Publications in the NUM

Mirus M, Dietze A, Tiebel O, Beyer-Westendorf J, Grottke O, Tesch F, Spieth PM, Heubner L. Viscoelastic point-of-care testing for monitoring unfractionated heparin in critically ill patients: a prospective observational study comparing ClotPro™ IN/HI-Test, aPTT and Anti-Xa activity. BMC Anesthesiol.. 2026 Mar.; 26(1):

Leberzammer J, Abplanalp WT, Grikscheit K, Solomonidis EG, Glaser S, Schuhmacher B, Merten M, Jeremijev G, Wilken-Schmitz A, Korth L, John D, G"unther S, Kuenne C, Looso M, Valasarajan C, Benes V, Jung F, Niehaus V, Anton G, Stellbrink C, R"ommele C, G"opel S, Pullamsetti SS, Vehreschild J, Vehreschild M, Ciesek S, Leistner DM, Zeiher AM, Dimmeler S, Cremer S. Atherosclerosis licenses for an exceeding immune response in COVID-19 disease by interferon priming in circulating myeloid cells. Cardiovasc. Res.. 2026 Feb.; 122(1):81—97.

Lindholz M, Bülow R, Schoots IG, Kölln M, Nolte S, Baumgärtner GL, Chenot J, Schmidt CO, Burchardt M, Nauck M, Völzke H, Wielpütz MO, Penzkofer T, Hosten N, Hamm CA. Clinical and Liquid Biomarkers of 20-Year Prostate Cancer Risk in Men Aged 45 to 70 Years. JAMA network open. 2026 Feb.; 9(2):e2556732.      [DOI]      [File] 

Düsing H, Otto R, Raschke M, Walcher F, Drynda S, Waydhas C, Oeckenpöhler S. Orthopädie und Unfallchirurgie in deutschen Notaufnahmen. Die Unfallchirurgie. 2026 Feb.;      [DOI]      [File] 

Riera-Marin M, Kleiss J, Aubanell A, Antolin A, Moreno-Vedia J, Rodriguez-Comas J, O K S, May M, Garcia-Lopez J, Galdran A, González Ballester MA. A MultiRater MultiOrgan Abdominal CT Dataset for Calibration Analysis and Uncertainty Modeling in Segmentation. Scientific data. 2026 Jan.; 13(1):156.      [DOI]      [File] 

Abolhassani A, Alawathurage TM, Schmidt A, Brand F, Kilarski LL, Altmann H, Dahl E, Frank S, G"opel S, Hanses F, Hellmuth JC, Herr C, Kaasch AJ, Kobbe R, Konik MJ, Pink I, R"ommele C, Rupp J, Scheer CS, Schneider MA, Stellbrink C, Stubbe HC, Tepasse P, Teufel A, Vadasz I, Vehreschild MJGT, Witzenrath M, Anton G, Br"ohl I, Herold S, Illig T, Jiru-Hillmann S, Krawitz P, Mitrov L, Philipsen A, P"utz SM, Noethen MM, Nuernberg P, Reese J, Riess O, Schreiber S, Schultze J, Steinbeis F, Vehreschild JJ, Wildberg C, Ludwig KU, Schulte EC. Genetic contribution to severe COVID-19 in adults under 60 years without major comorbidities in the German National Pandemic Cohort Network (NAPKON). Hum. Genomics. 2026 Jan.; 20(1):23.

Benesch Vidal ML, Haack A, Anders-Lohner S, Munzinger J, Keil LD, Albrecht JN, Borger L, Twerenbold R, Ondruschka B, Blankenberg S, Becher PM. Implementation of post-mortem examinations within a large population-based cohort: results from the Hamburg City Health Study. Clinical Research in Cardiology. 2026 Jan.; Epub ahead of print.      [DOI]      [File] 

Yilmaz EY, Schmidt R, Heidemann L, He Y, Liu Y, Sulejmani O, Müller DN, Wilhelm A, Auer TA, Hamm CA, Abosabie SAS, Abosabie SA, Gebauer B, Savic LJ. Local and systemic cytokine signatures for outcome prediction after transarterial chemoembolization in hepatocellular carcinoma. Theranostics. 2026; 16(11):6099-6112.      [DOI]      [File] 

Eminovic S, Levita B, Schmidt R, Lindholz M, Desser D, Penzkofer T, Wattjes MP, Nawabi J. Open-source versus proprietary large language models for academic writing in medicine: A controlled evaluation of DeepSeek-R1 and ChatGPT-o1 in neuroradiology. Digital health. 2026; 1220552076261464745.      [DOI]      [File] 

Misera L, Nebelung S, Carrero ZI, Bressem K, Ligero M, Kühn J, Hoffmann R, Truhn D, Kather JN. Reducing manual workload in CT and MRI annotation with the Segment Anything Model 2. BMC medical imaging. 2026 Jan.; 26(1):54.      [DOI]      [File] 

Bienzeisler J, Hertwig MK, Heidemeyer H, Alhaskir M, Majeed RW, Kombeiz A, Hoy W, Huening S, Goettgens F, Unterkofler J, Rademacher S, Panagiotidis D, Marewski V, Sommer A, Schirrmeister W, Walcher F, Otto R, Ehrentreich S, Beyel HH, Peeva V, Schwanen CT, Pegoraro M, Zoch-Lesniak B, Pollmanns J, Wittmar R, Stillfried DG, Röhrig R, Beckers SK, Aalst WMP, Brokmann JC. Trans-sectoral patient pathways in urgent and emergency care (TRANSPARENT study): protocol for a prospective, mixed-methods study in Germany. BMJ Open. 2026; 16(2):      [DOI] 

Wolf D, Hillenhagen H, Taskin B, Bäuerle A, Beer M, Götz M, Ropinski T. Your other Left! Vision-Language Models Fail to Identify Relative Positions in Medical Images. Lecture Notes in Computer Science. 2026; 691-701.      [DOI]      [File] 

TODO

Bartenschlager C, Frey R, Freitag M, et al . Managing hospital visitor admission during Covid-19: A discrete-event simulation by the data of a German University Hospital.      [DOI] 

Klein C, Borsche M, Balck A, et al . One-year surveillance of SARS-CoV-2 transmission of the ELISA Cohort: A model for population-based monitoring of infection risk. Science Adv.

Jukic M, Dunkel A, Haller B, et al . Persistent loss of smell and taste perception in subjects with anti-SARS-CoV-2 antibodies.

Kahn M, Zellmer S, Ebigbo A, et al . Progress of the vaccination campaign among HCW in AGP in Germany.

Wulff A, Biermann P, von Landesberger T, et al . A Smart Infection Control System for COVID-19 Infections in Hospitals. In: Conference on 66. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS) 2021.     [File] 

Schramm A, Raidt J, Riepenhausen S, Nygaard CMT, Tenardi-Wenge R, Qvist T, Witt P, Storck M, Olbrich H, Nielsen KG, Omran H. Limitations of PICADAR as a diagnostic predictive tool for primary ciliary dyskinesia. Front. Mol. Biosci.. 2025 Dec. 8; 12(1691758):1691758.

Hamdan A, El-Amri Y, Heinrich F, Mohamed OAA, Sepulveda-Falla D, Glatzel M, Matschke J, Krasemann S. ApoE4 Homozygosity Is Associated With Increased Microglia Activation in Fatal COVID-19. Neuropathology: Official Journal of the Japanese Society of Neuropathology. 2025 Dec.; 45(6):e70033.      [DOI] 

Rempe M, Heine L, Seibold C, Hörst F, Kleesiek J. De-identification of medical imaging data: a comprehensive tool for ensuring patient privacy.. European radiology. 2025 Dec.;      [DOI] 

Rothoeft T, Hoffmann AT, Maier C, Denz R, Kobbe R, Friedrichs A, Behrens GMN, Behrens P, Berner R, Caliebe A, Denkinger CM, Giesbrecht K, Hojenski L, Hovardovska O, Dopfer-Jablonka A, Iatseniuk O, Kaasch AJ, Kraus M, Mitrov L, Nauck M, Miranda SN, Scherer M, Schmiedel Y, Stahl D, Timmesfeld N, Toepfner N, Vehreschild J, Wohlgemuth WA, Petersmann A, Vehreschild MJGT, Brinkmann F. Performance of whole blood interferon-γ release assays in SARS-CoV-2 and tuberculosis is age dependent. Infection. 2025 Dec.; 53(6):2669-2680.      [DOI]      [File] 

Buchka S, Hapfelmeier A, Kirschke JS, Steuerwald V, Naumann M, Soto-Rey I, Rohr SO, Kramer F, Behrens L, Oswald E, Kümpfel T, Zimmermann H, Hoffmann VS, Hagedorn M, Albashiti F, Krumbholz M, Ziemann U, Kohlbacher O, Sailer B, Braunmüller V, Biergans S, Herr M, Ernemann U, Bürkle E, Bender B, Daul A, Ruff C, Römhild J, Wiestler B, Sepp D, Spengler H, Pallaoro P, Boeker M, Kohlmayer F, Dehmelt V, Berthele A, Mühlau M, Uibel P, Wauschkuhn J, Kuhn K, Senel M, Vardakas I, Taranu D, Kestler HA, Sollmann N, Ön BI, Bilger S, Mansmann U, Bayas A, Havla J, Kowarik MC, Tumani H, and BH. External validation of a multiple sclerosis treatment decision score using data from the ProVal-MS cohort study. Therapeutic Advances in Neurological Disorders. 2025 Nov. 21; 1817562864251391095.      [DOI] 

Graefe ASL, Rehburg F, Alkarkoukly S, Danis D, Gr"onke A, H"ubner MR, Bartschke A, Debertshäuser T, Klopfenstein SAI, Sass J, Fleck J, Rehberg M, Zsch"untzsch J, Nyoungui EF, Kalashnikova T, Murgu\'ıa-Favela L, Derfalvi B, Wright NAM, Moosa S, Ogishima S, Semler O, Wiegand S, K"uhnen P, Mungall CJ, Haendel MA, Robinson PN, Thun S, Beyan O. RareLink: scalable REDCap-based framework for rare disease interoperability linking international registries to FHIR and Phenopackets. npj Genomic Medicine. 2025 Nov. 18; 10(1):72.

Arruda Botelho M, Ata Baykara C, Burak "Unal A, Pfeifer N, Akg"un M. Privacy-preserving AUC computation in distributed machine learning with PHT-meDIC. PLOS Digital Health. 2025 Nov. 13; 4(11):e0000753.

Misera L, Schiemann L, Kather JN, Hoffmann R, Kühn J, Schön F. 351P Non-invasive prediction of liver tumor entity from CT using artificial intelligence. ESMO Real World Data and Digital Oncology. 2025 Nov.; 10100547.      [DOI]      [File] 

Lackner NA, Karius A, Brandt T, Ott OJ, Putz F, Strnad V, May MS, Fietkau R, Bert C, Szkitsak J. Automated quality assurance of imaging dose and protocol adherence in computed tomography radiotherapy planning using TotalSegmentator-based segmentation.. Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]. 2025 Nov.;      [DOI] 

Baum JHJ, Dörre A, Boender TS, Heldt K, Wilking H, Drynda S, Erdmann B, Grashey R, Grupp C, Habbinga K, Hamelmann E, Heining A, Höger-Schmidt H, Kill C, Reichert F, Riße J, Schilling T, Group AR, Baacke M, Bauer J, Bernhard M, Bienzeisler J, Blaschke S, Brokmann J, Burst V, Busch H, Dormann H, Duesberg C, Ehrentreich S, Gries A, Händl T, Handmann E, Hans F, Hanses F, Henke T, Klein M, Hofmann T, Karg M, Kleinekorth J, Kombeiz A, Kumle B, Kümpers P, Lewejohann C, Dinse-Lambracht A, Lucas B, Mach C, Majeed RW, Neubauer J, Otto R, Peschel T, Pfeufer N, Röhrig R, Schirrmeister W, Schunk D, Stahl W, Stefani H, Triefenbach L, Uirich B, Walcher F, Wehler M, Wenderoth H, Wolfrum S, Wrede C, Zimmermann M, Schranz M. Establishing and validating syndromic surveillance of gastrointestinal infections using routine emergency department data, Germany, 2019–2023. Scientific Reports. 2025 Nov.; 15(1):38281.      [DOI]      [File] 

Woo S, Russo L, Withey SJ, Dehghanpour A, García-Figueiras R, Schoots IG, Petralia G, Lakhani A, Penzkofer T, Pecoraro M, Wu C, Walz J, Eiber M, Fendler WP, Gillessen S, Perez-Lopez R, Lecouvet FE, Barwick TD, Padhani AR. ESUR: Opportunities for PSMA-PET/CT and whole-body MRI in advanced prostate cancer.. European radiology. 2025 Nov.;      [DOI] 

Ehrentreich S, Kamer N, Drynda S, Otto R, Walcher F, Lucas B. Impact of government pyrotechnics ban on emergency department usage rates around the turn of the years. European Journal of Trauma and Emergency Surgery. 2025 Nov.; 51(1):337.      [DOI]      [File] 

Arruda Botelho M, Ata Baykara C, Burak "Unal A, Pfeifer N, Akg"un M. Privacy-preserving AUC computation in distributed machine learning with PHT-meDIC. PLOS Digit. Health. 2025 Nov.; 4(11):e0000753.

Weber F, Pavel V, Müller M, Boor P, Läber L, Stillfried S, Buechler C. Profiles of PCSK9, SREBP-2, and histopathology in COVID-19 and non-COVID-19 critical illness. BMC Infectious Diseases. 2025 Nov.; 25(1):1573.      [DOI]      [File] 

Von Stillfried S. Von der Obduktion zur Translation. Die Pathologie. 2025 Nov.; 47(Suppl 1):62-67.      [DOI]      [File] 

Hoffmann T, Teichgräber U, Lassen-Schmidt B, Renz D, Brüheim LB, Weise T, Krämer M, Böttcher J, Güttler F, Wolf G, Pfeil A. AI-based HRCT quantification reveals DLCO and TLC as key determinants of ILD severity in connective tissue diseases.. RMD open. 2025 Oct.;      [DOI] 

Thaploo D, Schmill L, Behrend N, Gerlach S, Fogel C, Ruß A, Lieb W, Schreiber S, Maetzler W, Maetzler C, Krawczak M, Weinert N, Bahmer T, Raquib S, Fiedler K, Vehreschild JJ, Jansen O, Mignot C, Aludin S, Laudien M. Alterations of the amygdala in post-COVID olfactory dysfunction.. Scientific reports. 2025 Oct.;      [DOI] 

Riera-Marin M, O K S, Rodriguez-Comas J, May MS, Pan Z, Zhou X, Liang X, Erick FX, Prenner A, Hémon C, Boussot V, Dillenseger J, Nunes J, Qayyum A, Mazher M, Niederer SA, Kushibar K, Martín-Isla C, Radeva P, Lekadir K, Barfoot T, Garcia Peraza Herrera LC, Glocker B, Vercauteren T, Gago L, Englemann J, Kleiss J, Aubanell A, Antolin A, Garcia-Lopez J, González Ballester MA, Galdran A. Calibration and Uncertainty for multiRater Volume Assessment in multiorgan Segmentation (CURVAS) challenge results. Computers in biology and medicine. 2025 Oct.; 197(Pt B):111024.      [DOI]      [File] 

Lindholz M, Burdenski A, Ruppel R, Schulze-Weddige S, Baumgärtner GL, Schobert I, Haack A, Eminovic S, Milnik A, Hamm CA, Frisch A, Penzkofer T. Comparing large language models and text embedding models for automated classification of textual, semantic, and critical changes in radiology reports.. European journal of radiology. 2025 Oct.;      [DOI] 

Schluessel S, Mueller B, Tausendfreund O, Rippl M, Deissler L, Martini S, Schmidmaier R, Stoecklein S, Ingrisch M, Blaschke S, Brandhorst G, Spieth P, Lehnert K, Heuschmann P, Miranda SMN, Drey M. Impact of sarcopenia and obesity on mortality in older adults with SARS-CoV-2 infection: automated deep learning body composition analysis in the NAPKON-SUEP cohort.. Infection. 2025 Oct.;      [DOI] 

Levita B, Eminovic S, Lüdemann WM, Schnapauff D, Schmidt R, Haack A, Dell'Orco A, Nawabi J, Penzkofer T. Large language models for patient education prior to interventional radiology procedures: a comparative study.. CVIR endovascular. 2025 Oct.;      [DOI] 

Trif N, Kloth C, Büttner SM, Egenrieder N, Wolf D, Schmidt SA, Vogele D, Sollmann N, Flack F, Peters L, Grüner B, Jungwirth B, Stenger S, Stamminger T, Beer M. Semi-quantitative software evaluation of COVID-19 CT examinations-correlation with clinical parameters.. Journal of thoracic disease. 2025 Oct.;      [DOI] 

Lohr C, Faller J, Riedel A, Nguyen HM, Wolfien M, Hofenbitzer J, Modersohn L, Romberg J, Prasser F, Omeirat J, Wen Y, Galusch O, Hahn U, Seiferling M, Dieterich C, Kl"ugl P, Matthies F, Kind J, Boeker M, L"offler M, Meineke F. GeMTeX's DE-identification in action: Lessons learned & devil's details. In: Studies in Health Technology and Informatics. IOS Press; 2025 Sep. 3.

Neidhardt M, Bosse L, Raudonis V, Allgoewer K, Heinemann A, Ondruschka B, Schlaefer A. A Digital Twin for Robotic Post Mortem Tissue Sampling using Virtual Reality. IEEE Robotics and Automation Letters. 2025 Sep.; 10(11):11141-11147.      [DOI]      [File] 

Matschke J, Huter T, Renné T, Lütgehetmann M, Glatzel M, Ondruschka B. Fatal Cerebral Venous Sinus Thrombosis and Thrombocytopenia due to Anti-PF4 Disorder Following Adenovirus Infection in a 3-year-old Boy. Thrombosis and Haemostasis. 2025 Sep.; 125(9):919-922.      [DOI]      [File] 

Schröder AS, Ondruschka B. Krematoriumsleichenschau: eine rechtsmedizinische Betrachtung im Kontext der COVID-19-Pandemie. Rechtsmedizin. 2025 Sep.; 35344–350.      [DOI]      [File] 

Denner S, Zimmerer D, Bounias D, Bujotzek M, Xiao S, Stock R, Kausch L, Schader P, Penzkofer T, Jäger PF, Maier-Hein K. Leveraging foundation models for content-based image retrieval in radiology. Computers in biology and medicine. 2025 Sep.; 196(Pt A):110640.      [DOI]      [File] 

Krueger MB, Werncke T, Eicke M, Schwerk N, Eckstein J, Huisinga C, Panknin C, Shin H, Silchmüller FJ, Schultze-Florey RE, Hansen G, Wacker F, Hellms S, Renz DM. Photon-counting Detector CT Enables Pediatric Low-dose Chest Imaging With Further Reduction of Radiation Exposure.. Investigative radiology. 2025 Sep.;      [DOI] 

Bienzeisler J, Kombeiz A, Heidemeyer H, Hertwig M, Erdmann B, Pegoraro M, Ehrentreich S, Eder PA, Mosebach J, Rashid A, Majeed RW. Embedding FHIR in Medical PDF: A Migration Path for Interoperable Documentation. In: Röhrig, Rainer and Ganslandt, Thomas and Jung, Klaus and Kock-Schoppenhauer, Ann-Kristin and König, Jochem and Sax, Ulrich and Sedlmayr, Martin and Spreckelsen, Cord and Zapf, Antonia, editors. Studies in Health Technology and Informatics. IOS Press; 2025 Sep..      [DOI]      [File] 

Macedo M, Wiedekopf J, Hillmer T, Schreiweis B, Saalfeld S, Ulrich H. From text to knowledge: An end-to-end extraction pipeline for clinical information. Stud. Health Technol. Inform.. 2025 Aug. 8; 3291074—1078.

Bronsch T, Anywar M, Kinast B, Ulrich H, Macedo M, Kruse J, Behrend P, Schreiweis B. Implementation of a patient consent management at a German medical data integration center. Stud. Health Technol. Inform.. 2025 Aug. 8; 3291626—1627.

Schulze-Weddige S, Fehrenbach U, Kolck J, Ruppel R, Baumgärtner GL, Lindholz M, Schobert IT, Haack A, Jann H, Mogl M, Geisel D, Wiedenmann B, Penzkofer T. Automatic 3D Tracking of Liver Metastases: Follow-Up Assessment of Cancer Patients in Contrast-Enhanced MRI.. Bioengineering (Basel, Switzerland). 2025 Aug.;      [DOI]