Publications in the NUM

Tayebi Arasteh S, Kuhl C, Saehn M, Isfort P, Truhn D, Nebelung S. Enhancing domain generalization in the AI-based analysis of chest radiographs with federated learning.. Scientific reports. 2023 Dec.;      [DOI] 

Dadras AA, Jaziri A, Frodl E, Vogl TJ, Dietz J, Bucher AM. Lightweight Techniques to Improve Generalization and Robustness of U-Net Based Networks for Pulmonary Lobe Segmentation.. Bioengineering (Basel, Switzerland). 2023 Dec.;      [DOI] 

Aschman T, Wyler E, Baum O, Hentschel A, Rust R, Legler F, Preusse C, Meyer-Arndt L, Büttnerova I, Förster A, Cengiz D, Alves LGT, Schneider J, Kedor C, Bellmann-Strobl J, Sanchin A, Goebel H, Landthaler M, Corman V, Roos A, Heppner FL, Radbruch H, Paul F, Scheibenbogen C, Dengler NF, Stenzel W. Post-COVID exercise intolerance is associated with capillary alterations and immune dysregulations in skeletal muscles. Acta Neuropathologica Communications. 2023 Dec.; 11(1):193.      [DOI]      [File] 

Lutter M, Kniep I, Ondruschka B, Heinemann A. Pulmonale Befunde in der postmortalen Computertomographie bei COVID-19-assoziierten Todesfällen. Rechtsmedizin. 2023 Dec.; 3417—23.      [DOI]      [File] 

Theis M, Block W, Luetkens JA, Attenberger UI, Nowak S, Sprinkart AM. Direct deep learning-based survival prediction from pre-interventional CT prior to transcatheter aortic valve replacement.. European journal of radiology. 2023 Nov.;      [DOI] 

Nawabi J, Schlunk F, Dell'Orco A, Elsayed S, Mazzacane F, Desser D, Vu L, Vogt E, Cao H, Böhmer MFH, Akkurt BH, Sporns PB, Pasi M, Jensen-Kondering U, Broocks G, Penzkofer T, Fiehler J, Padovani A, Hanning U, Morotti A. Non-contrast computed tomography features predict intraventricular hemorrhage growth.. European radiology. 2023 Nov.;      [DOI] 

Lisson CS, Manoj S, Wolf D, Lisson CG, Schmidt SA, Beer M, Thaiss W, Bolenz C, Zengerling F, Goetz M. Radiomics and Clinicopathological Characteristics for Predicting Lymph Node Metastasis in Testicular Cancer.. Cancers. 2023 Nov.;      [DOI] 

Wolf D, Payer T, Lisson CS, Lisson CG, Beer M, Götz M, Ropinski T. Self-supervised pre-training with contrastive and masked autoencoder methods for dealing with small datasets in deep learning for medical imaging.. Scientific reports. 2023 Nov.;      [DOI] 

Li J, Gsaxner C, Pepe A, Schmalstieg D, Kleesiek J, Egger J. Sparse convolutional neural network for high-resolution skull shape completion and shape super-resolution.. Scientific reports. 2023 Nov.;      [DOI] 

Gierend K, Freiesleben S, Kadioglu D, Siegel F, Ganslandt T, Waltemath D. The Status of Data Management Practices Across German Medical Data Integration Centers: Mixed Methods Study.. Journal of medical Internet research. 2023 Nov.;      [DOI] 

Heinrich F, Mertz KD, Glatzel M, Beer M, Krasemann S. Using autopsies to dissect COVID-19 pathogenesis. Nature Microbiology. 2023 Nov.; 8(11):1986—1994.      [DOI]      [File] 

Appel KS, Geisler R, Maier D, Miljukov O, Hopff SM, Vehreschild JJ. A systematic review of predictor composition, outcomes, risk of bias, and validation of COVID-19 prognostic scores. Clin. Infect. Dis.. 2023 Oct.;      [DOI]  [Pubmed] 

Meyer H, Gottschling S, Borggrefe J, Surov A. CT coronary artery calcification score as a prognostic marker in COVID-19. Journal of thoracic disease. 2023 Oct.; 15(10):5559-5565.      [DOI]      [File] 

Tilch K, Hopff SM, Appel KS, Kraus M, Lorenz-Depiereux B, Pilgram L, Anton G, Berger S, Geisler R, Haas K, Illig T, Krefting D, Lorbeer R, Mitrov L, Muenchhoff M, Nauck M, Pley C, Reese J, Rieg S, Scherer M, Stecher M, Stellbrink C, Valentin H, Winter C, Witzenrath M, Vehreschild JJ. Ethical and coordinative challenges in setting up a national cohort study during the COVID-19 pandemic in Germany. BMC Med. Ethics. 2023 Oct.; 24(1):84.

Engels G, Oechsle A, Schlegtendal A, Maier C, Holzwarth S, Streng A, Lange B, Karch A, Petersmann A, Streeck H, Blaschke-Steinbrecher S, Härtel C, Schroten H, Kries R, Berner R, Liese J, Brinkmann F, Toepfner N. SARS-CoV-2 sero-immunity and quality of life in children and adolescents in relation to infections and vaccinations: the IMMUNEBRIDGE KIDS cross-sectional study, 2022.. Infection. 2023 Oct.;      [DOI] 

Ebel M, Domin M, Neumann N, Schmidt CO, Lotze M, Stanke M. Classifying sex with volume-matched brain MRI.. Neuroimage. Reports. 2023 Sep.;      [DOI] 

Gagiannis D, Hackenbroch C, Bloch W, Zech F, Kirchhoff F, Djudjaj S, Stillfried S, Bülow R, Boor P, Steinestel K. Clinical, Imaging, and Histopathological Features of Pulmonary Sequelae Following Mild COVID-19. American Journal of Respiratory and Critical Care Medicine. 2023 Sep.; 208(5):618-621.      [DOI]      [File] 

Meyer H, Gottschling S, Bär C, Wienke A, Borggrefe J, Surov A. CT coronary calcium score is a prognostic marker in acute pulmonary embolism. Thrombosis research. 2023 Sep.; 229255-257.      [DOI]      [File] 

Stanelle-Bertram S, Beck S, Mounogou NK, Schaumburg B, Stoll F, Schmal Z, Bai T, Zickler M, Beythien G, Becker K, Roi M, Heinrich F, Schulz C, Sauter M, Krasemann S, Lange P, Heinemann A, Riel D, Leijten L, Bauer L, Bosch TPP, Lopuhaä B, Busche T, Wibberg D, Schaudien D, Goldmann T, Lüttjohann A, Ruschinski J, Jania H, Müller Z, Reis V, Krupp-Buzimkic V, Wolff M, Fallerini C, Baldassarri M, Furini S, Norwood K, Käufer C, Schützenmeister N, Köckritz-Blickwede M, Schroeder M, Jarczak D, Nierhaus A, Welte T, Kluge S, McHardy AC, Sommer F, Kalinowski J, Krauss-Etschmann S, Richter F, Thüsen J, Baumgärtner W, Klingel K, Ondruschka B, Renieri A, Gabriel G. CYP19A1 mediates severe SARS-CoV-2 disease outcome in males. Cell Reports Medicine. 2023 Sep.; 4(9):101152.      [DOI]      [File] 

Yusuf KO, Chaplinskaya-Sobol I, Schoneberg A, Hanß S, Valentin H, Lorenz-Depiereux B, Hansch S, Fiedler K, Scherer M, Sikdar S, Miljukov O, Reese J, Wagner P, Bröhl I, Geisler R, Vehreschild JJ, Blaschke S, Bellinghausen C, Milovanovic M, Krefting D. Impact of clinical study implementation on data quality assessments - using contradictions within interdependent health data items as a pilot indicator. Stud. Health Technol. Inform.. 2023 Sep.; 307152—158.      [DOI] 

Baumgärtner GL, Hamm CA, Schulze-Weddige S, Ruppel R, Beetz NL, Rudolph M, Dräger F, Froböse KP, Posch H, Lenk J, Biessmann F, Penzkofer T. Metadata-independent classification of MRI sequences using convolutional neural networks: Successful application to prostate MRI. European journal of radiology. 2023 Sep.; 166110964.      [DOI]      [File] 

Woo MS, Shafiq M, Fitzek A, Dottermusch M, Mohammadi B, Mayer C, Bal LC, Raich L, Matschke J, Krasemann S, Pfefferle S, Brehm TT, Lütgehetmann M, Schädler J, Wiesch J, Ondruschka B, Friese MA, Glatzel M. Vagus nerve inflammation contributes to dysautonomia in COVID-19. Acta Neuropathologica. 2023 Sep.; 146(3):387—394.      [DOI]      [File] 

Salzberger B, Mellmann A, Bludau A, Ciesek S, Corman V, Dilthey A, Donker T, Eckmanns T, Egelkamp R, Gatermann S, Grundmann H, Häcker G, Kaase M, Lange B, Mielke M, Pletz M, Semmler T, Thürmer A, Wieler L, Wolff T, Widmer A, Scheithauer S. An appeal for strengthening genomic pathogen surveillance to improve pandemic preparedness and infection prevention: the German perspective. Infection. 2023 Aug.; 51(4):805—811.      [DOI] 

Jacobs P, Ehrengut C, Bucher AM, Penzkofer T, Lukas M, Kleesiek J, Denecke T. Challenges in Implementing the Local Node Infrastructure for a National Federated Machine Learning Network in Radiology.. Healthcare (Basel, Switzerland). 2023 Aug.;      [DOI] 

Meyer H, Melekh B, Wienke A, Borggrefe J, Surov A. Clinical importance of thoracal lymphadenopathy in COVID-19.. Journal of infection and public health. 2023 Aug.;      [DOI] 

Kolabas ZI, Kuemmerle LB, Perneczky R, Förstera B, Ulukaya S, Kapoor S, Bartos LM, Büttner M, Caliskan OS, Rong Z, Mai H, Höher L, Jeridi D, Molbay M, Khalin I, Deligiannis IK, Negwer M, Roberts K, Simats A, Carofiglio O, Todorov MI, Horvath I, Ozturk F, Hummel S, Biechele G, Zatcepin A, Unterrainer M, Gnörich J, Roodselaar J, Shrouder J, Khosravani P, Tast B, Richter L, Díaz-Marugán L, Kaltenecker D, Lux L, Chen Y, Zhao S, Rauchmann B, Sterr M, Kunze I, Stanic K, Kan VWY, Besson-Girard S, Katzdobler S, Palleis C, Schädler J, Paetzold JC, Liebscher S, Hauser AE, Gokce O, Lickert H, Steinke H, Benakis C, Braun C, Martinez-Jimenez CP, Buerger K, Höglinger G, Levin J, Haass C, Kopczak A, Dichgans M, Havla J, Kümpfel T, Kerschensteiner M, Schifferer M, Simons M, Liesz A, Krahmer N, Bayraktar OA, Franzmeier N, Plesnila N, Erener S, Puelles VG, Delbridge C, Bhatia HS, Hellal F, Elsner M, Bechmann I, Ondruschka B, Brendel M, Theis FJ, Erturk A. Distinct molecular profiles of skull bone marrow in health and neurological disorders. Cell. 2023 Aug.; 186(17):3706-3725.      [DOI]      [File] 

Lange B, Jaeger V, Harries M, R"ucker V, Streeck H, Blaschke S, Petersmann A, Toepfner N, Nauck M, Hassenstein MJ, Dreier M, von Holt I, Budde A, Bartz A, Ortmann J, Kurosinski M, Berner R, Borsche M, Brandhorst G, Brinkmann M, Budde K, Deckena M, Engels G, Fenzlaff M, Härtel C, Hovardovska O, Katalinic A, Kehl K, Kohls M, Krüger S, Lieb W, Meyer-Schlinkmann KM, Pischon T, Rosenkranz D, Rübsamen N, Rupp J, Schäfer C, Schattschneider M, Schlegtendal A, Schlinkert S, Schmidbauer L, Schulze-Wundling K, Störk S, Tiemann C, V"olzke H, Winter T, Klein C, Liese J, Brinkmann F, Ottensmeyer PF, Reese J, Heuschmann P, Karch A. Estimates of protection levels against SARS-CoV-2 infection and severe COVID-19 in Germany before the 2022/2023 winter season: the IMMUNEBRIDGE project. Infection. 2023 Aug.;      [DOI] 

Granai M, Warm V, Vogelsberg A, Milla J, Greif K, Vogel U, Bakchoul T, Rosenberger P, Quintanilla-Martinez L, Schürch C, Klingel K, Fend F, Bösmüller H. Impact of P-selectin-PSGL-1 Axis on Platelet-Endothelium-Leucocyte Interactions in Fatal COVID-19. Laboratory Investigation; a Journal of Technical Methods and Pathology. 2023 Aug.; 103(8):100179.      [DOI]      [File] 

Lücke J, Heinrich F, Malsy J, Meins N, Schnell J, Böttcher M, Nawrocki M, Zhang T, Bertram F, Sabihi M, Kempski J, Blankenburg T, Duprée A, Reeh M, Wolter S, Mann O, Izbicki JR, Lohse AW, Gagliani N, Lütgehetmann M, Bunders MJ, Altfeld M, Sauter G, Giannou AD, Krasemann S, Ondruschka B, Huber S. Intestinal IL-1β Plays a Role in Protecting against SARS-CoV-2 Infection. The Journal of Immunology. 2023 Aug.; 211(6):1052–1061.      [DOI]      [File] 

Azeke AT, Schädler J, Ondruschka B, Steurer S, Möbius D, Fitzek A. Minimally Invasive Tissue Sampling via Post Mortem Ultrasound: A Feasible Tool (Not Only) in Infectious Diseases-A Case Report. Diagnostics (Basel, Switzerland). 2023 Aug.; 13(16):2643.      [DOI]      [File] 

Surov A, Thormann M, Bär C, Wienke A, Borggrefe J. Validation of clinical-radiological scores for prognosis of mortality in acute pulmonary embolism.. Respiratory research. 2023 Aug.;      [DOI] 

Haag F, Pech M, Surov A. [Chronic-intermittent diffuse alveolar hemorrhage of unknown origin]. RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. 2023 Jul.; 195(7):620-622.      [DOI]      [File] 

Steinbeis F, Thibeault C, Steinbrecher S, Haack IA, August D, Balzuweit B, Bellinghausen C, Berger S, Chaplinskaya-Sobol I, Cornely O, Doeblin P, Endres M, Fink C, Finke C, Frank S, Hanß S, Hartung T, Hellmuth JC, Herold S, Heuschmann P, Heyckendorf J, Heyder R, Hippenstiel S, Hoffmann W, Kelle SU, Knape P, Koehler P, Kretzler L, Leistner DM, Lienau J, Lorbeer R, Lorenz-Depiereux B, Lüttke CD, Mai K, Merle U, Meyer-Arndt LA, Miljukov O, Muenchhoff M, Müller-Plathe M, Neuhann J, Neuhauser H, Nieters A, Otte C, Pape D, Pinto R, Pley C, Pudszuhn A, Reuken P, Rieg S, Ritter P, Rohde G, Rönnefarth M, Ruzicka M, Schaller J, Schmidt A, Schmidt S, Schwachmeyer V, Schwanitz G, Seeger W, Stahl D, Stobäus N, Stubbe HC, Suttorp N, Temmesfeld B, Thun S, Triller P, Trinkmann F, Vadasz I, Valentin H, Vehreschild M, Kalle C, Lilienfeld-Toal M, Weber J, Welte T, Wildberg C, Wizimirski R, Zvork S, Sander LE, Vehreschild J, Zoller T, Kurth F, Witzenrath M. Analysis of acute COVID-19 including chronic morbidity: protocol for the deep phenotyping National Pandemic Cohort Network in Germany (NAPKON-HAP). Infection. 2023 Jul.; 52(1):93-104.      [DOI]  [Pubmed] 

Pappe E, Hammerich R, Saccomanno J, Sgarbossa T, Pohrt A, Schmidt B, Grah C, Eisenmann S, Holland A, Eggeling S, Stanzel F, Witzenrath M, Hübner R. Impact of Coronavirus disease 2019 on hospital admissions, health status, and behavioral changes of patients with COPD. Chronic Obstr. Pulm. Dis.. 2023 Jul.; 10(3):211—223.      [DOI] 

Kolck J, Rako ZA, Beetz NL, Auer TA, Segger LK, Pille C, Penzkofer T, Fehrenbach U, Geisel D. Intermittent body composition analysis as monitoring tool for muscle wasting in critically ill COVID-19 patients.. Annals of intensive care. 2023 Jul.;      [DOI] 

Lichtner G, Haese T, Brose S, Röhrig L, Lysyakova L, Rudolph S, Uebe M, Sass J, Bartschke A, Hillus D, Kurth F, Sander LE, Eckart F, Toepfner N, Berner R, Frey A, Dörr M, Vehreschild JJ, Kalle C, Thun S. Interoperable, domain-specific extensions for the German Corona Consensus (GECCO) COVID-19 research data set using an interdisciplinary, consensus-based workflow: Data set development study. JMIR Med. Inform.. 2023 Jul.; 11e45496.      [DOI]  [Pubmed] 

Khader F, Kather JN, Müller-Franzes G, Wang T, Han T, Tayebi Arasteh S, Hamesch K, Bressem K, Haarburger C, Stegmaier J, Kuhl C, Nebelung S, Truhn D. Medical transformer for multimodal survival prediction in intensive care: integration of imaging and non-imaging data.. Scientific reports. 2023 Jul.;      [DOI] 

Schweizer L, Schaller T, Zwiebel M, Karayel Ö, Müller‐Reif JB, Zeng W, Dintner S, Nordmann TM, Hirschbühl K, Märkl B, Claus R, Mann M. Quantitative multiorgan proteomics of fatal COVID‐19 uncovers tissue‐specific effects beyond inflammation. EMBO Molecular Medicine. 2023 Jul.; 15(9):e17459.      [DOI]      [File] 

Rogasch JMM, Michaels L, Baumgärtner GL, Frost N, Rückert J, Neudecker J, Ochsenreither S, Gerhold M, Schmidt B, Schneider P, Amthauer H, Furth C, Penzkofer T. A machine learning tool to improve prediction of mediastinal lymph node metastases in non-small cell lung cancer using routinely obtainable [18F]FDG-PET/CT parameters. European journal of nuclear medicine and molecular imaging. 2023 Jun.; 50(7):2140-2151.      [DOI]      [File] 

Krämer M, Ingwersen M, Teichgräber U, Güttler F. Added value of chest CT in a machine learning-based prediction model to rule out COVID-19 before inpatient admission: A retrospective university network study. European journal of radiology. 2023 Jun.; 163110827.      [DOI]      [File] 

Meng F, Kottlors J, Shahzad R, Liu H, Fervers P, Jin Y, Rinneburger M, Le D, Weisthoff M, Liu W, Ni M, Sun Y, An L, Huai X, Móré D, Giannakis A, Kaltenborn I, Bucher A, Maintz D, Zhang L, Thiele F, Li M, Perkuhn M, Zhang H, Persigehl T. AI support for accurate and fast radiological diagnosis of COVID-19: an international multicenter, multivendor CT study.. European radiology. 2023 Jun.;      [DOI] 

Meiler S, Poschenrieder F, Mohr A, Strotzer Q, Scharf G, Rennert J, Stroszczynski C, Pfeifer M, Hamer O. CT findings in "Post-Covid": residua from acute pneumonia or "Post-Covid-ILD"?. Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG. 2023 Jun.; 40(2):e2023024.      [DOI]      [File] 

Meyer H, Kardas H, Schramm D, Bär C, Wienke A, Borggrefe J, Surov A. CT-defined pectoralis muscle mass and muscle density are associated with mortality in acute pulmonary embolism. A multicenter analysis. Clinical nutrition (Edinburgh, Scotland). 2023 Jun.; 42(6):1036-1040.      [DOI]      [File] 

Cao H, Morotti A, Mazzacane F, Desser D, Schlunk F, Güttler C, Kniep H, Penzkofer T, Fiehler J, Hanning U, Dell'Orco A, Nawabi J. External Validation and Retraining of DeepBleed: The First Open-Source 3D Deep Learning Network for the Segmentation of Spontaneous Intracerebral and Intraventricular Hemorrhage.. Journal of clinical medicine. 2023 Jun.;      [DOI] 

Gertz RJ, Bunck AC, Lennartz S, Dratsch T, Iuga A, Maintz D, Kottlors J. GPT-4 for Automated Determination of Radiological Study and Protocol based on Radiology Request Forms: A Feasibility Study. Radiology. 2023 Jun.; 307(5):e230877.      [DOI]      [File] 

Liu Z, Hollmann C, Kalanidhi S, Grothey A, Keating S, Mena-Palomo I, Lamer S, Schlosser A, Kaiping A, Scheller C, Sotzny F, Horn A, Nürnberger C, Cejka V, Bahmer T, Schreiber S, Vehreschild JJ, Miljukov O, Schäfer C, Kretzler L, Keil T, Reese J, Eichner FA, Schmidbauer L, Heuschmann PU, Störk S, Morbach C, Riemekasten G, Beyersdorf N, Scheibenbogen C, Naviaux RK, Williams M, Ariza ME, Prusty BK. Increased circulating fibronectin, depletion of natural IgM and heightened EBV, HSV-1 reactivation in ME/CFS and long COVID. medRxiv. 2023 Jun.; Online ahead of print      [DOI]  [Pubmed] 

Ebong U, Büttner SM, Schmidt SA, Flack F, Korf P, Peters L, Grüner B, Stenger S, Stamminger T, Kestler H, Beer M, Kloth C. Quantitative Evaluation of COVID-19 Pneumonia CT Using AI Analysis-Feasibility and Differentiation from Other Common Pneumonia Forms.. Diagnostics (Basel, Switzerland). 2023 Jun.;      [DOI] 

Bräutigam K, Reinhard S, Wartenberg M, Forster S, Greif K, Granai M, Bösmüller H, Klingel K, Schürch CM. Comprehensive analysis of SARS-CoV-2 receptor proteins in human respiratory tissues identifies alveolar macrophages as potential virus entry site. Histopathology. 2023 May; 82(6):846—859.      [DOI] 

Leonhardi J, Bailis N, Lerche M, Denecke T, Surov A, Meyer H. Computed Tomography Embolus Texture Analysis as a Prognostic Marker of Acute Pulmonary Embolism. Angiology. 2023 May; 74(5):461-471.      [DOI]      [File] 

Schulze-Wundling K, Ottensmeyer PF, Meyer-Schlinkmann KM, Deckena M, Krüger S, Schlinkert S, Budde A, Münstermann D, Töpfner N, Petersmann A, Nauck M, Karch A, Lange B, Blaschke S, Tiemann C, Streeck H. Immunity against SARS-CoV-2 in the German population. Dtsch. Arztebl. Int.. 2023 May; 120(19):337—344.      [DOI]