Publications in the NUM

Here you will find a list of publications that were written in connection with the Network of University Medicine in the first and second funding phases.

Shi Y, Strobl R, Apfelbacher C, Bahmer T, Geisler R, Heuschmann P, Horn A, Hoven H, Keil T, Krawczak M, Krist L, Lemhöfer C, Lieb W, Lorenz-Depiereux B, Mikolajczyk R, Montellano FA, Reese JP, Schreiber S, Skoetz N, Störk S, Vehreschild JJ, Witzenrath M, Grill E, NAPKON Study Group . Persistent symptoms and risk factors predicting prolonged time to symptom-free after SARS‑CoV‑2 infection: an analysis of the baseline examination of the German COVIDOM/NAPKON-POP cohort. Infection. 2023 May; 51(6):1679–1694.      [DOI]  [Pubmed] 
Mieling R, Neidhardt M, Latus S, Stapper C, Gerlach S, Kniep I, Heinemann A, Ondruschka B, Schlaefer A. Collaborative Robotic Biopsy with Trajectory Guidance and Needle Tip Force Feedback. In: 2023 May. p. 6893—6900.      [DOI] 
Tayebi Arasteh S, Isfort P, Saehn M, Mueller-Franzes G, Khader F, Kather JN, Kuhl C, Nebelung S, Truhn D. Collaborative training of medical artificial intelligence models with non-uniform labels.. Scientific reports. 2023 Apr.;      [DOI] 
Thibeault C, Bardtke L, Vanshylla K, Cristanziano V, Eberhardt KA, Stubbemann P, Hillus D, Tober-Lau P, Mukherjee P, Münn F, Lippert LJ, Helbig ET, Lingscheid T, Steinbeis F, Mittermaier M, Witzenrath M, Zoller T, Group P, Klein F, Sander LE, Kurth F. Short- and long-term T cell and antibody responses following dexamethasone treatment in COVID-19. JCI Insight. 2023 Apr.; 8(8):      [DOI]  [Pubmed] 
Heinrich F, Huter T, Mertens S, Lange P, Vering J, Heinemann A, Nörz DS, Hoffmann A, Ondruschka B, Krasemann S, Lütgehetmann M. New Postmortem Perspective on Emerging SARS-CoV-2 Variants of Concern, Germany. Emerging Infectious Diseases. 2023 Mar.; 29(3):652—656.      [DOI] 
Lücke J, Nawrocki M, Schnell J, Meins N, Heinrich F, Zhang T, Bertram F, Sabihi M, Böttcher M, Blankenburg T, Pfaff M, Notz S, Kempski J, Reeh M, Wolter S, Mann O, Izbicki JR, Lütgehetmann M, Duprée A, Giannou AD, Ondruschka B, Huber S. TNFα aggravates detrimental effects of SARS-CoV-2 infection in the liver. Frontiers in Immunology. 2023 Mar.; 141151937.      [DOI] 
Surov A, Thormann M, Kardas H, Hinnerichs M, Omari J, Cingöz E, Cingöz M, Dursun M, Kormaz İ, Orhan Ç, Yıldız Ö, Hocaoglu E, Inci E, Önder H, Erk H, Chousein O, Sasani H, Gönen KA, Pech M, Wienke A. Visceral to subcutaneous fat ratio predicts short-term mortality in patients with Covid 19. A multicenter study.. The British journal of radiology. 2023 Mar.;      [DOI] 
Mothes R, Pascual-Reguant A, Koehler R, Liebeskind J, Liebheit A, Bauherr S, Philipsen L, Dittmayer C, Laue M, Von Manitius R, Elezkurtaj S, Durek P, Heinrich F, Heinz GA, Guerra GM, Obermayer B, Meinhardt J, Ihlow J, Radke J, Heppner FL, Enghard P, Stockmann H, Aschman T, Schneider J, Corman V, Sander LE, Mashreghi M, Conrad T, Hocke A, Niesner RA, Radbruch H, Hauser AE. Distinct tissue niches direct lung immunopathology via CCL18 and CCL21 in severe COVID-19. Nature Communications. 2023 Feb.; 14(1):791.      [DOI]      [File] 
Kottlors J, Fervers P, Geißen S, Gertz RJ, Bremm J, Rinneburger M, Weisthoff M, Shahzad R, Maintz D, Persigehl T. Morphological appearance of the B.1.1.7 mutation of the novel coronavirus 2 (SARS-CoV-2) in chest CT.. Quantitative imaging in medicine and surgery. 2023 Feb.;      [DOI] 
Winkelmann S, Korth A, Voss B, Nasr MA, Behrend N, Pudszuhn A, Hofmann VM, Schendzielorz P, Maetzler C, Hermes A, Borzikowsky C, Bahmer T, Lieb W, Schreiber S, Störk S, Montellano FA, Witzenrath M, Keil T, Krawczak M, Laudien M, On Behalf Of The Napkon Study Group . Persisting chemosensory dysfunction in COVID-19 - a cross-sectional population-based survey. Rhinology. 2023 Feb.; 61(1):12—23.      [DOI] 
TODO
Silber A, Platte S, Kumar A, Arora S, Kadioglu D, Schmidt M, Storf H, Chiocchetti AG, Freitag CM. Admission rates and clinical profiles of children and youth with eating disorders treated as inpatients before and during the COVID-19 pandemic in a German university hospital.. Frontiers in public health. 2023;      [DOI] 
Salzberger B, Mellmann A, Bludau A, Ciesek S, Corman V, Dilthey A, Donker T, Eckmanns T, Egelkamp R, Gaterman SG, Grundmann H, Haecker G, Kaase M, Lange B, Mielke M, Pletz MW, Semmler T, Thuermer A, Wieler LH, Wolff T, Widmer AF, Scheithauer S. An appeal for strengthening genomic pathogen surveillance to improve pandemic preparedness and infection prevention: the German perspective. Infection. 2023;      [DOI]      [File] 
Hellwig D, Hellwig NC, Boehner S, Fuchs T, Fischer R, Schmidt D. Artificial intelligence and deep learning for advancing PET image reconstruction: State-of-the-art and future directions. Nuklearmedizin. 2023; 62(6):334—342.      [DOI]  [Weblink] 
Tayebi Arasteh S, Romanowicz J, Pace DF, Golland P, Powell AJ, Maier AK, Truhn D, Brosch T, Weese J, Lotfinia M, Geest RJ, Moghari MH. Automated segmentation of 3D cine cardiovascular magnetic resonance imaging. Frontiers in cardiovascular medicine. 2023; 101167500.      [DOI]      [File] 
Yusuf KO, Schoneberg A, Hanß S, Wiesenfeldt M, Stecher M, Mitrov L, Hopff SM, Steinbrecher S, Kurth F, Bahmer T, Schreiber S, Pape D, Hofmann A, Kohls M, Störk S, Stubbe HC, Tebbe JJ, Hellmuth JC, Erber J, Krist L, Rieg S, Pilgram L, Vehreschild JJ, Reese J, Krefting D. Consistency as a Data Quality Measure for German Corona Consensus Items Mapped from National Pandemic Cohort Network Data Collections. Methods Inf Med. 2023 Jan.; 62(S 01):e47—e56.      [DOI] 
Lebedin M, García CV, Spatt L, Ratswohl C, Thibeault C, Ostendorf L, Paul F, Sander LE, Kurth F, Rosa K. Discriminating promiscuous from target-specific autoantibodies in COVID-19. European Journal of Immunology. 2023; 53(5):2250210.      [DOI]  [Pubmed]      [File] 
Fuchs T, Kaiser L, Müller D, Papp L, Fischer R, Tran-Gia J. Enhancing interoperability and harmonisation of nuclear medicine image data and associated clinical data. Nuklearmedizin. 2023; 62(6):389-398.      [DOI]  [Weblink] 
Scheithauer S, Dilthey A, Bludau A, Ciesek S, Corman V, Donker T, Eckmanns T, Egelkamp R, Grundmann H, Haecker G, Kaase M, Lange B, Mellmann A, Mielke M, Pletz M, Salzberger B, Thuermer A, Widmer A, Wieler LH, Wolff T, Gatermann S, Semmler T. Etablierung der Genomischen Erreger-Surveillance zur Stärkung des Pandemie- und Infektionsschutzes in Deutschland. [Establishment of genomic pathogen surveillance to strengthen pandemic preparedness and infection prevention in Germany].. Bundesgesundheitsblatt -Gesundheitsforschung - Gesundheitsschutz. 2023;      [DOI]      [File] 
Hoffmann M, Wong L, Arora P, Zhang L, Rocha C, Odle A, Nehlmeier I, Kempf A, Richter A, Halwe N, Schön J, Ulrich L, Hoffmann D, Beer M, Drosten C, Perlman S, Pöhlmann S. Omicron subvariant BA.5 efficiently infects lung cells. Nature communications. 2023; 14(1):3500.      [DOI] 
Hoffmann M, Wong LR, Arora P, Zhang L, Rocha C, Odle A, Nehlmeier I, Kempf A, Richter A, Halwe NJ, Schoen J, Ulrich L, Hoffmann D, Beer M, Drosten C, Perlman S, Poehlmann S. Omicron subvariant BA.5 efficiently infects lung cells. Nature Communications. 2023;      [DOI]      [File] 
Fervers P, Fervers F, Rinneburger M, Weisthoff M, Kottlors J, Reimer R, Zopfs D, Celik E, Maintz D, Große-Hokamp N, Persigehl T. Physiological iodine uptake of the spine's bone marrow in dual-energy computed tomography - using artificial intelligence to define reference values based on 678 CT examinations of 189 individuals.. Frontiers in endocrinology. 2023;      [DOI] 
Surov A, Kardas H, Besutti G, Pellegrini M, Ottone M, Onur MR, Atak F, Erdemir AG, Hocaoglu E, Yıldız Ö, Inci E, Cingöz E, Cingöz M, Dursun M, Korkmaz İ, Orhan Ç, Strobel A, Wienke A, Pech M. Prognostic Role of the Pectoralis Musculature in Patients with COVID-19. A Multicenter Study.. Academic radiology. 2023 Jan.;      [DOI] 
Miederer I, Rogasch JMM, Fischer R, Fuchs T, Lapa C, Lohmann P, Shi K, Tran-Gia J, Wendler T, Hellwig D. The Medical Informatics Initiative and the Network University Medicine - Perspectives for Nuclear Medicine. Nuklearmedizin. 2023; 62(5):276—283.      [DOI]  [Weblink] 
Thiam P, Lausser L, Kloth C, Blaich D, Liebold A, Beer M, Kestler HA. Unsupervised domain adaptation for the detection of cardiomegaly in cross-domain chest X-ray images.. Frontiers in artificial intelligence. 2023;      [DOI] 
Berens M, Bludau A, Fenz D, Hoffmann J, Lang C, Schmitt J, Hoffmann W, Scheithauer S. Leadership is replaced by participation in Pandemic Preparedness: A rapid review of the existing evidence on recommended approaches in crises.. In: 7th International Conference on Prevention & Infection Control (ICPIC), Geneva, Switzerland.. 2023.      [DOI]      [File] 
Scheithauer S, Bludau A, Heinemann S, Anton M, Knolle P. COVID-19-Impfstrategien für Beschäftigte deutscher Kliniken: Ergebnisse einer Befragung von Leitungen der (Krankenhaus‑)Hygiene im Rahmen des B-FAST-Projektes [COVID-19 vaccination strategy for employees of German hospitals: results of a survey of infection control practitioners within the B-FAST project]. Bundesgesundheitsbl. 2022 Dec.; 651299–1306.      [DOI]      [File] 
Almubarak H, Elsayed S, Mazzacane F, Schlunk F, Cao H, Vu LH, Vogt E, Dell Orco A, Desser D, Böhmer MFH, Akkurt BH, Sporns PB, Penzkofer T, Hanning U, Morotti A, Nawabi J. Diagnostic Accuracy and Reliability of Noncontrast Computed Tomography Markers for Acute Hematoma Expansion among Radiologists.. Tomography (Ann Arbor, Mich.). 2022 Dec.;      [DOI] 
Fervers P, Fervers F, Jaiswal A, Rinneburger M, Weisthoff M, Pollmann-Schweckhorst P, Kottlors J, Carolus H, Lennartz S, Maintz D, Shahzad R, Persigehl T. Assessment of COVID-19 lung involvement on computed tomography by deep-learning-, threshold-, and human reader-based approaches-an international, multi-center comparative study.. Quantitative imaging in medicine and surgery. 2022 Nov.;      [DOI] 
González C, Gotkowski K, Fuchs M, Bucher A, Dadras A, Fischbach R, Kaltenborn IJ, Mukhopadhyay A. Distance-based detection of out-of-distribution silent failures for Covid-19 lung lesion segmentation. Medical image analysis. 2022 Nov.; 82102596.      [DOI]      [File] 
Hartung TJ, Neumann C, Bahmer T, Chaplinskaya-Sobol I, Endres M, Geritz J, Haeusler KG, Heuschmann PU, Hildesheim H, Hinz A, Hopff S, Horn A, Krawczak M, Krist L, Kudelka J, Lieb W, Maetzler C, Mehnert-Theuerkauf A, Montellano FA, Morbach C, Schmidt S, Schreiber S, Steigerwald F, Störk S, Maetzler W, Finke C. Fatigue and cognitive impairment after COVID-19: A prospective multicentre study. EClinicalMedicine. 2022 Nov.; 53(101651):101651.      [DOI]  [Pubmed] 
Werlein C, Ackermann M, Stark H, Shah HR, Tzankov A, Haslbauer JD, Stillfried S, Bülow RD, El-Armouche A, Kuenzel S, Robertus JL, Reichardt M, Haverich A, Höfer A, Neubert L, Plucinski E, Braubach P, Verleden S, Salditt T, Marx N, Welte T, Bauersachs J, Kreipe H, Mentzer SJ, Boor P, Black SM, Länger F, Kuehnel M, Jonigk D. Inflammation and vascular remodeling in COVID-19 hearts. Angiogenesis. 2022 Nov.; 26(2):233—248.      [DOI]      [File] 
Gaede K, Heidemann J, Goebels H, Heinemann A, Püschel K, Ondruschka B. Pandemic Preparedness bei der Obduktion? Potentiale und Grenzen des IfSG. Medizinrecht. 2022 Nov.; 40(11):892—901.      [DOI]      [File] 
Yüksel C, Sähn M, Kleines M, Brokmann JC, Kuhl CK, Truhn D, Ritter A, Isfort P, Schulze-Hagen MF. Possible Alterations of Imaging Patterns in Computed Tomography for Delta-VOC of SARS-CoV-2. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. 2022 Nov.; 194(11):1229-1241.      [DOI]      [File] 
Lemhöfer C, Appel KS, Häuser W, Hettich N, Kohls M, Polidori MC. Post-COVID: Alles eine Frage der Definition?. Dtsch Med Wochenschr. 2022 Oct.; 147(21):1391—1397.
Voigtlaender M, Edler C, Gerling M, Schädler J, Ondruschka B, Schröder AS, Sperhake J, Ehrhardt S, Wang L, Haddad M, Kiencke V, Renné T, Roedl K, Kluge S, Wichmann D, Länger F. Thromboembolic events in deceased patients with proven SARS-CoV-2 infection: Frequency, characteristics and risk factors. Thrombosis Research. 2022 Oct.; 218171—176.      [DOI]      [File] 
Krasemann S, Dittmayer C, Stillfried S, Meinhardt J, Heinrich F, Hartmann K, Pfefferle S, Thies E, Manitius R, Aschman TAD, Radke J, Osterloh A, Schmid S, Buhl E, Ihlow J, Dubois F, Arnhold V, Elezkurtaj S, Horst D, Hocke A, Timm S, Bachmann S, Corman V, Goebel H, Matschke J, Stanelle-Bertram S, Gabriel G, Seilhean D, Ondruschka B, Ochs M, Stenzel W, Heppner FL, Boor P, Radbruch H, Laue M, Glatzel M. Assessing and improving the validity of COVID-19 autopsy studies - A multicentre approach to establish essential standards for immunohistochemical and ultrastructural analyses. EBioMedicine. 2022 Sep.; 83104193.      [DOI] 
Casagrande M, Fitzek A, Spitzer M, Püschel K, Glatzel M, Krasemann S, Aepfelbacher M, Nörz D, Lütgehetmann M, Pfefferle S, Schultheiss M. Detection of SARS-CoV-2 genomic and subgenomic RNA in retina and optic nerve of patients with COVID-19. The British Journal of Ophthalmology. 2022 Sep.; 106(9):1313—1317.      [DOI] 
Bahmer T, Borzikowsky C, Lieb W, Horn A, Krist L, Fricke J, Scheibenbogen C, Rabe KF, Maetzler W, Maetzler C, Laudien M, Frank D, Ballhausen S, Hermes A, Miljukov O, Haeusler KG, Mokhtari NEE, Witzenrath M, Vehreschild JJ, Krefting D, Pape D, Montellano FA, Kohls M, Morbach C, Störk S, Reese J, Keil T, Heuschmann P, Krawczak M, Schreiber S, group N. Severity, predictors and clinical correlates of Post-COVID syndrome (PCS) in Germany: A prospective, multi-centre, population-based cohort study. EClinicalMedicine. 2022 Sep.; 51(101549):101549.      [DOI]  [Pubmed] 
Paparoupa M, Schröder AS, Braunsteiner J, Addo MM, Lütgehetmann M, Roedl K, Kluge S, Ondruschka B, Wichmann D. The Effects of SARS-CoV-2 Virus Type and of Vaccination Status on Causes of Death Over the Course of the COVID-19 Pandemic.. Deutsches Ärzteblatt International. 2022 Sep.; 119(35-36):607—608.      [DOI]      [File] 
Thormann M, Lerach T, Gottschling S, Omari J, Pech M, Surov A. [Radiology residency training during the COVID-19 pandemic : Conception and evaluation of a three-phase online-based teaching concept]. Radiologie (Heidelberg, Germany). 2022 Aug.; 62(8):692-700.      [DOI]      [File] 
Schmidt M, Gebauer S, Bartholmes A, Kadioglu D, Kleesiek J, Hamm B, Vogl TJ, Penzkofer T, Bucher AM, Storf H. CODEX Meets RACOON - A Concept for Collaborative Documentation of Clinical and Radiological COVID-19 Data. Studies in health technology and informatics. 2022 Aug.; 29658-65.      [DOI]      [File] 
Meyer T, Stubbemann P, Thibeault C, Staudacher O, Niemeyer D, Jansen J, Mühlemann B, Doehn J, Tabeling C, Nusshag C, Hirzel C, Sanchez DS, Nieters A, Lother A, Duerschmied D, Schallner N, Lieberum J, August D, Rieg S, Falcone V, Hengel H, Kölsch U, Unterwalder N, Hübner R, Jones TC, Suttorp N, Drosten C, Warnatz K, Spinetti T, Schefold JC, Dörner T, Sander LE, Corman V, Merle U, Group P, Kurth F, Bernuth H, Meisel C, Goffinet C. Early and rapid identification of COVID-19 patients with neutralizing type I interferon auto-antibodies. J. Clin. Immunol.. 2022 Aug.; 42(6):1111—1129.      [DOI]  [Pubmed] 
Hirschbühl K, Schaller T, Märkl B, Claus R, Sipos E, Rentschler L, Maccagno A, Grosser B, Kling E, Neidig M, Kröncke T, Spring O, Braun G, Bösmüller H, Seidl M, Esposito I, Pablik J, Hilsenbeck J, Boor P, Beer M, Dintner S, Wylezich C. High viral loads: what drives fatal cases of COVID-19 in vaccinees? – an autopsy study. Modern Pathology. 2022 Aug.; 35(8):1013—1021.      [DOI]      [File] 
Fervers P, Kottlors J, Persigehl T, Lennartz S, Maus V, Fischer S, Styczen H, Deuschl C, Schlamann M, Mpotsaris A, Zubel S, Schroeter M, Maintz D, Fink GR, Abdullayev N. Meaningful use of imaging resources to rule out cerebral venous sinus thrombosis after ChAdOx1 COVID-19 vaccination: Evaluation of the AHA diagnostic algorithm with a clinical cohort and a systematic data review.. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 2022 Aug.;      [DOI] 
Jonigk D, Werlein C, Baretton G, Barth P, Bohle RM, Büttner A, Büttner R, Dettmeyer R, Eichhorn P, Elezkurtaj S, Esposito I, Evert K, Evert M, Fend F, Gaßler N, Gattenlöhner S, Glatzel M, Göbel H, Gradhand E, Hansen T, Hartmann A, Heinemann A, Heppner FL, Hilsenbeck J, Horst D, Kamp JC, Mall G, Märkl B, Ondruschka B, Pablik J, Pfefferle S, Quaas A, Radbruch H, Röcken C, Rosenwald A, Roth W, Rudelius M, Schirmacher P, Slotta-Huspenina J, Smith K, Sommer L, Stock K, Ströbel P, Strobl S, Titze U, Weirich G, Weis J, Werner M, Wickenhauser C, Wiech T, Wild P, Welte T, Stillfried S, Boor P. Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies?. Virchows Archiv: An International Journal of Pathology. 2022 Aug.; 481(2):139—159.      [DOI] 
Schons M, Pilgram L, Reese J, Stecher M, Anton G, Appel KS, Bahmer T, Bartschke A, Bellinghausen C, Bernemann I, Brechtel M, Brinkmann F, Brünn C, Dhillon C, Fiessler C, Geisler R, Hamelmann E, Hansch S, Hanses F, Hanß S, Herold S, Heyder R, Hofmann A, Hopff SM, Horn A, Jakob C, Jiru-Hillmann S, Keil T, Khodamoradi Y, Kohls M, Kraus M, Krefting D, Kunze S, Kurth F, Lieb W, Lippert LJ, Lorbeer R, Lorenz-Depiereux B, Maetzler C, Miljukov O, Nauck M, Pape D, Püntmann V, Reinke L, Römmele C, Rudolph S, Sass J, Schäfer C, Schaller J, Schattschneider M, Scheer C, Scherer M, Schmidt S, Schmidt J, Seibel K, Stahl D, Steinbeis F, Störk S, Tauchert M, Tebbe JJ, Thibeault C, Toepfner N, Ungethüm K, Vadasz I, Valentin H, Wiedmann S, Zoller T, Nagel E, Krawczak M, Kalle C, Illig T, Schreiber S, Witzenrath M, Heuschmann P, Vehreschild JJ, Group NR. The German National Pandemic Cohort Network (NAPKON): rationale, study design and baseline characteristics. Eur. J. Epidemiol.. 2022 Aug.; 37(8):849—870.      [DOI]  [Pubmed] 
Stillfried S, Freeborn B, Windeck S, Boor P. Update zur kooperativen autopsiebasierten Forschung in der deutschen Pathologie, Neuropathologie und Gerichtsmedizin. Die Pathologie. 2022 Aug.; 43(Suppl 1):101—105.      [DOI]      [File] 
Scharf G, Meiler S, Zeman F, Schaible J, Poschenrieder F, Knobloch C, Kleine H, Scharf SE, Dinkel J, Stroszczynski C, Zorger N, Hamer OW. Combined Model of Quantitative Evaluation of Chest Computed Tomography and Laboratory Values for Assessing the Prognosis of Coronavirus Disease 2019. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. 2022 Jul.; 194(7):737-746.      [DOI]      [File] 
Aschman T, Mothes R, Heppner FL, Radbruch H. What SARS-CoV-2 does to our brains. Immunity. 2022 Jul.; 55(7):1159—1172.      [DOI] 

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