Publications in the NUM

Zickler M, Stanelle-Bertram S, Ehret S, et al . Replication of SARS-CoV-2 in adipose tissue determines organ and systemic lipid metabolism in hamsters and humans. Cell Metab. 2022; 341-2.      [DOI] 

Zickler M, Stanelle-Bertram S, Ehret S, Heinrich F, Lange P, Schaumburg B, Kouassi NM, Beck S, Jaeckstein MY, Mann O, Krasemann S, Schroeder M, Jarczak D, Nierhaus A, Kluge S, Peschka M, Schlüter H, Renné T, Pueschel K, Kloetgen A, Scheja L, Ondruschka B, Heeren J, Gabriel G. Replication of SARS-CoV-2 in adipose tissue determines organ and systemic lipid metabolism in hamsters and humans. Cell Metabolism. 2022 Jan.; 34(1):1—2.      [DOI] 

Neidhardt M, Gerlach S, Mieling R, et al . Robotic Tissue Sampling for Safe Post-Mortem Biopsy in Infectious Corpses. IEEE Trans. Med. Robot. Bionics. 2022; 494-105.      [DOI] 

Hammerschmidt S, Thurm C, Bošnjak B, et al . Robust induction of neutralizing antibodies against the SARS‐CoV‐2 Delta variant after homologous Spikevax or heterologous Vaxzevria‐Spikevax vaccination. Eur J Immunol. 2022; 52(2):      [DOI] 

Momsen Reincke S, et al . SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies. Science (New York, N.Y.). 2022;      [DOI] 

Layer E, Hoehl S, Widera M, Bojkova D, Westphal T, Gottschalk R, Boeddinghaus B, Schork J, Ciesek S, Goetsch U. SARS-CoV-2 screening strategies for returning international travellers: Evaluation of a rapid antigen test approach. International Journal of Infectious Diseases. 2022; 118126—131.      [DOI] 

Backhaus I, Hermsen D, Timm J, Boege F, Lübke N, Degode T, Göbels K, Dragano N. SARS-CoV-2 seroprevalence and determinants of infection in young adults: A population-based seroepidemiological study. Public Health. 2022;      [DOI] 

Arora P, et al . SARS-CoV-2 variants C.1.2 and B.1.621 (Mu) partially evade neutralization by antibodies elicited upon infection or vaccination. Cell Reports. 2022; 39110754.      [DOI] 

Steinbeis F, Thibeault C, Doellinger F, Ring RM, Mittermaier M, Ruwwe-Glösenkamp C, Alius F, Knape P, Meyer H, Lippert LJ, Helbig ET, Grund D, Temmesfeld-Wollbrück B, Suttorp N, Sander LE, Kurth F, Penzkofer T, Witzenrath M, Zoller T. Severity of respiratory failure and computed chest tomography in acute COVID-19 correlates with pulmonary function and respiratory symptoms after infection with SARS-CoV-2: An observational longitudinal study over 12 months.. Respiratory medicine. 2022 Jan.;      [DOI] 

Medenwald D, Brunner T, Christiansen H, et al . Shift of radiotherapy use during the first wave of the COVID-19 pandemic? An analysis of German inpatient data. Strahlenther Onkol. 2022; 198(4):334—345.      [DOI] 

Koll C, Hopff S, Meurers T, Lee C, Kohls M, Stellbrink C, Thibeault C, Reinke L, Steinbrecher S, Schreiber S, Stahl D. Statistical biases due to anonymization evaluated in an open clinical dataset from COVID-19 patients. Sci Data. 2022; 9(1):776.      [DOI] 

Mayer M, Zellmer S, Zenk J, et al . Status quo after one year of COVID-19 pandemic in otolaryngological hospital-based departments and private practices in Germany. Eur Arch Otorhinolaryngol. 2022; 279(2):      [DOI] 

Hoven H, Dragano N, Angerer P, Apfelbacher C, Backhaus I, Hoffmann B, Icks A, Wilm S, Fangerau F, Söhner F. Striving for health equality: The importance of social determinants of health and ethical considerations in pandemic preparedness planning. International Journal of Public Health. 2022; 671604542.      [DOI] 

Peter L, et al . Tacrolimus-resistant SARS-CoV-2-specific T cell products to prevent and treat severe COVID-19 in immunosuppressed patients. Molecular therapy. Methods & clinical development. 2022; 2552–73.      [DOI] 

Czypionka T, Iftekhar EN, Prainsack B, Priesemann V, Bauer S, Valdez AC, Cuschieri S, Glaab E, Grill E, Krutzinna J, Lionis C, Machado H, Martins C, Pavlakis GN, Perc M, Petelos E, Pickersgill M, Skupin A, Schernhammer E, Szczurek E, Tsiodras S, Willeit P, Wilmes P. The benefits, costs and feasibility of a low incidence COVID-19 strategy. The Lancet Regional Health-Europe. 2022; 13100294.      [DOI] 

Krasemann S, Haferkamp U, Pfefferle S, et al . The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2. Stem Cell Reports. 2022; 17307-320.      [DOI] 

Tafforeau P, Wagner W, et al . The Bronchial Circulation in COVID-19 Pneumonia. Am J Respir Crit Care Med. 2022; 205121-125.      [DOI] 

Ackermann M, Tafforeau P, Wagner WL, Walsh CL, Werlein C, Kühnel MP, Länger FP, Disney C, Bodey AJ, Bellier A, Verleden SE, Lee PD, Mentzer SJ, Jonigk DD. The Bronchial Circulation in COVID-19 Pneumonia. American Journal of Respiratory and Critical Care Medicine. 2022 Jan.; 205(1):121—125.      [DOI] 

Borusiak P, Mazheika Y, Bauer S, Haberlandt E, Krois I, Fricke C, Simon L, Beschoner P, Jerg-Bretzke L, Geiser F, Hiebel N, Weidner K, Morawa E, Erim Y. The impact of the COVID-19 pandemic on pediatric developmental services: a cross-sectional study on overall burden and mental health status. Arch Public Health. 2022; 80(1):113.

Hannemann J, Erim Y, Morawa E, Jerg-Bretzke L, Beschoner P, Geiser F, Hiebel N, Weidner K, Steudte-Schmiedgen S. The impact of the COVID-19 pandemic on the mental health of medical staff considering the interplay of pandemic burden and psychosocial resources-A rapid systematic review. PLoS One. 2022; 17(2):e0264290.      [DOI] 

Schreiber A, Viemann D, Schöning J, Schloer S, Mecate Zambrano A, Brunotte ea. The MEK1/2-inhibitor ATR-002 efficiently blocks SARS-CoV-2 propagation and alleviates pro-inflammatory cytokine/chemokine responses. Cell Mol Life Sci. 2022; 7965.      [DOI] 

Wratil PR, Stern M, Priller A, et al . Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern. Nat Med. 2022;      [DOI] 

Kamp J, Neubert L, et al . Time-Dependent Molecular Motifs of Pulmonary Fibrogenesis in COVID-19. Int J Mol Sci. 2022; 23      [DOI] 

Kamp JC, Neubert L, Stark H, Werlein C, Fuge J, Haverich A, Tzankov A, Steinestel K, Friemann J, Boor P, Junker K, Hoeper MM, Welte T, Laenger F, Kuehnel MP, Jonigk DD. Time-Dependent Molecular Motifs of Pulmonary Fibrogenesis in COVID-19. International Journal of Molecular Sciences. 2022 Jan.; 23(3):1583.      [DOI] 

Wulff A, Biermann P, von Landesberger T, Baumgartl T, Schmidt C, Schick K, Waldstein P, Zhu Y, Krefting D, Scheithauer S, Marschollek M. Tracing COVID-19 Infection Chains Within Healthcare Institutions - Another Brick in the Wall Against SARS-CoV-2. Studies in health technology and informatics. 2022; 290699—703.      [DOI] 

Schug C, Erim Y, Geiser F, Hiebel N, Beschoner P, Jerg-Bretzke L, Weidner K, Steudte-Schmiedgen S, Borho A, Lieb M, Morawa E. Vaccination willingness against COVID-19 among healthcare workers in Germany: Results from a University Medicine Network survey between November 2020 and January 2021. Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz. 2022 Jan.; 65(1):74—85.      [DOI]      [File] 

Struwe C, Golinski M, Grimm C, Dickel S, Grummich K, Nothacker M, Voigt-Radloff S, Meerpohl J, Moerer O. Vergleich und Bewertung internationaler Leitlinien zur Behandlung schwerer Verläufe von SARS-CoV-2-Infektionen. Dtsch Arztebl Int. 2022; 11923-30.      [DOI] 

Mayer K. Pandemic Disruptions and Transnational Care Relations: Towards Closing the “Care Gap” in International Relations Theories. In: Gephart, W, editors. In the Realm of Corona Normativities II. Verlag Vitorrio Klostermann; 2022.

Reichardt M, Moller Jensen P, Andersen Dahl V, Bjorholm Dahl A, Ackermann M, Shah H, Länger F, Werlein C, Kuehnel MP, Jonigk D, Salditt T. 3D virtual histopathology of cardiac tissue from Covid-19 patients based on phase-contrast X-ray tomography. eLife. 2021 Dec.; 10e71359.      [DOI]      [File] 

Meyer H, Bailis N, Surov A. Can the CT by-product Time to threshold be a prognostic factor in patients with acute pulmonary embolism?. Journal of medical imaging and radiation oncology. 2021 Dec.; 65(7):846-849.      [DOI]      [File] 

Stillfried S, Boor P, PANDEMIcs D. Entwicklung eines kooperativen Obduktionsnetzwerks aus Pathologie, Neuropathologie und Rechtsmedizin. Der Pathologe. 2021 Dec.; 42(2):129—134.      [DOI]      [File] 

Walsh CL, Tafforeau P, Wagner WL, Jafree DJ, Bellier A, Werlein C, Kühnel MP, Boller E, Walker-Samuel S, Robertus JL, Long DA, Jacob J, Marussi S, Brown E, Holroyd N, Jonigk DD, Ackermann M, Lee PD. Imaging intact human organs with local resolution of cellular structures using hierarchical phase-contrast tomography. Nature Methods. 2021 Dec.; 18(12):1532—1541.      [DOI]      [File] 

Wendisch D, Dietrich O, Mari T, Stillfried S, Ibarra IL, Mittermaier M, Mache C, Chua RL, Knoll R, Timm S, Brumhard S, Krammer T, Zauber H, Hiller AL, Pascual-Reguant A, Mothes R, Bülow RD, Schulze J, Leipold AM, Djudjaj S, Erhard F, Geffers R, Pott F, Kazmierski J, Radke J, Pergantis P, Baßler K, Conrad C, Aschenbrenner AC, Sawitzki B, Landthaler M, Wyler E, Horst D, (DeCOI) DCOI, Hippenstiel S, Hocke A, Heppner FL, Uhrig A, Garcia C, Machleidt F, Herold S, Elezkurtaj S, Thibeault C, Witzenrath M, Cochain C, Suttorp N, Drosten C, Goffinet C, Kurth F, Schultze JL, Radbruch H, Ochs M, Eils R, Müller-Redetzky H, Hauser AE, Luecken MD, Theis FJ, Conrad C, Wolff T, Boor P, Selbach M, Saliba A, Sander LE. SARS-CoV-2 infection triggers profibrotic macrophage responses and lung fibrosis. Cell. 2021 Dec.; 184(26):6243—6261.e27.      [DOI] 

Witkowski M, Tizian C, Ferreira-Gomes M, Niemeyer D, Jones TC, Heinrich F, Frischbutter S, Angermair S, Hohnstein T, Mattiola I, Nawrath P, McEwen S, Zocche S, Viviano E, Heinz GA, Maurer M, Kölsch U, Chua RL, Aschman T, Meisel C, Radke J, Sawitzki B, Roehmel J, Allers K, Moos V, Schneider T, Hanitsch L, Mall MA, Conrad C, Radbruch H, Duerr CU, Trapani JA, Marcenaro E, Kallinich T, Corman VM, Kurth F, Sander LE, Drosten C, Treskatsch S, Durek P, Kruglov A, Radbruch A, Mashreghi M, Diefenbach A. Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells. Nature. 2021 Dec.; 600(7888):295—301.      [DOI]      [File] 

Berezowska S, Boor P, Jonigk D, Tischler V. Update Thoraxpathologie 2021 – Bericht der Arbeitsgemeinschaft. Der Pathologe. 2021 Dec.; 42(2):199—202.      [DOI]      [File] 

Smadja DM, Mentzer SJ, Fontenay M, Laffan MA, Ackermann M, Helms J, Jonigk D, Chocron R, Pier GB, Gendron N, Pons S, Diehl J, Margadant C, Guerin C, Huijbers EJM, Philippe A, Chapuis N, Nowak-Sliwinska P, Karagiannidis C, Sanchez O, Kümpers P, Skurnik D, Randi AM, Griffioen AW. COVID-19 is a systemic vascular hemopathy: insight for mechanistic and clinical aspects. Angiogenesis. 2021 Nov.; 24(4):755—788.      [DOI]      [File] 

Lehmann M, Allers K, Heldt C, Meinhardt J, Schmidt F, Rodriguez-Sillke Y, Kunkel D, Schumann M, Böttcher C, Stahl-Hennig C, Elezkurtaj S, Bojarski C, Radbruch H, Corman VM, Schneider T, Loddenkemper C, Moos V, Weidinger C, Kühl AA, Siegmund B. Human small intestinal infection by SARS-CoV-2 is characterized by a mucosal infiltration with activated CD8+ T cells. Mucosal Immunology. 2021 Nov.; 14(6):1381—1392.      [DOI]      [File] 

Ondruschka B, Heinrich F, Lindenmeyer M, Edler C, Möbius D, Czogalla J, Heinemann A, Braun F, Aepfelbacher M, Lütgehetmann M, Huber TB. Multiorgan tropism of SARS-CoV-2 lineage B.1.1.7. International Journal of Legal Medicine. 2021 Nov.; 135(6):2347—2349.      [DOI]      [File] 

Wenzel J, Lampe J, Müller-Fielitz H, Schuster R, Zille M, Müller K, Krohn M, Körbelin J, Zhang L, Özorhan Ü, Neve V, Wagner JUG, Bojkova D, Shumliakivska M, Jiang Y, Fähnrich A, Ott F, Sencio V, Robil C, Pfefferle S, Sauve F, Coêlho CFF, Franz J, Spiecker F, Lembrich B, Binder S, Feller N, König P, Busch H, Collin L, Villaseñor R, Jöhren O, Altmeppen HC, Pasparakis M, Dimmeler S, Cinatl J, Püschel K, Zelic M, Ofengeim D, Stadelmann C, Trottein F, Nogueiras R, Hilgenfeld R, Glatzel M, Prevot V, Schwaninger M. The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells. Nature Neuroscience. 2021 Nov.; 24(11):1522—1533.      [DOI]      [File] 

Gerlach S, Neidhardt M, Weiß T, Laves M, Stapper C, Gromniak M, Kniep I, Möbius D, Heinemann A, Ondruschka B, Schlaefer A. Needle insertion planning for obstacle avoidance in robotic biopsy. Current Directions in Biomedical Engineering. 2021 Oct.; 7(2):779—782.      [DOI]      [File] 

Heinrich F, Nentwich MF, Bibiza-Freiwald E, Nörz D, Roedl K, Christner M, Hoffmann A, Olearo F, Kluge S, Aepfelbacher M, Wichmann D, Lütgehetmann M, Pfefferle S. SARS-CoV-2 Blood RNA Load Predicts Outcome in Critically Ill COVID-19 Patients. Open Forum Infectious Diseases. 2021 Oct.; 8(11):ofab509.      [DOI]      [File] 

Lohner L, Fröb D, Edler C, Schröder AS, Dietz E, Ondruschka B. SARS-CoV-2-assoziierte Todesfälle von erwachsenen Personen bis 50 Jahre. Rechtsmedizin. 2021 Oct.; 31(5):418—426.      [DOI]      [File] 

Klein A, Langenwalder F, Heinrich F, Meißner K, Schröder AS, Püschel K, Ondruschka B, Lütgehetmann M, Heinemann A. SARS-CoV‑2-Zufallsentdeckungen bei Hamburger Todesfällen: ein epidemiologisches Monitoring während des dynamischen Infektionsgeschehens im Frühjahr 2020. Rechtsmedizin. 2021 Oct.; 31(5):427—433.      [DOI]      [File] 

Surov A, Akritidou M, Bach AG, Bailis N, Lerche M, Meyer HJ, Pech M, Wienke A. A New Index for the Prediction of 30-Day Mortality in Patients With Pulmonary Embolism: The Pulmonary Embolism Mortality Score (PEMS). Angiology. 2021 Sep.; 72(8):787-793.      [DOI]      [File] 

Sähn M, Yüksel C, Keil S, Zeisberger MP, Post M, Kleines M, Brokmann JC, Hübel C, Kuhl CK, Isfort P, Schulze-Hagen MF. Accuracy of Chest CT for Differentiating COVID-19 from COVID-19 Mimics. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. 2021 Sep.; 193(9):1081-1091.      [DOI]      [File] 

Ihlow J, Seelhoff A, Corman VM, Gruber AD, Dökel S, Meinhardt J, Radbruch H, Späth-Schwalbe E, Elezkurtaj S, Horst D, Herbst H. COVID-19: a fatal case of acute liver failure associated with SARS-CoV-2 infection in pre-existing liver cirrhosis. BMC Infectious Diseases. 2021 Sep.; 21(1):901.      [DOI]      [File] 

Metzendorf M. Das Cochrane COVID-19 Studienregister – eine studienbasierte, strukturierte Datenbank zur effizienten Identifizierung wissenschaftlicher Evidenz. GMS Med Bibl Inf. 2021 Sep.; 21(1-2):Doc09.      [DOI] 

Fitzek A, Schädler J, Dietz E, Ron A, Gerling M, Kammal A, Lohner L, Falck C, Möbius D, Goebels H, Gerberding A, Schröder A, Sperhake J, Klein A, Fröb D, Mushumba H, Wilmes S, Kniep I, Heinrich F, Langenwalder F, Meißner K, Lange P, Zapf A, Püschel K, Heinemann A, Glatzel M, Matschke J, Lütgehetmann M, Steurer S, Thorns C, Edler C, Ondruschka B. Prospective postmortem evaluation of 735 consecutive SARS-CoV-2-associated death cases. Sci Rep. 2021 Sep.; 11(1):19342.      [DOI] 

Fitzek A, Schädler J, Dietz E, Ron A, Gerling M, Kammal AL, Lohner L, Falck C, Möbius D, Goebels H, Gerberding A, Schröder AS, Sperhake J, Klein A, Fröb D, Mushumba H, Wilmes S, Anders S, Kniep I, Heinrich F, Langenwalder F, Meißner K, Lange P, Zapf A, Püschel K, Heinemann A, Glatzel M, Matschke J, Aepfelbacher M, Lütgehetmann M, Steurer S, Thorns C, Edler C, Ondruschka B. Prospective postmortem evaluation of 735 consecutive SARS-CoV-2-associated death cases. Scientific Reports. 2021 Sep.; 11(1):19342.      [DOI]      [File] 

Schröder AS, Edler C, Ondruschka B, Püschel K, Schädler J, Heinemann A, Heinrich F, Lütgehetmann M, Pfefferle S, Aepfelbacher M, Fitzek A, Sperhake J. The handling of SARS-CoV-2 associated deaths - infectivity of the body. Forensic Science, Medicine and Pathology. 2021 Sep.; 17(3):411—418.      [DOI]      [File]