Publications in the NUM

Kottlors J, Große Hokamp N, Fervers P, Bremm J, Fichter F, Persigehl T, Safarov O, Maintz D, Tritt S, Abdullayev N. Early extrapulmonary prognostic features in chest computed tomography in COVID-19 pneumonia: Bone mineral density is a relevant predictor for the clinical outcome - A multicenter feasibility study. Bone. 2021 Mar.; 144115790.      [DOI]      [File] 

Subbarayan K, Ulagappan K, Wickenhauser C, Bachmann M, Seliger B. Immune Interaction Map of Human SARS-CoV-2 Target Genes: Implications for Therapeutic Avenues. Frontiers in Immunology. 2021 Mar.; 12597399.      [DOI]      [File] 

Strobl S, Roth W. Internationale wissenschaftliche Publikationsaktivität zu COVID-19. Der Pathologe. 2021 Mar.; 42(2):224—230.      [DOI]      [File] 

Stillfried S, Acker T, Aepfelbacher M, Baretton G, Bülow RD, Bürrig K, Holtherm H, Jonigk D, Knüchel R, Majeed RW, Röhrig R, Wienströer J, Boor P. Kooperatives Vorgehen der Pathologie und Neuropathologie in der COVID-19-Pandemie. Der Pathologe. 2021 Mar.; 42(2):216—223.      [DOI]      [File] 

Englisch CN, Tschernig T, Flockerzi F, Meier C, Bohle RM. Lesions in the lungs of fatal corona virus disease Covid-19. Annals of Anatomy = Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft. 2021 Mar.; 234151657.      [DOI] 

Stillfried S, Boor P. Nachweismethoden von SARS-CoV-2 in Gewebe. Der Pathologe. 2021 Mar.; 42(2):208—215.      [DOI]      [File] 

Boor P, Eichhorn P, Hartmann A, Lax SF, Märkl B, Menter T, Skok K, Slotta-Huspenina J, Stillfried S, Tzankov A, Weirich G. Praktische Aspekte von COVID-19-Obduktionen. Der Pathologe. 2021 Mar.; 42(2):197—207.      [DOI]      [File] 

Althaus K, Marini I, Zlamal J, Pelzl L, Singh A, Häberle H, Mehrländer M, Hammer S, Schulze H, Bitzer M, Malek N, Rath D, Bösmüller H, Nieswandt B, Gawaz M, Bakchoul T, Rosenberger P. Antibody-induced procoagulant platelets in severe COVID-19 infection. Blood. 2021 Feb.; 137(8):1061—1071.      [DOI]      [File] 

Ihlow J, Michaelis E, Greuel S, Heynol V, Lehmann A, Radbruch H, Meinhardt J, Miller F, Herbst H, Corman VM, Westermann J, Bullinger L, Horst D, Brünneck A, Elezkurtaj S. B cell depletion and signs of sepsis-acquired immunodeficiency in bone marrow and spleen of COVID-19 deceased. International Journal of Infectious Diseases. 2021 Feb.; 103628—635.      [DOI]      [File] 

Elezkurtaj S, Greuel S, Ihlow J, Michaelis EG, Bischoff P, Kunze CA, Sinn BV, Gerhold M, Hauptmann K, Ingold-Heppner B, Miller F, Herbst H, Corman VM, Martin H, Radbruch H, Heppner FL, Horst D. Causes of death and comorbidities in hospitalized patients with COVID-19. Scientific Reports. 2021 Feb.; 11(1):4263.      [DOI]      [File] 

Hofman P, Ilié M, Chamorey E, Brest P, Schiappa R, Nakache V, Antoine M, Barberis M, Begueret H, Bibeau F, Bonnetaud C, Boström P, Brousset P, Bubendorf L, Carvalho L, Cathomas G, Cazes A, Chalabreysse L, Chenard M-, Copin M-, Côté J-, Damotte D, Leval L, Delongova P, Montpreville V, Muret A, Dema A, Dietmaier W, Evert M, Fabre A, Forest F, Foulet A, Garcia S, Garcia-Martos M, Gibault L, Gorkiewicz G, Jonigk D, Gosney J, Hofman A, Kern I, Kerr K, Kossai M, Kriegsmann M, Lassalle S, Long-Mira E, Lupo A, Mamilos A, Matěj R, Meilleroux J, Ortiz-Villalón C, Panico L, Panizo A, Papotti M, Pauwels P, Pelosi G, Penault-Llorca F, Pop O, Poté N, Cajal SRY, Sabourin J-, Salmon I, Sajin M, Savic-Prince S, Schildhaus H-, Schirmacher P, Serre I, Shaw E, Sizaret D, Stenzinger A, Stojsic J, Thunnissen E, Timens W, Troncone G, Werlein C, Wolff H, Berthet J-, Benzaquen J, Marquette C-, Hofman V, Calabrese F. Clinical and molecular practice of European thoracic pathology laboratories during the COVID-19 pandemic. The past and the near future. ESMO Open. 2021 Feb.; 6(1):100024.      [DOI]      [File] 

Nörz D, Hoffmann A, Aepfelbacher M, Pfefferle S, Lütgehetmann M. Clinical evaluation of a fully automated, laboratory-developed multiplex RT-PCR assay integrating dual-target SARS-CoV-2 and influenza A/B detection on a high-throughput platform. Journal of Medical Microbiology. 2021 Feb.; 70(2):001295.      [DOI]      [File] 

Zhao Y, Kilian C, Turner J, Bosurgi L, Roedl K, Bartsch P, Gnirck A, Cortesi F, Schultheiß C, Hellmig M, Enk LUB, Hausmann F, Borchers A, Wong MN, Paust H, Siracusa F, Scheibel N, Herrmann M, Rosati E, Bacher P, Kylies D, Jarczak D, Lütgehetmann M, Pfefferle S, Steurer S, Zur-Wiesch JS, Puelles VG, Sperhake J, Addo MM, Lohse AW, Binder M, Huber S, Huber TB, Kluge S, Bonn S, Panzer U, Gagliani N, Krebs CF. Clonal expansion and activation of tissue-resident memory-like Th17 cells expressing GM-CSF in the lungs of severe COVID-19 patients. Science Immunology. 2021 Feb.; 6(56):eabf6692.      [DOI] 

Holz J. Der Erfolg Vietnams im Kampf gegen das Virus. Südostasien. Zeitschrift für Politik, Kultur, Dialog. 2021 Feb.;

Meinhardt J, Radke J, Dittmayer C, Franz J, Thomas C, Mothes R, Laue M, Schneider J, Brünink S, Greuel S, Lehmann M, Hassan O, Aschman T, Schumann E, Chua RL, Conrad C, Eils R, Stenzel W, Windgassen M, Rößler L, Goebel H, Gelderblom HR, Martin H, Nitsche A, Schulz-Schaeffer WJ, Hakroush S, Winkler MS, Tampe B, Scheibe F, Körtvélyessy P, Reinhold D, Siegmund B, Kühl AA, Elezkurtaj S, Horst D, Oesterhelweg L, Tsokos M, Ingold-Heppner B, Stadelmann C, Drosten C, Corman VM, Radbruch H, Heppner FL. Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19. Nature Neuroscience. 2021 Feb.; 24(2):168—175.      [DOI]      [File] 

Holz J. Singapurs gebrochenes Versprechen. Südostasien. Zeitschrift für Politik, Kultur, Dialog. 2021 Feb.;

Spogis J, Hagen F, Thaiss WM, Hoffmann T, Malek N, Nikolaou K, Berg CP, Singer S, Bösmüller H, Kreth F, Kaufmann S. Sonographic findings in coronavirus disease-19 associated liver damage. PLOS ONE. 2021 Feb.; 16(2):e0244781.      [DOI]      [File] 

Nicolai L, Leunig A, Brambs S, Kaiser R, Joppich M, Hoffknecht M, Gold C, Engel A, Polewka V, Muenchhoff M, Hellmuth JC, Ruhle A, Ledderose S, Weinberger T, Schulz H, Scherer C, Rudelius M, Zoller M, Keppler OT, Zwißler B, Bergwelt‐Baildon M, Kääb S, Zimmer R, Bülow RD, Stillfried S, Boor P, Massberg S, Pekayvaz K, Stark K. Vascular neutrophilic inflammation and immunothrombosis distinguish severe COVID‐19 from influenza pneumonia. Journal of Thrombosis and Haemostasis. 2021 Feb.; 19(2):574—581.      [DOI]      [File] 

Jansky M, Schade F, Rieder N, Lohrmann D, Gebel C, Stahl D. ‘It felt like a black hole, great uncertainty, but we have to take care for our patients’–Qualitative findings on the effects of the COVID-19 pandemic on specialist palliative home care. PLOS ONE. 2021; 16(12):e0260767.      [DOI] 

Schloesser K, Simon ST, Pauli B, Stahl D. “Saying goodbye all alone with no close support was difficult”- Dying during the COVID-19 pandemic: an online survey among bereaved relatives about end-of-life care for patients with or without SARS-CoV2 infection. BMC Health Serv Res. 2021; 21(998):      [DOI] 

Gebel C, Kloppenburg L, Jansky MK, Nauck F, Schade F, Weddin U. „Es waren Kreativität und Umdenken erforderlich.“ Auswirkungen der COVID-19 Pandemie auf die spezialisierte ambulante Palliativversorgung (SAPV). Eine bundesweite Onlinebefragung. Gesundheitswesen. 2021;      [DOI] 

Reichardt M, Moller Jensen P, et al . 3D virtual histopathology of cardiac tissue from Covid-19 patients based on phase-contrast X-ray tomography. Elife. 2021; 10e71359.      [DOI] 

Vesper N, et al . A Barcoded Flow Cytometric Assay to Explore the Antibody Responses Against SARS-CoV-2 Spike and Its Variants. Frontiers in immunology. 2021; 12      [DOI] 

Iftekhar EN, Priesemann V, Balling R, Bauer S, Beutels P, Valdez AC, Cuschieri S, Czypionla T, Dumpis U, Glaab E, Grill E, Hanson C, Hotulainen P, Klimek P, Kretzschmar M, Krüger T, Krutzinna J, Low N, Machado H, Martins C, McKee M, Mohr SB, Nassehi A, Perc M, Petelos E, Pickersgrill M, Prainsack B, Rocklöv J, Schernhammer E, Staines A, Szczurek E, Tsiodras S, Van Gucht S, Willeit P. A look into the future of the COVID-19 pandemic in Europe: an expert consultation. The Lancet Regional Health-Europe. 2021; 8100185.      [DOI] 

Wang Z, Cryar A, Lemke O, Ludwig D, Tober-Lau P, Helbig ea. A multiplex protein panel assay determines disease severity and is prognostic about outcome in COVID-19 patients. medRxiv. 2021;      [DOI] 

Mahoney M, et al . A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells. Proceedings of the National Academy of Sciences of the United States of America. 2021; 118      [DOI] 

Peter AS, et al . A pair of non-competing neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection model. European journal of immunology. 2021;      [DOI] 

Peter AS, Roth E, Schulz S, et al . A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS‐CoV‐2 infection model. Eur J Immunol. 2021;      [DOI]      [File] 

Schuh W, et al . A surrogate cell-based SARS-CoV-2 spike blocking assay. European journal of immunology. 2021;      [DOI] 

Demichev V, et al . A time-resolved proteomic and prognostic map of COVID-19. Cell Systems. 2021;      [DOI] 

Demichev V, Tober-Lau P, Lemke O, Nazarenko T, Thibeault C, Whitwell H, Röhl A, Freiwald A, Szyrwiel L, Ludwig D, Stahl D. A time-resolved proteomic and prognostic map of COVID-19. Cell Syst. 2021; 12(8):780—794.e7.      [DOI] 

Demichev V, Tober-Lau P, Lemke O, Nazarenko T, Thibeault C, Whitwell ea. A time-resolved proteomic and prognostic map of COVID-19. Cell Syst. 2021; 12780—+.

Brümmer L, Katzenschlager S, Gaeddert M, Stahl D. Accuracy of novel antigen rapid diagnostics for SARS-CoV-2: A living systematic review and meta-analysis. PLOS Medicine. 2021; 18(8):      [DOI]      [File] 

Stanifer ML, Boulant S. Adapting Gastrointestinal Organoids for Pathogen Infection and Single Cell Sequencing under Biosafety Level 3 (BSL-3) Conditions. JoVE. 2021; (166):e62857.      [DOI] 

Mürbe D, Kriegel M, Lange J, et al . Aerosol emission in professional singing of classical music. Sci Rep. 2021; 11      [DOI] 

Mürbe D, Kriegel M, Lange J, et al . Aerosol emission of adolescents voices during speaking, singing and shouting. PLoS ONE. 2021; 16(2):      [DOI] 

Schwartz J, Reuters MC, Schallenburger M, Stahl D. Allgemeine Palliativversorgung in Pandemiezeiten. Onkologe. 2021; 27686-690.      [DOI] 

Weber J, Tielker JM, Kamandi N, et al . Ambulante Betreuung onkologischer Patienten in palliativer Behandlungssituation und ihrer Angehörigen in der COVID-19-Pandemie. Onkologe. 2021; 27783-789.      [DOI] 

Priesemann V, Balling R, Brinkmann MM, Ciesek S, Czypionka T, Eckerle I, Giordano G, Hanson C, Hel Z, Hotulainen P, Klimek P, Nassehi A, Peichl A, Perc M, Petelos E, Prainsack B, Szczurek E. An action plan for pan-European defence against new SARS-CoV-2 variants. The Lancet. 2021; 397(10273):469—470.      [DOI] 

Bagheri G, Thiede B, Hejazi B, et al . An upper bound on one-to-one exposure to infectious human respiratory particles. PNAS. 2021; 118(49):      [DOI] 

Schulze J, Mache C, Balazs A, Frey D, Niemeyer D, Olze ea. Analysis of SARS-CoV-2 replication in explant cultures of the human upper respiratory tract reveals broad tissue tropism of wild-type and B.1.1.7 variant viruses. J Infect Dis. 2021;      [DOI] 

Renn M, Bartok E, Zillinger T, Hartmann G, Behrendt R. Animal models of SARS-CoV-2 and COVID-19 for the development of prophylactic and therapeutic interventions. Pharmacology & Therapeutics. 2021; 107931.      [DOI] 

Gagiannis D, Umathum VG, Bloch W, Rother C, Stahl M, Witte HM, Djudjaj S, Boor P, Steinestel K. Antemortem vs Postmortem Histopathologic and Ultrastructural Findings in Paired Transbronchial Biopsy Specimens and Lung Autopsy Samples From Three Patients With Confirmed SARS-CoV-2. Am J Clin Pathol. 2021;      [DOI] 

Nikolai O, Rohardt C, Tobian F, et al . Anterior nasal versus nasal mid-turbinate sampling for a SARS-CoV-2 antigen-detecting rapid test: does localisation or professional collection matter?. Infect Dis. 2021; 53(12):      [DOI]      [File] 

Popp M, Stegemann M, Riemer M, Metzendorf M, Romero CS, Mikolajewska A, Kranke P, Meybohm P, Skoetz N, Weibel S. Antibiotics for the treatment of COVID‐19. Cochrane Database of Systematic Reviews. 2021; 2021CD015025.      [DOI] 

Aschman T, Schneider J, Greuel S, Meinhardt J, Streit S, Goebel ea. Association Between SARS-CoV-2 Infection and Immune-Mediated Myopathy in Patients Who Have Died. JAMA Neurol. 2021; 78948—960.

Pogarell O, Pröbstl L, Rüb M, Wiegand H, Tüscher O, Lieb K, Wassiliwizky E, Gerlinger G, Heinz A, Falkai P. Auswirkungen der COVID-19-Pandemie auf die Versorgungssituation in psychiatrischen Kliniken in Deutschland. Der Nervenarzt. 2021; 92(6):562—570.      [DOI] 

Klüpfel J, Koros RC, Dehne K, et al . Automated, flow-based chemiluminescence microarray immunoassay for the rapid multiplex detection of IgG antibodies to SARS-CoV-2 in human serum and plasma (CoVRapid CL-MIA). Anal Bioanal Chem. 2021; 413(22):      [DOI] 

Evert K, Dienemann T, Brochhausen C, Lunz D, Lubnow M, Ritzka M, Keil F, Trummer M, Scheiter A, Salzberger B, Stahl D. Autopsy findings after long-term treatment of COVID-19 patients with microbiological correlation. Virchows Arch. 2021; 1-12.      [DOI] 

Arora P, et al . B.1.617.2 enters and fuses lung cells with increased efficiency and evades antibodies induced by infection and vaccination. Cell Reports. 2021; 109825.      [DOI]