Publications in the NUM

Kades K, Scherer J, Scholtyssek J, Penzkofer T, Nolden M, Maier-Hein K. Efficient DICOM Image Tagging and Cohort Curation Within Kaapana. Informatik aktuell. 2022; 279-284.      [DOI]      [File] 

Pietzner M, Chua RL, Wheeler E, Jechow K, Radbruch H, Trump ea. ELF5 is a respiratory epithelial cell-specific risk gene for severe COVID-19. medRxiv. 2022;      [DOI] 

Hopff S, Tilch K, Kraus M, Lorenz-Depiereux L, Anton G, Appel K, Bahmer T, Bartschke A, Bellinghausen C, Bernemann I, Stahl D. Ethical and coordinative challenges in setting up a national cohort study exemplified by the German National Pandemic Cohort Network (NAPKON). Abstract ECCMID 2022. 2022;

Antoniou K, Vasarmidi E, Russell A, Crestani B, Delcroix M, Dinh-Xuan A, Poletti V, Sverzellati N, Vitacca M, Witzenrath M, Tonia T, Spanevello A. European Respiratory Society statement on long COVID follow-up. Eur Respir J. 2022; 60(2):2102174.      [DOI] 

Krüger L, Klein J, Tobian F, Stahl D. Evaluation of accuracy, exclusivity, limit-of-detection and ease-of-use of LumiraDx™: An antigen-detecting point-of-care device for SARS-CoV-2. Infection. 2022; 50      [DOI]      [File] 

Hoffmann M, et al . Evidence for an ACE2-Independent Entry Pathway That Can Protect from Neutralization by an Antibody Used for COVID-19 Therapy. mBio. 2022;      [DOI] 

Meyer H, Wienke A, Surov A. Extrapulmonary CT Findings Predict In-Hospital Mortality in COVID-19. A Systematic Review and Meta-Analysis. Academic radiology. 2022 Jan.; 29(1):17-30.      [DOI]      [File] 

Menger J, Apostolidou S, Edler C, Kniep I, Kobbe R, Singer D, Sperhake J. Fatal outcome of SARS-CoV-2 infection (B1.1.7) in a 4-year-old child. International Journal of Legal Medicine. 2022 Jan.; 136(1):189—192.      [DOI]      [File] 

Woon S, Sheppard M, et al . First Identified Case of Fatal Fulminant Necrotizing Eosinophilic Myocarditis Following the Initial Dose of the Pfizer-BioNTech mRNA COVID-19 Vaccine (BNT162b2, Comirnaty): an Extremely Rare Idiosyncratic Hypersensitivity Reaction. J Clin Immunol. 2022;      [DOI] 

Von Stillfried S, Bülow R, Röhrig R, Boor P, Collaborators D. First report from the German COVID-19 autopsy registry. The Lancet Regional Health - Europe. 2022; 100330.      [DOI] 

Steinbeis F, Knape P, Mittermaier M, Helbig E, Tober-Lau P, Thibeault C, Lippert L, Xiang W, Müller-Plathe M, Steinbrecher S, Stahl D. Functional limitations 12 months after SARS-CoV-2 infection correlate with initial disease severity: An observational study of cardiopulmonary exercise capacity testing in COVID-19 convalescents. Respir Med. 2022; 202106968.      [DOI] 

Kühnapfel A, Horn K, Klotz U, Kiehntopf M, Rosolowski M, Loeffler M, Suttorp N, Witzenrath M, Scholz M. Genetic Regulation of Cytokine Response in Patients with Acute Community-Acquired Pneumonia. Genes (Basel). 2022; 13(1):111.      [DOI] 

Dannebaum R, Suwalski P, Asgharian H, Du ZG, Lin H, Weiner J, Holtgrewe M, Thibeault C, Müller M, Wang X, Stahl D. Highly multiplexed immune repertoire sequencing links multiple lymphocyte classes with severity of response to COVID-19. EClinicalMedicine. 2022; 48101438.      [DOI] 

Hönzke K, Obermayer B, Mache C, Fathykova D, Kessler M, Dökel S, Wyler E, Baumgardt M, Löwa A, Hoffmann K, Stahl D. Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages. Eur Respir J. 2022; 60(6):2102725.      [DOI] 

Hönzke K, Obermayer B, Mache C, Fathykova D, Kessler M, Dökel ea. Human lungs show limited permissiveness for SARS-CoV-2 due to scarce ACE2 levels but virus-induced expansion of inflammatory macrophages. Eur Respir J. 2022; 60(6):2102725.      [DOI] 

Kardas H, Thormann M, Bär C, Omari J, Wienke A, Pech M, Surov A. Impact of Pectoral Muscle Values on Clinical Outcomes in Patients With Severe Covid-19 Disease. In vivo (Athens, Greece). 2022; 36(1):375-380.      [DOI]      [File] 

Bernatz S, Afat S, Othman AE, Nikolaou K, Sieren M, Sähn M, Pinto Dos Santos D, Penzkofer T, Bucher AM, Hamm B, Vogl TJ, Bodelle B. Impact of the COVID-19 Pandemic on Radiology in Inpatient and Outpatient Care in Germany: A Nationwide Survey Regarding the First and Second Wave. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. 2022 Jan.; 194(1):70-82.      [DOI]      [File] 

Sedlmayr B, Sedlmayr M, Schüttler C, et al . Improving collaborative COVID-19 research of University Hospitals in Germany: Formative usability evaluation of the CODEX-Feasibility Portal. Appl Clin Inform. 2022; 13400—409.      [DOI] 

Wratil PR, Schmacke NA, Osterman A, et al . In-depth profiling of COVID-19 risk factors and preventive measures in healthcare workers. Infection. 2022; 50      [DOI] 

Dragano N, Reuter M, Peters A, Engels M, Schmidt B, Greiser K, Bohn B, Riedel-Heller S, Karch A, Mikolajczyk R, Krause G, Lang O, Panreck L, Rietschel M, Brenner H, Fischer B, Franzke C, Gastell S, Holleczek B, Jöckel K, Kaaks R, Keil T, Kluttig A, Kuß O, Legath N, Leitzmann M, Lieb W, Meinke-Franze C, Michels K, Obi N, Pischon T, Feinkohl I, Rospleszcz S, Schikowski T, Schulze M, Stang A, Völzke H, Willlich S, Wirkner K, Zeeb H, Berger K. Increase in mental disorders during the COVID-19 pandemic - the role of occupational and financial strains. An analysis of the German National Cohort (NAKO) Study. Deutsches Ärzteblatt International. 2022; 119179–187.      [DOI] 

Bludau A, Heinemann S, Mardiko A, Kaba H, Leha A, von Maltzahn N, Mutters N, Leistner R, Mattner F, Scheithauer S. Infection control strategies for patients and accompanying persons during the COVID-19 pandemic in German hospitals: a cross-sectional study in March-April 2021. The Journal of hospital infection. 2022; 12528—36.      [DOI] 

Bludau A, Heinemann S, Mardiko AA, Kaba HEJ, Leha A, Maltzahn N, Mutters NT, Leistner R, Mattner F, Scheithauer S. Infection control strategies for patients and accompanying persons during the COVID-19 pandemic in German hospitals: a cross-sectional study in March–April 2021. Journal of Hospital Infection. 2022;      [DOI]      [File] 

Houwaart T, Belhaj S, Tawalbeh E, Nagels D, Fröhlich Y, Finzer P, Ciruela P, Sabrià A, Herrero M, Andrés C, Antón A, Benmoumene A, Asskali D, Haidar H, von Dahlen J, Nicolai J, Stiller M, Blum J, Lange C, Adelmann C, Schroer B, Osmers U, Grice C, Kirfel P, Jomaa H, Strelow D, Hülse L, Pigulla M, Kreuzer P, Tyshaieva A, Weber J, Wienemann T, Kohns Vasconcelos M, Hoffmann K, Lübke N, Hauka S, Andree M, Scholz C, Jazmati N, Göbels K, Zotz R, Pfeffer K, Timm J, Ehlkes L, Walker A, Dilthey A, German COVID-19 OMICS Initiative (DeCOI) . Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021. Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin. 2022; 27(43):      [DOI] 

Torsten H, Samir B, Emran T, Dirk N, Yara F, Patrick F, Pilar C, Aurora S, Mercè H, Cristina A, Andrés A, Assia B, Dounia A, Hussein H, Janina , Jessica N, Mygg S, Jacqueline B, Christian L, Carla A, Britta S, Ute O, Christiane G, P. KP, Hassan J, Daniel S, Lisanna H, Moritz P, Pascal K, Alona T, Jonas W, Tobias W, Malte KV, Katrin H, Nadine L, Sandra H, Marcel A, Juergen SC, Nathalie J, Klaus G, Rainer Z, Klaus P, Joerg T, Lutz E, Andreas W, T. DA, (DeCOI) GCOI. Integrated genomic surveillance enables tracing of person-to-person SARS-CoV-2 transmission chains during community transmission and reveals extensive onward transmission of travel-imported infections, Germany, June to July 2021.. Eurosurveillance. 2022;      [DOI]      [File] 

Müller A, Haneke H, Kirchberger V, Mastella G, Dommasch M, Merle U, Heinze O, Siegmann A, Spinner C, Buiatti A, Laugwitz K, Schmidt G, Martens E. Integration of mobile sensors in a telemedicine hospital system: Remote-monitoring in COVID-19 patients. Journal of Public Health. 2022; 30(1):93—97.      [DOI] 

Kantauskaite M, et al . Intensity of mycophenolate mofetil treatment is associated with an impaired immune response to SARS-CoV-2 vaccination in kidney transplant recipients. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2022; 22634–639.      [DOI] 

Oorschot , Stahl D. Interaktive Homepage für Trauernde in Pandemiezeiten. Schmerz, Nervenarzt, Forum DKG, Urologe, Onkologe. 2022;

Dönges P, Wagner J, Contreras S, Iftekhar EN, Bauer S, Mohr SB, Dehning J, Valdez AC, Kretzschmar M, Mäs M, Nagel K, Priesemann V. Interplay Between Risk Perception, Behavior, and COVID-19 Spread. Frontiers in Physics. 2022; 10842180.      [DOI] 

Stillfried S, Bülow R, Röhrig R, Meybohm P, Boor P. Intracranial hemorrhage in COVID-19 patients during extracorporeal membrane oxygenation for acute respiratory failure: a nationwide register study report. Critical care (London, England). 2022; 2683.      [DOI] 

Pauli B, Strupp J, Schloesser K, Stahl D. It’s like standing in front of a prison fence – Dying during the SARS-CoV2 pandemic: A qualitative study of bereaved relatives’ experiences. Palliative Medicine. 2022;      [DOI] 

Krishnaratne S, Littlecott H, Sell K, Burns J, Rabe JE, Stratil JM, Litwin T, Kreutz C, Coenen M, Geffert K, Boger AH, Movsisyan A, Kratzer S, Klinger C, Wabnitz K, Strahwald B, Verboom B, Rehfuess E, Biallas RL, Jung-Sievers C, Voss S, Pfadenhauer LM. Measures implemented in the school setting to contain the COVID-19 pandemic: a rapid review. Cochrane Database of Systematic Reviews. 2022; 2022CD015029.      [DOI] 

Ackermann M, Jonigk DD. Microvascular placental alterations in maternal COVID-19. American Journal of Obstetrics and Gynecology. 2022 Jan.; 226(1):135—136.      [DOI] 

Schwartz J, Reuters MC, Schallenburger M, Meier S, Roch C, Werner L, Oorschot B, Neukirchen M. Modelle guter Praxis: Alleine sterben ist ethisch nicht vertretbar. Praxis Palliative Care. 2022; 5429-36.

Wanner N, Andrieux G, Badia-i-Mompel P, et al . Molecular consequences of SARS-CoV-2 liver tropism. Nat Metab. 2022; 4310-319.      [DOI] 

Gruell H, et al . mRNA booster immunization elicits potent neutralizing serum activity against the SARS-CoV-2 Omicron variant. Nature Medicine. 2022;      [DOI] 

Liu Z, et al . Multi-Omics Integration Reveals Only Minor Long-Term Molecular and Functional Sequelae in Immune Cells of Individuals Recovered From COVID-19. Frontiers in immunology. 2022; 13838132.      [DOI] 

Bausewein C, Hodiamont F, Berges N, Ullrich A, Gerlach C, Oechsle K, Pauli B, Weber J, Stiel S, Schneider N, Stahl D. National strategy for palliative care of severely ill and dying people and their relatives in pandemics (PallPan) in Germany - study protocol of a mixed-methods project. BMC palliative care. 2022; 21(1):10.      [DOI] 

Heinrich F, Roedl K, Jarczak D, et al . New Insights in the Occurrence of Venous Thromboembolism in Critically Ill Patients with COVID-19—A Large Postmortem and Clinical Analysis. Viruses. 2022; 14811.      [DOI] 

Arora P, et al . No evidence for increased cell entry or antibody evasion by Delta sublineage AY.4.2. Cellular & Molecular Immunology. 2022;      [DOI] 

Ercanoglu MS, et al . No substantial preexisting B cell immunity against SARS-CoV-2 in healthy adults. iScience. 2022; 25103951.      [DOI] 

Zellmer S, Bachmann E, Muzalyova A, et al . One year of the COVID-19 pandemic in dental medical facilities in Germany: A questionnaire-based analysis. Int J Environ Res Public Health. 2022; 19(1):      [DOI] 

Jonigk D, Werlein C, et al . Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies?. Virchows Arch. 2022;      [DOI] 

Oorschot , Stahl D. PallPan Richtig handeln in der Betreuung Schwerkranker und Sterbender in Pandemiezeiten. Der Ophthalmologe. 2022;

Ebler J, Ebert P, Clarke W, Rausch T, Audano P, Houwaart T, Mao Y, Korbel J, Eichler E, Zody M, Dilthey A, Marschall T. Pangenome-based genome inference allows efficient and accurate genotyping across a wide spectrum of variant classes. Nature genetics. 2022; 54(4):518—525.      [DOI] 

Ebler J, Ebert P, Clarke WE, Rausch T, Audano PA, Houwaart T, Mao Y, Korbel JO, Eichler EE, Zody MC, Dilthey AT, Marschall T. Pangenome-based genome inference allows efficient and accurate genotyping across a wide spectrum of variant classes. Nature Genetics. 2022;      [DOI]      [File] 

Heinrich F, Schröder A, Gerberding A, et al . Postmortem Antigen-Detecting Rapid Diagnostic Tests to Predict Infectivity of SARS-CoV-2-Associated Deaths. Emerg Infect Dis. 2022; 28244-247.      [DOI] 

Heinrich F, Schröder AS, Gerberding A, Gerling M, Langenwalder F, Lange P, Heinemann A, Bibiza-Freiwald E, Nörz DS, Aepfelbacher M, Pfefferle S, Ondruschka B, Lütgehetmann M. Postmortem Antigen-Detecting Rapid Diagnostic Tests to Predict Infectivity of SARS-CoV-2-Associated Deaths. Emerging Infectious Diseases. 2022 Jan.; 28(1):244—247.      [DOI] 

Schwarz T, et al . Preserved T cell responses to SARS-CoV-2 in anti-CD20 treated multiple sclerosis. Multiple Sclerosis Journal. 2022;      [DOI] 

Gorji H, Stauffer N, Lunati I, et al . Projection of healthcare demand in Germany and Switzerland urged by omicron wave (January-March 2022). MedRxiv. 2022;      [DOI] 

Dächert C, Muenchhoff M, Graf A, et al . Rapid and sensitive identification of omicron by variant-specific PCR and nanopore sequencing: paradigm for diagnostics of emerging SARS-CoV-2 variants. Med Microbiol Immunol. 2022; 211(1):      [DOI]      [File]