      [DOI]      [File] 
Boor P, Wiech T, Singh J, Vonbrunn E, Knöll A, Hermann M, Büttner-Herold M, Daniel C, Hartmann A. COVID-19-Auswirkungen auf die Niere [COVID-19 effects on the kidney]. Pathologe. 2021; 42(2):183-187.
Seeber C, Popp M, Meerpohl J, et al . COVID-19-Pandemie: Präferenzen und Barrieren für die Disseminierung von Evidenzsynthesen. Anaesthesist. 2021;      [DOI] 
Polotzek K, Karch A, Karschau J, Wagner M, Lünsmann B, Menk M, Römmele C, Schmitt J. COVID-19-Pandemie: Regionale Steuerung der Patienten. Dtsch Arztebl International. 2021; 118(3):84—.
Ihlow J, Seelhoff A, Corman VM, Gruber AD, Dökel S, Meinhardt J, Radbruch H, Späth-Schwalbe E, Elezkurtaj S, Horst D, Herbst H. COVID-19: a fatal case of acute liver failure associated with SARS-CoV-2 infection in pre-existing liver cirrhosis. BMC Infectious Diseases. 2021 Sep.; 21(1):901.      [DOI]      [File] 
Ritschel N, Schneider N, Dittmayer C, Franz J, Thomas C, Silva Boos G, Sohrabi K, Schänzer A, Németh A, „CNS-COVID19“ D, COVID-19“ „PNR. COVID-19: Auswirkungen auf das zentrale und periphere Nervensystem. Der Pathologe. 2021 Mar.; 42(2):172—182.      [DOI]      [File] 
Ackermann M, Werlein C, Länger F, Kühnel MP, Jonigk DD. COVID-19: Auswirkungen auf Lunge und Herz. Der Pathologe. 2021 Mar.; 42(2):164—171.      [DOI]      [File] 
Werlein C, Länger F, Kühnel MP, Jonigk DD. COVID-19: Auswirkungen auf Lunge und Herz [COVID-19: effects on the lungs and heart]. Pathologe. 2021; 42(2):164-171.
Greuel S, Ihlow J, Dragomir M, Streit S, Corman VM, Haberbosch L, Winkler D, Meinhardt J, Aschman T, Schneider J, Trotsyuk I, Kunze CA, Maurer L, Radbruch H, Heppner FL, Horst D, Elezkurtaj S. COVID-19: Autopsy findings in six patients between 26 and 46 years of age. International Journal of Infectious Diseases. 2021 Jul.; 108274—281.      [DOI]      [File] 
Loyal L, Braun J, Henze L, Kruse B, Dingeldey M, Reimer ea. Cross-reactive CD4(+) T cells enhance SARS-CoV-2 immune responses upon infection and vaccination. Science. 2021;
Loyal L, et al . Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination. Science (New York, N.Y.). 2021;      [DOI] 
Metzendorf M. Das Cochrane COVID-19 Studienregister – eine studienbasierte, strukturierte Datenbank zur effizienten Identifizierung wissenschaftlicher Evidenz. GMS Med Bibl Inf. 2021 Sep.; 21(1-2):Doc09.      [DOI] 
Edler C, Klein A, Schröder A, Sperhake J, Ondruschka B. Deaths associated with newly launched SARS-CoV-2 vaccination (Comirnaty®). Leg Med (Tokyo). 2021 Jul.; 51101895.      [DOI] 
Edler C, Klein A, Schröder AS, Sperhake J, Ondruschka B. Deaths associated with newly launched SARS-CoV-2 vaccination (Comirnaty®). Legal Medicine. 2021 Jul.; 51101895.      [DOI]      [File] 
Trimpert J, et al . Deciphering the Role of Humoral and Cellular Immune Responses in Different COVID-19 Vaccines-A Comparison of Vaccine Candidate Genes in Roborovski Dwarf Hamsters. Viruses. 2021; 13      [DOI] 
Schwabenland M, Salié H, Tanevski J, Killmer S, Lago M, Schlaak A, Mayer L, Matschke J, Püschel K, Fitzek A, Ondruschka B, Mei H, Boettler T, Neumann-Haefelin C, Hofmann M, Breithaupt A, Genc N, Stadelmann C, Saez-Rodriguez J, Bronsert P, Knobeloch K, Blank T, Thimme R, Glatzel M, Prinz M, Bengsch B. Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions. Immunity. 2021; 54(7):1594-1610.e11.      [DOI] 
Schwabenland M, Salié H, Tanevski J, Killmer S, Lago MS, Schlaak AE, Mayer L, Matschke J, Püschel K, Fitzek A, Ondruschka B, Mei HE, Boettler T, Neumann-Haefelin C, Hofmann M, Breithaupt A, Genc N, Stadelmann C, Saez-Rodriguez J, Bronsert P, Knobeloch K, Blank T, Thimme R, Glatzel M, Prinz M, Bengsch B. Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions. Immunity. 2021 Jul.; 54(7):1594—1610.e11.      [DOI]      [File] 
Englert H, Rangaswamy C, Deppermann C, Sperhake J, Krisp C, Schreier D, Gordon E, Konrath S, Haddad M, Pula G, Mailer RK, Schlüter H, Kluge S, Länger F, Püschel K, Panousis K, Stavrou EX, Maas C, Renné T, Frye M. Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation. EBioMedicine. 2021 May; 67103382.      [DOI]      [File] 

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